Lyle Burdine
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Also affiliated: University of Arkansas Medical Center (2026); Arkansas Children's Research Institute (2026)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Lyle Burdine's research has focused on several areas, including the molecular mechanisms of cancer treatment and surgical outcomes. He has investigated the chemical genetics of drug targets and the chemistry of cross-linking molecules, particularly those containing DOPA, to proteins. His work has also extended to clinical studies, including a large retrospective analysis of surgical outcomes for gallbladder cancer and a machine learning-based risk prediction score for mortality in patients undergoing surgery with perioperative SARS-CoV-2 infection. Burdine has also contributed to systematic reviews and meta-analyses, such as one examining adjuvant transarterial chemoembolization following hepatectomy for hepatocellular carcinoma. His scholarship metrics include an h-index of 18, 79 total publications, and 1,036 total citations. He has collaborated with researchers at the University of Arkansas for Medical Sciences, including Steven R. Post, Yong-Chen Lu, and Catherine Kirkpatrick.
Metrics
- h-index: 1
- Publications: 4
- Citations: 3
Selected Publications
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Geographic Distance to the Liver Transplant Center is Not Associated with Inferior Liver Transplant Outcomes with Careful Distance Follow-Up Strategy (2026)
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A Fatal Case of Renal Mucormycosis Complicated by Renal Vein Thrombosis in Kidney Transplant (2026)
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Acellular normothermic spleen perfusion resolves transcriptional and non-transcriptional mechanisms of steroid immunosuppression (2026)
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L15. T Cell-Specific Loss of DNA-PKcs Enhances Allogeneic Cardiac Graft Survival (2026)
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Menopausal status modifies waitlist outcomes in women with metabolic-associated steatotic liver disease under MELD 3.0 allocation (2026)
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Drug-coated balloon angioplasty with a focus on solid organ transplantation: a promising paradigm shift in cardiovascular interventions (2026)
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DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling (2026)
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A functional surface display system in Saccharomyces boulardii for protein absorption in simulated intestinal fluids (2025)
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Inferior Waitlist Outcomes Among Patients Listed for Simultaneous Liver-Kidney Transplantation (2025)
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Potential Different Reactivities of Intra-Graft and Serum Donor-Specific Antibodies in Liver and Kidney Transplantation (2025)
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Military Share Deceased Donor Initiated Chains (2025)
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Examining Differential Transplantation Rates and Outcomes by Center Volume During Weekend and Holidays (2025)
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DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling (2025)
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DNA-PKcs governs LAT-dependent signaling in CD4 + and CD8 + T cells (2025)
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Kidney Utilization in the Context of a Shifting Donor Landscape in the United States (2024)
Collaboration Network
Top Collaborators
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
- DNA-PKcs Inhibition Extends Allogeneic Skin Graft Survival
- DNA-PKcs controls calcineurin mediated IL-2 production in T lymphocytes
- Impact of Prolonged Cold Ischemia Time on One Year Kidney Transplant Outcomes
- Proteomic Identification of DNA-PK Involvement within the RET Signaling Pathway
Showing 5 of 22 shared publications
- Adjuvant Transarterial Chemoembolization Following Curative-Intent Hepatectomy Versus Hepatectomy Alone for Hepatocellular Carcinoma: A Systematic Review and Meta-Analysis of Randomized Controlled Trials
- Comparable graft survival is achievable with the usage of donation after circulatory death liver grafts from donors at or above 70 years of age: A long-term UK national analysis
- COVID-19 Mortality in Vaccinated vs. Unvaccinated Liver & Kidney Transplant Recipients: A Single-Center United States Propensity Score Matching Study on Historical Data
- Disparities in the Use of Older Donation After Circulatory Death Liver Allografts in the United States Versus the United Kingdom
- Acuity circles allocation policy impact on waitlist mortality and donation after circulatory death liver transplantation: A nationwide retrospective analysis
Showing 5 of 18 shared publications
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
- DNA-PKcs Inhibition Extends Allogeneic Skin Graft Survival
- Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells
- Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
Showing 5 of 15 shared publications
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
- Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells
- Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
- DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling
Showing 5 of 12 shared publications
- COVID-19 Mortality in Vaccinated vs. Unvaccinated Liver & Kidney Transplant Recipients: A Single-Center United States Propensity Score Matching Study on Historical Data
- COVID‐19 in solid organ transplant recipients
- Impact of Prolonged Cold Ischemia Time on One Year Kidney Transplant Outcomes
- Kidney Utilization in the Context of a Shifting Donor Landscape in the United States
- SARS-CoV-2 Infection of Unvaccinated Liver- and Kidney-Transplant Recipients: A Single-Center Experience of 103 Consecutive Cases
Showing 5 of 9 shared publications
- COVID-19 Mortality in Vaccinated vs. Unvaccinated Liver & Kidney Transplant Recipients: A Single-Center United States Propensity Score Matching Study on Historical Data
- Acuity circles allocation policy impact on waitlist mortality and donation after circulatory death liver transplantation: A nationwide retrospective analysis
- Kidney Utilization in the Context of a Shifting Donor Landscape in the United States
- SARS-CoV-2 Infection of Unvaccinated Liver- and Kidney-Transplant Recipients: A Single-Center Experience of 103 Consecutive Cases
- Negative COVID-19 Plasma PCR Following COVID-19+ Donor Kidney Transplant
Showing 5 of 9 shared publications
- COVID-19 Mortality in Vaccinated vs. Unvaccinated Liver & Kidney Transplant Recipients: A Single-Center United States Propensity Score Matching Study on Historical Data
- Acuity circles allocation policy impact on waitlist mortality and donation after circulatory death liver transplantation: A nationwide retrospective analysis
- Impact of Prolonged Cold Ischemia Time on One Year Kidney Transplant Outcomes
- Kidney Utilization in the Context of a Shifting Donor Landscape in the United States
- SARS-CoV-2 Infection of Unvaccinated Liver- and Kidney-Transplant Recipients: A Single-Center Experience of 103 Consecutive Cases
Showing 5 of 9 shared publications
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
- DNA-PKcs Inhibition Extends Allogeneic Skin Graft Survival
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
- 10399 DNA-PK(cs) Regulates Stability of Egr1 During T Cell Activation
- DNA-PKcs Inhibition Extends Allogeneic Skin Graft Survival and Suppresses EGR1 and NFκB-mediated IL6 Production
Showing 5 of 6 shared publications
- COVID-19 Mortality in Vaccinated vs. Unvaccinated Liver & Kidney Transplant Recipients: A Single-Center United States Propensity Score Matching Study on Historical Data
- Women Referred for Liver Transplant Are Less Likely to Be Transplanted Irrespective of Socioeconomic Status
- SARS-CoV-2 Infection of Unvaccinated Liver- and Kidney-Transplant Recipients: A Single-Center Experience of 103 Consecutive Cases
- Drug-coated balloon angioplasty with a focus on solid organ transplantation: a promising paradigm shift in cardiovascular interventions
- 230.4: COVID-19 Mortality in Vaccinated vs. Unvaccinated Solid Organ Transplant Recipients: A Single Center United States Propensity Score Matching Study
Showing 5 of 6 shared publications
- Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells
- Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441
- A functional surface display system in Saccharomyces boulardii for protein absorption in simulated intestinal fluids
- DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling
- DNA-PKcs governs LAT-dependent signaling in CD4 + and CD8 + T cells
Showing 5 of 6 shared publications
- Comparable graft survival is achievable with the usage of donation after circulatory death liver grafts from donors at or above 70 years of age: A long-term UK national analysis
- Disparities in the Use of Older Donation After Circulatory Death Liver Allografts in the United States Versus the United Kingdom
- Acuity circles allocation policy impact on waitlist mortality and donation after circulatory death liver transplantation: A nationwide retrospective analysis
- Centre volume impact on graft survival and waiting list time in donation after circulatory death liver transplantation in the USA
- Cover Image, Volume 6, Issue 2
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
- DNA-PKcs kinase activity stabilizes the transcription factor Egr1 in activated immune cells
- DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling
- DNA-PKcs governs LAT-dependent signaling in CD4 + and CD8 + T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
- Chemical inhibition of DNA‐PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells
- DNA-PKcs controls the cytotoxic T cell response to cancer and transplant allograft through regulating LAT-dependent signaling
- Inhibition of DNA-PKcs impairs the activation and cytotoxicity of CD4 + helper and CD8 + effector T cells
- DNA-PKcs governs LAT-dependent signaling in CD4 + and CD8 + T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
- Percutaneous Cholecystostomy Tubes versus Medical Management for Acute Cholecystitis
- Impact of Prolonged Cold Ischemia Time on One Year Kidney Transplant Outcomes
- National Readmissions Database characterization of post-cholecystectomy care for inpatients: Readmissions and bile duct repair
- Incidence of Red Cell Antibody Formation Following Massive Transfusion Protocol: Experience of a Single Institution
- COVID-19 Mortality in Vaccinated vs. Unvaccinated Liver & Kidney Transplant Recipients: A Single-Center United States Propensity Score Matching Study on Historical Data
- SARS-CoV-2 Infection of Unvaccinated Liver- and Kidney-Transplant Recipients: A Single-Center Experience of 103 Consecutive Cases
- 230.4: COVID-19 Mortality in Vaccinated vs. Unvaccinated Solid Organ Transplant Recipients: A Single Center United States Propensity Score Matching Study
- 210.7: Undetectable Recipient COVID-19 Plasma PCR Following COVID-19 Positive Donor Kidney Transplant: Proof of Concept Analysis
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