Match tier Institution-verified
Presence Current · Arkansas
Last published 2025
Sources Institutional record
Refreshed 2026-08-08

Shobanbabu Bommagani

Sourced from institutional research profiles (UAMS TRI or ARA).

Researcher

Also affiliated: Indian Institute of Chemical Technology (2017)

Faculty Researcher

7 h-index 36 pubs 271 cited

  • Humans
  • Structure-Activity Relationship
  • Antineoplastic Agents
  • Dose-Response Relationship, Drug
  • Molecular Structure
  • Cell Line, Tumor
  • Drug Screening Assays, Antitumor
  • Cell Proliferation
  • Sesquiterpenes
  • Animals
  • Sorafenib
  • Podocytes
  • Mesangial Cells
  • Protein Domains
  • SARS-CoV-2

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Biography and Research Information

OverviewAI-generated summary

Shobanbabu Bommagani's research program focuses on drug discovery and development, particularly in the areas of cancer treatment and infectious diseases. His work involves investigating the molecular structure of therapeutic agents and their relationship to biological activity, often employing cell-based assays and structural biology techniques. Bommagani has published research on potential anti-cancer compounds, including sesquiterpenes, and has investigated the mechanisms of action for novel therapeutic strategies. His recent publications also include work on targeting viral proteins, such as the SARS-CoV-2 Nsp3 macrodomain, and evaluating the toxicity of drug delivery systems. Bommagani collaborates with researchers at the University of Arkansas for Medical Sciences, including Darin E. Jones, Abdul H. Khan, Abhishek Mishra, and John D. Imig. His scholarship metrics include an h-index of 7, with 36 total publications and 264 citations. He remains actively publishing, with his most recent work appearing in 2025.

Metrics

  • h-index: 7
  • Publications: 36
  • Citations: 271

Selected Publications

  • EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage (2025)
    Biomolecules DOI OpenAlex
  • Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors (2021)
    Progress in Biophysics and Molecular Biology 63 citations DOI OpenAlex
  • Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone (2021)
    Toxicology Reports 2 citations DOI OpenAlex
  • Oxone®-Mediated TEMPO-Oxidized Cellulose Nanomaterials form I and form II (2020)
    Molecules 6 citations DOI OpenAlex
  • A Facile Microwave Assisted TEMPO/NaOCl/Oxone (KHSO<sub>5</sub>) Mediated Micron Cellulose Oxidation Procedure: Preparation of Two Nano TEMPO‐Cellulose Forms (2019)
    Starch - Stärke 7 citations DOI OpenAlex
  • Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M1 – M5 muscarinic acetylcholine receptors (2018)
    Bioorganic & Medicinal Chemistry Letters DOI OpenAlex
  • A novel tetrazole analogue of resveratrol is a potent anticancer agent (2018)
    Bioorganic & Medicinal Chemistry Letters 40 citations DOI OpenAlex
  • Crystal structure of 13-(<i>E</i>)-(2-aminobenzylidene)parthenolide (2018)
    Acta Crystallographica Section E Crystallographic Communications DOI OpenAlex
  • Attempts towards the synthesis of mupirocin-H (2017)
    ARKIVOC 2 citations DOI OpenAlex
  • Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells (2017)
    European Journal of Medicinal Chemistry 29 citations DOI OpenAlex
  • A novel and efficient tributyltin azide-mediated synthesis of 1H-tetrazolylstilbenes from cyanostilbenes (2016)
    Tetrahedron Letters 14 citations DOI OpenAlex
  • Crystal structure of (<i>E</i>)-13-(pyrimidin-5-yl)parthenolide (2015)
    Acta Crystallographica Section E Crystallographic Communications 1 citation DOI OpenAlex
  • Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin (2015)
    MedChemComm 47 citations DOI OpenAlex
  • Synthesis of O- and N-alkylated products of 1,2,3,4-tetrahydrobenzo[c][2,7]naphthyrin-5(6H)-one (2015)
    Tetrahedron Letters 3 citations DOI OpenAlex
  • Comparison of crystal structures of 4-(benzo[<i>b</i>]thiophen-2-yl)-5-(3,4,5-trimethoxyphenyl)-2<i>H</i>-1,2,3-triazole and 4-(benzo[<i>b</i>]thiophen-2-yl)-2-methyl-5-(3,4,5-trimethoxyphenyl)-2<i>H</i>-1,2,3-triazole (2014)
    Acta Crystallographica Section E Structure Reports Online 6 citations DOI OpenAlex

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Grants & Funding

As listed on this researcher's institutional profile.

  • Targeting DNA ligase 1 in Ovarian Cancer NIH/Nat. Cancer Institute via University of New Mexico

Collaboration Network

27 Collaborators 6 Institutions 2 Countries

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