D
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Biography and Research Information
OverviewAI-generated summary
D Sadler's research investigates the interplay between environmental factors, metabolism, and physiological responses, with a focus on energy expenditure and vascular health. Studies have examined how housing temperature influences whole-body energy expenditure and thermogenic capacity in mice, and the effects of protonophore treatment on energy expenditure at thermoneutrality. Work has also explored the impact of exercise-induced shear rate on endothelial cell phosphorylation and the role of cocoa flavanols in improving pulmonary oxygen uptake kinetics and exercise tolerance in sedentary adults. Additionally, research has touched upon the influence of parental cardiorespiratory fitness on early life energetics and metabolic health, and maternal health factors on infant cardiac development. Sadler's work has resulted in 38 publications and has a h-index of 4, with recent activity noted in 2025. Collaborations include researchers such as Craig Porter, Elisabet Børsheim, Oleksandra Pavliv, and Shannon Rose at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 4
- Publications: 39
- Citations: 64
Selected Publications
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Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform (2025)
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Shared and distinct adaptations to early‐life exercise training based on inborn fitness (2025)
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Shared and distinct adaptations to early-life exercise training based on inborn fitness (2024)
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Protonophore treatment augments energy expenditure in mice housed at thermoneutrality (2024)
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Parental cardiorespiratory fitness influences early life energetics and metabolic health (2023)
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A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice (2022)
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Housing Temperature Alters Energy Expenditure and Adipose Tissue Bioenergetics in Mice (2022)
Collaboration Network
Top Collaborators
Craig Porter
Arkansas Children's Hospital
9 shared publications
In database
- A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice
- Parental cardiorespiratory fitness influences early life energetics and metabolic health
- Protonophore treatment augments energy expenditure in mice housed at thermoneutrality
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
- Maternal hemoglobin A1c and left ventricular hypertrophy in infants of mothers with pre-gestational diabetes
Showing 5 of 9 shared publications
Lillie Treas
Arkansas Children's Hospital (US)
8 shared publications
- A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice
- Parental cardiorespiratory fitness influences early life energetics and metabolic health
- Protonophore treatment augments energy expenditure in mice housed at thermoneutrality
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
- Housing Temperature Alters Energy Expenditure and Adipose Tissue Bioenergetics in Mice
Showing 5 of 8 shared publications
James D. Sikes
Arkansas Children's Nutrition Center (US)
5 shared publications
- A modest change in housing temperature alters whole body energy expenditure and adipocyte thermogenic capacity in mice
- Parental cardiorespiratory fitness influences early life energetics and metabolic health
- Protonophore treatment augments energy expenditure in mice housed at thermoneutrality
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
- Shared and distinct adaptations to early-life exercise training based on inborn fitness
Elisabet Børsheim
Arkansas Children's Hospital
5 shared publications
In database
- Parental cardiorespiratory fitness influences early life energetics and metabolic health
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
- Mitochondrial Respiratory Function in Human Platelets: Influence of Sample Preparation, Assay Buffer and Instrumental Platform
- Shared and distinct adaptations to early-life exercise training based on inborn fitness
- Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform
Richard Draijer
Unilever Foods Innovation Centre (NL)
4 shared publications
- (–)‐Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells
- Cocoa-flavanols enhance moderate-intensity pulmonary $$\dot{V}{\text{O}}_{2}$$ kinetics but not exercise tolerance in sedentary middle-aged adults
- (–)-Epicatechin alters reactive oxygen and nitrogen species production independent of mitochondrial respiration in human vascular endothelial cells
- Replicative ageing perturbs the metabolic signature of murine C <sub>2</sub> C <sub>12</sub> skeletal myotubes
Claire E. Stewart
Liverpool John Moores University (GB)
4 shared publications
- (–)‐Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells
- Cocoa-flavanols enhance moderate-intensity pulmonary $$\dot{V}{\text{O}}_{2}$$ kinetics but not exercise tolerance in sedentary middle-aged adults
- (–)-Epicatechin alters reactive oxygen and nitrogen species production independent of mitochondrial respiration in human vascular endothelial cells
- Replicative ageing perturbs the metabolic signature of murine C <sub>2</sub> C <sub>12</sub> skeletal myotubes
Helen Jones
Liverpool John Moores University (GB)
4 shared publications
- (–)‐Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells
- Cocoa-flavanols enhance moderate-intensity pulmonary $$\dot{V}{\text{O}}_{2}$$ kinetics but not exercise tolerance in sedentary middle-aged adults
- (–)-Epicatechin alters reactive oxygen and nitrogen species production independent of mitochondrial respiration in human vascular endothelial cells
- Replicative ageing perturbs the metabolic signature of murine C <sub>2</sub> C <sub>12</sub> skeletal myotubes
Dick H. J. Thijssen
Liverpool John Moores University (GB)
4 shared publications
- (–)‐Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells
- Cocoa-flavanols enhance moderate-intensity pulmonary $$\dot{V}{\text{O}}_{2}$$ kinetics but not exercise tolerance in sedentary middle-aged adults
- (–)-Epicatechin alters reactive oxygen and nitrogen species production independent of mitochondrial respiration in human vascular endothelial cells
- Replicative ageing perturbs the metabolic signature of murine C <sub>2</sub> C <sub>12</sub> skeletal myotubes
Jonathan Barlow
University of Birmingham (GB)
3 shared publications
- (–)‐Epicatechin Alters Reactive Oxygen and Nitrogen Species Production Independent of Mitochondrial Respiration in Human Vascular Endothelial Cells
- (–)-Epicatechin alters reactive oxygen and nitrogen species production independent of mitochondrial respiration in human vascular endothelial cells
- Replicative ageing perturbs the metabolic signature of murine C <sub>2</sub> C <sub>12</sub> skeletal myotubes
Taylor Ross
Arkansas Children's Nutrition Center (US)
3 shared publications
- Parental cardiorespiratory fitness influences early life energetics and metabolic health
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
- Shared and distinct adaptations to early-life exercise training based on inborn fitness
Steven L. Britton
University of Michigan–Ann Arbor (US)
3 shared publications
- Parental cardiorespiratory fitness influences early life energetics and metabolic health
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
- Shared and distinct adaptations to early-life exercise training based on inborn fitness
Oleksandra Pavliv
Arkansas Children's Hospital
2 shared publications
In database
- Mitochondrial Respiratory Function in Human Platelets: Influence of Sample Preparation, Assay Buffer and Instrumental Platform
- Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform
Matthew Cotter
Arkansas Children's Hospital (US)
2 shared publications
- Mitochondrial Respiratory Function in Human Platelets: Influence of Sample Preparation, Assay Buffer and Instrumental Platform
- Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform
Shannon Rose
Arkansas Children's Hospital
2 shared publications
In database
- Mitochondrial Respiratory Function in Human Platelets: Influence of Sample Preparation, Assay Buffer and Instrumental Platform
- Mitochondrial respiratory function in human platelets: Influence of sample preparation, assay buffer, and instrumental platform
Lauren G. Koch
University of Toledo (US)
2 shared publications
- Parental cardiorespiratory fitness influences early life energetics and metabolic health
- Shared and distinct adaptations to early‐life exercise training based on inborn fitness
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