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OverviewAI-generated summary
Li Han's research focuses on cancer treatment and molecular mechanisms, with publications addressing immunotherapy, targeted therapies, and prognostic markers. This includes work on sintilimab combined with chemotherapy for advanced gastric or gastroesophageal junction adenocarcinoma, and transarterial chemoembolization combined with lenvatinib and PD-1 inhibitors for hepatocellular carcinoma. Han has also investigated predictive models for treatment response in hepatocellular carcinoma, such as the TAE score.
Further research delves into the molecular underpinnings of disease. This includes exploring how circRNA DOCK1 regulates specific gene axes to modulate cell proliferation and apoptosis in vascular smooth muscle cells. Han has also contributed to understanding the role of pyroptosis-related signatures in predicting prognosis and treatment response in breast carcinoma. Additionally, studies have examined the effects of compounds like resveratrol in alleviating pulmonary fibrosis by suppressing key molecular pathways.
Metrics
- h-index: 26
- Publications: 153
- Citations: 2,611
Selected Publications
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Tumor Intrinsic METTL5 Modulates ATF4 Translation to Prevent T Cell‐Induced Ferroptosis in Ovarian Cancer (2025)
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Organic Polymer Semiconductor Photocatalysts: From Building Block Design to Controllable Assembly (2025)
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Cisplatin-induced WWP1-eccDNA expression contributes to ovarian cancer resistance (2025)
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Dual roles and therapeutic potential of ALDH3 family members in cancer (2025)
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Dual-stage modulation correlation OTDR for high-resolution monitoring in passive optical networks (2025)
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Prognostic Value of Clinical Complete Response for Patients with Initially Unresectable Hepatocellular Carcinoma after Conversion with Triple Therapy (2025)
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NR4A1 silencing alleviates high-glucose-stimulated HK-2 cells pyroptosis and fibrosis <i>via</i> hindering NLRP3 activation and PI3K/AKT pathway (2025)
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End-to-End Information Extraction from Courier Order Images Using a Neural Network Model with Feature Enhancement (2025)
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A tetrahedral DNA nanoplatform with ultrasound-triggered biomimetic nanocarriers for targeted siMCM2 delivery and reversal of imatinib resistance in gastrointestinal stromal tumors (2024)
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Advancing Transcranial Focused Ultrasound for Neuromodulation: Integration of Pseudo-brain Model into Simulations (2024)
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Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment (2024)
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The efficacy and safety of proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors combined with statins in patients with hypercholesterolemia: a network meta-analysis (2024)
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Impact of Duration of Adjuvant Therapy on Patients with Initially Unresectable Hepatocellular Carcinoma After Conversion Surgery: A Propensity Score Matching Study (2024)
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Myosteatosis and the clinical outcomes of patients with liver cirrhosis: A meta-analysis (2024)
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Vaccinia virus Tiantan strain blocks host antiviral innate immunity and programmed cell death by disrupting gene expression (2024)
Collaboration Network
Top Collaborators
Kelei Guo
Nanyang Institute of Technology (CN)
8 shared publications
- Two decades of a protooncogene TBL1XR1: from a transcription modulator to cancer therapeutic target
- Th17 cell‐derived <i>miR‐155‐5p</i> modulates interleukin‐17 and suppressor of cytokines signaling 1 expression during the progression of systemic sclerosis
- FSTL1: A double-edged sword in cancer development
- Identification of key genes and pathways related to cancer-associated fibroblasts in chemoresistance of ovarian cancer cells based on GEO and TCGA databases
- Wenyang Huazhuo Tongluo formula alleviates pulmonary vascular injury and downregulates HIF-1α in bleomycin-induced systemic sclerosis mouse model
Showing 5 of 8 shared publications
Hua Bian
Nanyang Institute of Technology (CN)
8 shared publications
- Two decades of a protooncogene TBL1XR1: from a transcription modulator to cancer therapeutic target
- Th17 cell‐derived <i>miR‐155‐5p</i> modulates interleukin‐17 and suppressor of cytokines signaling 1 expression during the progression of systemic sclerosis
- FSTL1: A double-edged sword in cancer development
- Identification of key genes and pathways related to cancer-associated fibroblasts in chemoresistance of ovarian cancer cells based on GEO and TCGA databases
- Wenyang Huazhuo Tongluo formula alleviates pulmonary vascular injury and downregulates HIF-1α in bleomycin-induced systemic sclerosis mouse model
Showing 5 of 8 shared publications
Zefeng Liu
Tianjin Medical University General Hospital (CN)
8 shared publications
- Detection of the gene mutation of epidermal growth factor receptor in lung adenocarcinoma by radiomic features from a small amount of PET data
- Correction: Applications of radiomics‑based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 17 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 5 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 10 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
Showing 5 of 8 shared publications
Tianyou Zhang
Tianjin Medical University General Hospital (CN)
8 shared publications
- Detection of the gene mutation of epidermal growth factor receptor in lung adenocarcinoma by radiomic features from a small amount of PET data
- Correction: Applications of radiomics‑based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 17 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 5 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 10 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
Showing 5 of 8 shared publications
Fenghua Long
Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
8 shared publications
- Detection of the gene mutation of epidermal growth factor receptor in lung adenocarcinoma by radiomic features from a small amount of PET data
- Correction: Applications of radiomics‑based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 17 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 5 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 10 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
Showing 5 of 8 shared publications
Liying Lin
Tianjin Medical University (CN)
7 shared publications
- Correction: Applications of radiomics‑based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 17 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 5 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 10 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 19 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
Showing 5 of 7 shared publications
Hongyu Guo
Tianjin Medical University General Hospital (CN)
7 shared publications
- Correction: Applications of radiomics‑based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 17 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 5 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 10 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
- Additional file 19 of Applications of radiomics-based analysis pipeline for predicting epidermal growth factor receptor mutation status
Showing 5 of 7 shared publications
Ruijuan Du
Nanyang Institute of Technology (CN)
6 shared publications
- Two decades of a protooncogene TBL1XR1: from a transcription modulator to cancer therapeutic target
- FSTL1: A double-edged sword in cancer development
- Identification of key genes and pathways related to cancer-associated fibroblasts in chemoresistance of ovarian cancer cells based on GEO and TCGA databases
- Prediction and verification of the key ingredients and molecular targets of Guizhi Fuling capsule against tumour metastasis and resistance
- Chaperonin-containing TCP-1 subunit genes are potential prognostic biomarkers and are correlated with Th2 cell infiltration in lung adenocarcinoma: An observational study
Showing 5 of 6 shared publications
Jiayi Wu
Fujian Provincial Hospital (CN)
5 shared publications
- Transarterial Chemoembolization Plus Lenvatinib and PD-1 Inhibitors for Hepatocellular Carcinoma with Main Trunk Portal Vein Tumor Thrombus: A Multicenter Retrospective Study
- Transarterial Chemoembolization Plus Lenvatinib and PD-1 Inhibitors for Hepatocellular Carcinoma with Main Trunk Portal Vein Tumor Thrombus: A Multicenter Retrospective Study
- The TAE score predicts prognosis of unresectable HCC patients treated with TACE plus lenvatinib with PD-1 inhibitors
- Prediction of early treatment response to the combination therapy of TACE plus lenvatinib and anti-PD-1 antibody immunotherapy for unresectable hepatocellular carcinoma: Multicenter retrospective study
- Prognostic Value of Clinical Complete Response for Patients with Initially Unresectable Hepatocellular Carcinoma after Conversion with Triple Therapy
Mao-Lin Yan
Fujian Medical University (CN)
4 shared publications
- Transarterial Chemoembolization Plus Lenvatinib and PD-1 Inhibitors for Hepatocellular Carcinoma with Main Trunk Portal Vein Tumor Thrombus: A Multicenter Retrospective Study
- The TAE score predicts prognosis of unresectable HCC patients treated with TACE plus lenvatinib with PD-1 inhibitors
- Prediction of early treatment response to the combination therapy of TACE plus lenvatinib and anti-PD-1 antibody immunotherapy for unresectable hepatocellular carcinoma: Multicenter retrospective study
- Prognostic Value of Clinical Complete Response for Patients with Initially Unresectable Hepatocellular Carcinoma after Conversion with Triple Therapy
Qin Lv
Nanyang Medical College (CN)
3 shared publications
- Th17 cell‐derived <i>miR‐155‐5p</i> modulates interleukin‐17 and suppressor of cytokines signaling 1 expression during the progression of systemic sclerosis
- Wenyang Huazhuo Tongluo formula alleviates pulmonary vascular injury and downregulates HIF-1α in bleomycin-induced systemic sclerosis mouse model
- Prediction and verification of the key ingredients and molecular targets of Guizhi Fuling capsule against tumour metastasis and resistance
Kai Li
Nanyang Institute of Technology (CN)
3 shared publications
- Two decades of a protooncogene TBL1XR1: from a transcription modulator to cancer therapeutic target
- FSTL1: A double-edged sword in cancer development
- Wenyang Huazhuo Tongluo formula alleviates pulmonary vascular injury and downregulates HIF-1α in bleomycin-induced systemic sclerosis mouse model
Junyi Wu
Fuzhou University (CN)
3 shared publications
- The TAE score predicts prognosis of unresectable HCC patients treated with TACE plus lenvatinib with PD-1 inhibitors
- Prediction of early treatment response to the combination therapy of TACE plus lenvatinib and anti-PD-1 antibody immunotherapy for unresectable hepatocellular carcinoma: Multicenter retrospective study
- Prognostic Value of Clinical Complete Response for Patients with Initially Unresectable Hepatocellular Carcinoma after Conversion with Triple Therapy
Yinan Li
Fujian Medical University (CN)
3 shared publications
- The TAE score predicts prognosis of unresectable HCC patients treated with TACE plus lenvatinib with PD-1 inhibitors
- Prediction of early treatment response to the combination therapy of TACE plus lenvatinib and anti-PD-1 antibody immunotherapy for unresectable hepatocellular carcinoma: Multicenter retrospective study
- Prognostic Value of Clinical Complete Response for Patients with Initially Unresectable Hepatocellular Carcinoma after Conversion with Triple Therapy
Zhen-Xin Zeng
Fujian Medical University (CN)
3 shared publications
- Transarterial Chemoembolization Plus Lenvatinib and PD-1 Inhibitors for Hepatocellular Carcinoma with Main Trunk Portal Vein Tumor Thrombus: A Multicenter Retrospective Study
- The TAE score predicts prognosis of unresectable HCC patients treated with TACE plus lenvatinib with PD-1 inhibitors
- Prognostic Value of Clinical Complete Response for Patients with Initially Unresectable Hepatocellular Carcinoma after Conversion with Triple Therapy
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