Robert P. Felton
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Researcher
Also affiliated: United States Food and Drug Administration (2017–2024)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Robert P. Felton's research focuses on toxicological evaluations across various exposure routes and species. He has investigated the toxicity of high-molecular-weight polyethylene glycols and brominated vegetable oil in Sprague Dawley rats. Felton has also conducted inhalation toxicity studies of NNK (4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone) in Sprague-Dawley rats, including a 90-day nose-only inhalation toxicity study and a 14-day study assessing Haber's Rule. His work also extends to dermal carcinogenicity bioassays, such as a two-year study of triclosan in B6C3F1 mice. Felton has contributed to the development and evaluation of alternative skin models for dermal absorption studies, including excised human skin and other in vitro human skin models for permeation testing. His research collaborations at the National Center for Toxicological Research include shared publications with Mackean P. Maisha, Frederick A. Beland, Ralph E. Patton, and Matthew Bryant. Felton's scholarship metrics include an h-index of 10 and 19 total publications with 661 citations.
Metrics
- h-index: 10
- Publications: 19
- Citations: 677
Selected Publications
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P19-17 Use of diverse human skin models in in vitro skin permeation testing of dermatological ingredients (2024)
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Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice (2023)
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Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro (2023)
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Toxicological evaluation of brominated vegetable oil in Sprague Dawley rats (2022)
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Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats (2022)
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90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats (2021)
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14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats (2021)
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A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results (2019)
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From the Cover: Aloin, a Component of the Aloe Vera Plant Leaf, Induces Pathological Changes and Modulates the Composition of Microbiota in the Large Intestines of F344/N Male Rats (2017)
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Photo‐co‐carcinogenesis of Topically Applied Retinyl Palmitate in SKH‐1 Hairless Mice (2017)
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A comment on the discussion and application of statistical methods in Mandrup <i>et al</i>. Low‐dose effects of bisphenol A on mammary gland development in rats (Andrology 4: 673–683, 2016) (2016)
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Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study (2016)
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Differential Effects of Silver Nanoparticles and Silver Ions on Tissue Accumulation, Distribution, and Toxicity in the Sprague Dawley Rat Following Daily Oral Gavage Administration for 13 Weeks (2016)
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Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90 (2014)
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Clear Evidence of Carcinogenic Activity by a Whole-Leaf Extract of Aloe barbadensis Miller (Aloe vera) in F344/N Rats (2012)
Collaboration Network
Top Collaborators
- Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- P19-17 Use of diverse human skin models in in vitro skin permeation testing of dermatological ingredients
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- Parallel evaluation of alternative skin barrier models and excised human skin for dermal absorption studies in vitro
- Toxicological evaluation of brominated vegetable oil in Sprague Dawley rats
- Two-year dermal carcinogenicity bioassay of triclosan in B6C3F1 mice
- Toxicity of high-molecular-weight polyethylene glycols in Sprague Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
- 14-Day Nose-Only Inhalation Toxicity and Haber’s Rule Study of NNK in Sprague-Dawley Rats
- 90-day nose-only inhalation toxicity study of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) in Sprague-Dawley rats
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