Sendurai A. Mani Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Professor
John Brown University
faculty
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Biography and Research Information
OverviewAI-generated summary
Professor Sendurai A. Mani's laboratory explores the complex biology underpinning cancer metastasis, therapy resistance, and tumor relapse. His research aims to identify new therapeutic targets by elucidating cancer-related molecular mechanisms. With expertise in cancer genomics and diagnostics, Dr. Mani investigates areas such as FOXO transcription factor regulation, epigenetics, and DNA methylation. His recent work, including publications as recently as 2025, reflects an ongoing commitment to understanding and combating cancer progression.
Metrics
- h-index: 62
- Publications: 283
- Citations: 30,649
Selected Publications
- Mutations in MLL3 promote breast cancer progression via HIF1α-dependent intratumoral recruitment and differentiation of regulatory T cells (2025) DOI
- 491 | SPATIAL TRANSCRIPTOMICS OF FOLLICULAR AND MARGINAL ZONE LYMPHOMAS IDENTIFIES DOMAINS OF CD8+ T CELL RECRUITMENT AND EXCLUSION (2025) DOI
- Acquired resistance to molecularly targeted therapies for cancer (2025) DOI
- β-Catenin Drives the FOXC2-Mediated Epithelial–Mesenchymal Transition and Acquisition of Stem Cell Properties (2025) DOI
- Worldwide Innovative Network (WIN) Consortium in Personalized Cancer Medicine: Bringing next-generation precision oncology to patients (2025) DOI
- Accumulation of CD38 in Hybrid Epithelial/Mesenchymal Cells Promotes Immune Remodeling and Metastasis in Breast Cancer (2025) DOI
- The Cancer Chimera: Impact of Vimentin and Cytokeratin Co-Expression in Hybrid Epithelial/Mesenchymal Cancer Cells on Tumor Plasticity and Metastasis (2024) DOI
- Therapeutic insights for the aggressive subset of high-grade gliomas (HGG) driven by chromosome 1q32 <i>MDM4-containing</i> amplicon and unmethylated <i>MGMT</i>. (2024) DOI
- Spatial and Temporal Relationship between Epithelial–Mesenchymal Transition (EMT) and Stem Cells in Cancer (2024) DOI
- Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas (2023) DOI
- Proactive and reactive roles of TGF-β in cancer (2023) DOI
- Abstract 2454: Identification of colorectal cancer stem cells from single cell RNA sequencing (2023) DOI
- Supplementary Figures 1-2 from Enrichment of a Population of Mammary Gland Cells that Form Mammospheres and Have <i>In vivo</i> Repopulating Activity (2023) DOI
- Supplementary Figure Legends 1-2 from Enrichment of a Population of Mammary Gland Cells that Form Mammospheres and Have <i>In vivo</i> Repopulating Activity (2023) DOI
- Supplementary Figure Legends 1-2 from Enrichment of a Population of Mammary Gland Cells that Form Mammospheres and Have <i>In vivo</i> Repopulating Activity (2023) DOI
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