Oleksandra Pavliv

High Impact

Research Assistant

UAMS

Also affiliated: Arkansas Children's Hospital (2008–2017); University of Arkansas Medical Center (2023); Arkansas Children's Nutrition Center (2025); Arkansas Children's Research Institute (2008–2025)

20 h-index 31 pubs 2,526 cited

Research Areas

Biomedical Subjects

Links

ORCID Research Group

OverviewAI-generated summary

Oleksandra Pavliv's research focuses on the biochemical and cellular mechanisms underlying autism spectrum disorder (ASD). Her work has investigated evidence of oxidative damage and inflammation in the brains of individuals with ASD, often correlating these findings with altered glutathione redox status. Pavliv has also explored metabolic imbalances associated with methylation dysregulation and oxidative damage in children with ASD.

Her research group has examined the efficacy of specific treatments, such as methylcobalamin and folinic acid, on glutathione redox status in children with ASD. Studies have also delved into cellular and mitochondrial glutathione redox imbalances in lymphoblastoid cells derived from children with ASD, and how oxidative stress can induce mitochondrial dysfunction in these cell lines. Additionally, her work has touched upon the genetic factors influencing ASD, including research on functional polymorphisms in folate transport genes and their association with DNA hypomethylation in mothers of children with ASD.

Pavliv has collaborated with several researchers at the University of Arkansas for Medical Sciences, including Craig Porter, D Sadler, Lillie Treas, and Shannon Rose, with whom she shares multiple publications. She is recognized as a highly cited researcher, with an h-index of 21 and over 2,500 citations across her 52 publications.

Metrics

h-index: 20
Publications: 31
Citations: 2,526

Positions

Research Assistant publications 2005–2025

University of Arkansas for Medical Sciences Institution web page

Selected Publications

Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform (2025)

Physiological Reports DOI OpenAlex
Maternal metabolic profile predicts high or low risk of an autism pregnancy outcome (2018)

Research in Autism 34 citations DOI OpenAlex
Liver steatosis and redox status alterations in obese Zucker rats (2017)

The FASEB Journal 1 citation DOI OpenAlex
Short-term dietary methionine supplementation affects one-carbon metabolism and DNA methylation in the mouse gut and leads to altered microbiome profiles, barrier function, gene expression and histomorphology (2017)

Genes & Nutrition 64 citations DOI OpenAlex
Effects of Obesity on Pro-Oxidative Conditions and DNA Damage in Liver of DMBA-Induced Mammary Carcinogenesis Models (2017)

Metabolites 8 citations DOI OpenAlex
Overexpression of LINE-1 Retrotransposons in Autism Brain (2017)

Molecular Neurobiology 95 citations DOI OpenAlex
Effects of local irradiation combined with sunitinib on early remodeling, mitochondria, and oxidative stress in the rat heart (2016)

Radiotherapy and Oncology 26 citations DOI OpenAlex
Radiation-induced changes in DNA methylation of repetitive elements in the mouse heart (2016)

Mutation research. Fundamental and molecular mechanisms of mutagenesis 62 citations DOI OpenAlex
A Tocotrienol-Enriched Formulation Protects against Radiation-Induced Changes in Cardiac Mitochondria without Modifying Late Cardiac Function or Structure (2015)

Radiation Research 32 citations DOI OpenAlex
Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum (2014)

Translational Psychiatry 81 citations DOI OpenAlex
Complex epigenetic regulation of Engrailed-2 (EN-2) homeobox gene in the autism cerebellum (2013)

Translational Psychiatry 100 citations DOI OpenAlex
Dietary Intake and Plasma Levels of Choline and Betaine in Children with Autism Spectrum Disorders (2013)

Autism Research and Treatment 47 citations DOI OpenAlex
Effectiveness of Methylcobalamin and Folinic Acid Treatment on Adaptive Behavior in Children with Autistic Disorder Is Related to Glutathione Redox Status (2013)

Autism Research and Treatment 87 citations DOI OpenAlex
Evidence of oxidative damage and inflammation associated with low glutathione redox status in the autism brain (2012)

Translational Psychiatry 485 citations DOI OpenAlex
Metabolic Imbalance Associated with Methylation Dysregulation and Oxidative Damage in Children with Autism (2011)

Journal of Autism and Developmental Disorders 254 citations DOI OpenAlex