Robert P. Felton

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NCTR

Also affiliated: United States Food and Drug Administration (1989–2024)

10 h-index 19 pubs 688 cited

Research Areas

Biomedical Subjects

OverviewAI-generated summary

Robert P. Felton's research focuses on toxicological evaluations across various exposure routes and species. He has investigated the toxicity of high-molecular-weight polyethylene glycols and brominated vegetable oil in Sprague Dawley rats. Felton has also conducted inhalation toxicity studies of NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone) in Sprague-Dawley rats, including a 90-day nose-only inhalation toxicity study and a 14-day study assessing Haber's Rule. His work also extends to dermal carcinogenicity bioassays, such as a two-year study of triclosan in B6C3F1 mice. Felton has contributed to the development and evaluation of alternative skin models for dermal absorption studies, including excised human skin and other in vitro human skin models for permeation testing. His research collaborations at the National Center for Toxicological Research include shared publications with Mackean P. Maisha, Frederick A. Beland, Ralph E. Patton, and Matthew Bryant. Felton's scholarship metrics include an h-index of 10 and 19 total publications with 661 citations.

Metrics

h-index: 10
Publications: 19
Citations: 688

Selected Publications

P19-17 Use of diverse human skin models in in vitro skin permeation testing of dermatological ingredients (2024)

Toxicology Letters DOI OpenAlex
Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice (2023)

Archives of Toxicology 1 citation DOI OpenAlex
Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro (2023)

Toxicology in Vitro 19 citations DOI OpenAlex
Toxicological evaluation of brominated vegetable oil in Sprague Dawley rats (2022)

Food and Chemical Toxicology 5 citations DOI OpenAlex
Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats (2022)

Toxicology Letters 22 citations DOI OpenAlex
90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)

Food and Chemical Toxicology 6 citations DOI OpenAlex
14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)

Toxicological Sciences 7 citations DOI OpenAlex
A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results (2019)

Food and Chemical Toxicology 62 citations DOI OpenAlex
From the Cover: Aloin, a Component of the Aloe Vera Plant Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344/N Male Rats (2017)

Toxicological Sciences 58 citations DOI OpenAlex
Photo‐co‐carcinogenesis of Topically Applied Retinyl Palmitate in SKH‐1 Hairless Mice (2017)

Photochemistry and Photobiology 4 citations DOI OpenAlex
A comment on the discussion and application of statistical methods in Mandrup <i>et al</i>. Low‐dose effects of bisphenol A on mammary gland development in rats (Andrology 4: 673–683, 2016) (2016)

Andrology 1 citation DOI OpenAlex
Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study (2016)

Food and Chemical Toxicology 55 citations DOI OpenAlex
Differential Effects of Silver Nanoparticles and Silver Ions on Tissue Accumulation, Distribution, and Toxicity in the Sprague Dawley Rat Following Daily Oral Gavage Administration for 13 Weeks (2016)

Toxicological Sciences 135 citations DOI OpenAlex
Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90 (2014)

Toxicological Sciences 165 citations DOI OpenAlex
Clear Evidence of Carcinogenic Activity by a Whole-Leaf Extract of Aloe barbadensis Miller (Aloe vera) in F344/N Rats (2012)

Toxicological Sciences 96 citations DOI OpenAlex