Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
R
Randall R Rainwater
MD/PhD student
Also affiliated: Arkansas Children's Hospital (2023–2025); Johns Hopkins University (2025); Arkansas Children's Nutrition Center (2025)
Graduate Student Researcher
3 h-index
15 pubs
19 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Randall R Rainwater's research has focused on the molecular mechanisms of cell death pathways and the development of targeted therapeutic agents. His work includes investigating the role of DNA-activated protein kinase catalytic subunit (DNA-PKcs) in T cell activation and cytotoxicity, identifying inhibitors like DA-143 that demonstrate improved solubility. Rainwater has also explored the susceptibility of primary acute lymphoblastic leukemia cells to microtubule depolymerization and distinct cell death pathways in different cell cycle phases. Additionally, his research has examined gastrointestinal mucosal cell injury associated with sevelamer crystals, contributing to medical case reports and literature reviews. His scholarly contributions are reflected in 14 publications and an h-index of 3, with recent activity indicating ongoing research endeavors.
Metrics
- h-index: 3
- Publications: 15
- Citations: 19
Selected Publications
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Response to Letter to the Editor “Gastrointestinal Mucosal Cell Injury Caused by Sevelamer " (2026)
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Seasonal, Regional, and Clinical Factors Associated With Manipulation Under Anesthesia Following Total Knee Arthroplasty: A PearlDiver Study (2026)
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Thoracic outlet syndrome in patients with clavicle fracture: Case report and national analysis (2026)
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Acellular normothermic spleen perfusion resolves transcriptional and non-transcriptional mechanisms of steroid immunosuppression (2026)
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Pregnancy with peritoneal dialysis- a challenge revisited (2026)
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Promising Clinical Outcomes Using Rotational Achilles Autograft for Knee Arthroplasty Terrible Triad (2026)
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L15. T Cell-Specific Loss of DNA-PKcs Enhances Allogeneic Cardiac Graft Survival (2026)
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Outpatient Management of Slipped Capital Femoral Epiphysis Is Common, Safe, and Saves Costs: A Single-Institution Analysis and Results From a National Database Survey (2026)
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Thoracic outlet syndrome in patients with Clavicle Fracture: Case report and national analysis (2026)
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Postoperative complications following total shoulder arthroplasty in multiple myeloma patients with prior bone marrow transplantation (2026)
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A step-by-step protocol for isolation and flow cytometry analysis of porcine cardiac valve leaflets (2025)
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The Impact of Bone Marrow Transplant on Total Joint Arthroplasty Outcomes in Patients Diagnosed With Multiple Myeloma (2025)
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A functional surface display system in Saccharomyces boulardii for protein absorption in simulated intestinal fluids (2025)
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DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling (2025)
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DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells (2025)
Collaboration Network
Top Collaborators
Lyle Burdine
University of Arkansas for Medical Sciences
5 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441
- DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
- A functional surface display system in Saccharomyces boulardii for protein absorption in simulated intestinal fluids
Zachary J. Waldrip
Arkansas Children's Hospital
5 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441
- DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
- A functional surface display system in Saccharomyces boulardii for protein absorption in simulated intestinal fluids
Marie Burdine
Arkansas Children's Hospital (US)
5 shared publications
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441
- DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
- A functional surface display system in Saccharomyces boulardii for protein absorption in simulated intestinal fluids
Ana Clara P. Azevedo‐Pouly
University of Arkansas for Medical Sciences
4 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- Discovery of the DNA-PKcs inhibitor DA-143 which exhibits enhanced solubility relative to NU7441
- DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
Brian Koss
University of Arkansas for Medical Sciences
3 shared publications
In database
- Chemical inhibition of <scp>DNA‐PKcs</scp> impairs the activation and cytotoxicity of <scp>CD4</scp><sup>+</sup> helper and <scp>CD8</scp><sup>+</sup> effector T cells
- DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
B.R. Hicks
University of Arkansas for Medical Sciences
2 shared publications
In database
- DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
Nicholas A. Callais
University of Arkansas for Medical Sciences (US)
2 shared publications
- DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
Aaron J. Storey
Arkana Laboratories
2 shared publications
In database
- DNA-PKcs governs LAT-dependent signaling in CD4 <sup>+</sup> and CD8 <sup>+</sup> T cells
- DNA-PKcs Controls the Cytotoxic T-Cell Response to Cancer and Transplant Allograft Through Regulating LAT-Dependent Signaling
Simon C. Mears
University of Arkansas for Medical Sciences
2 shared publications
In database
- The Impact of Bone Marrow Transplant on Total Joint Arthroplasty Outcomes in Patients Diagnosed With Multiple Myeloma
- Postoperative complications following total shoulder arthroplasty in multiple myeloma patients with prior bone marrow transplantation
Benjamin M. Stronach
University of Arkansas Medical Center
2 shared publications
In database
- The Impact of Bone Marrow Transplant on Total Joint Arthroplasty Outcomes in Patients Diagnosed With Multiple Myeloma
- Promising Clinical Outcomes Using Rotational Achilles Autograft for Knee Arthroplasty Terrible Triad
Arijit Mukherjee
University of Central Arkansas (US)
1 shared publication
- The legume-rhizobia symbiosis can be supported on Mars soil simulants
Magdalena Delgado
University of Arkansas for Medical Sciences (US)
1 shared publication
- Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways
Billie Heflin
University of Arkansas for Medical Sciences
1 shared publication
In database
- Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways
Alicja Urbaniak
University of Arkansas for Medical Sciences
1 shared publication
In database
- Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways
Kaitlynn Butler
University of Arkansas for Medical Sciences
1 shared publication
In database
- Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways
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