Shobanbabu Bommagani
Sourced from institutional research profiles (UAMS TRI or ARA).
Researcher
Also affiliated: Indian Institute of Chemical Technology (2017)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Shobanbabu Bommagani's research program focuses on drug discovery and development, particularly in the areas of cancer treatment and infectious diseases. His work involves investigating the molecular structure of therapeutic agents and their relationship to biological activity, often employing cell-based assays and structural biology techniques. Bommagani has published research on potential anti-cancer compounds, including sesquiterpenes, and has investigated the mechanisms of action for novel therapeutic strategies. His recent publications also include work on targeting viral proteins, such as the SARS-CoV-2 Nsp3 macrodomain, and evaluating the toxicity of drug delivery systems. Bommagani collaborates with researchers at the University of Arkansas for Medical Sciences, including Darin E. Jones, Abdul H. Khan, Abhishek Mishra, and John D. Imig. His scholarship metrics include an h-index of 7, with 36 total publications and 264 citations. He remains actively publishing, with his most recent work appearing in 2025.
Metrics
- h-index: 7
- Publications: 36
- Citations: 271
Selected Publications
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EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage (2025)
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Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors (2021)
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Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone (2021)
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Oxone®-Mediated TEMPO-Oxidized Cellulose Nanomaterials form I and form II (2020)
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A Facile Microwave Assisted TEMPO/NaOCl/Oxone (KHSO<sub>5</sub>) Mediated Micron Cellulose Oxidation Procedure: Preparation of Two Nano TEMPO‐Cellulose Forms (2019)
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Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M1 – M5 muscarinic acetylcholine receptors (2018)
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A novel tetrazole analogue of resveratrol is a potent anticancer agent (2018)
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Crystal structure of 13-(<i>E</i>)-(2-aminobenzylidene)parthenolide (2018)
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Attempts towards the synthesis of mupirocin-H (2017)
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Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells (2017)
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A novel and efficient tributyltin azide-mediated synthesis of 1H-tetrazolylstilbenes from cyanostilbenes (2016)
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Crystal structure of (<i>E</i>)-13-(pyrimidin-5-yl)parthenolide (2015)
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Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin (2015)
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Synthesis of O- and N-alkylated products of 1,2,3,4-tetrahydrobenzo[c][2,7]naphthyrin-5(6H)-one (2015)
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Comparison of crystal structures of 4-(benzo[<i>b</i>]thiophen-2-yl)-5-(3,4,5-trimethoxyphenyl)-2<i>H</i>-1,2,3-triazole and 4-(benzo[<i>b</i>]thiophen-2-yl)-2-methyl-5-(3,4,5-trimethoxyphenyl)-2<i>H</i>-1,2,3-triazole (2014)
Grants & Funding
As listed on this researcher's institutional profile.
- Targeting DNA ligase 1 in Ovarian Cancer NIH/Nat. Cancer Institute via University of New Mexico
Collaboration Network
Top Collaborators
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage
- Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone
- Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone
- Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone
- Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone
- Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
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