Shobanbabu Bommagani
Sourced from institutional research profiles (UAMS TRI or ARA).
Ph.D.
Also affiliated: Indian Institute of Chemical Technology (2017)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Shobanbabu Bommagani's research program focuses on drug discovery and development, particularly in the areas of cancer treatment and infectious diseases. His work involves investigating the molecular structure of therapeutic agents and their relationship to biological activity, often employing cell-based assays and structural biology techniques. Bommagani has published research on potential anti-cancer compounds, including sesquiterpenes, and has investigated the mechanisms of action for novel therapeutic strategies. His recent publications also include work on targeting viral proteins, such as the SARS-CoV-2 Nsp3 macrodomain, and evaluating the toxicity of drug delivery systems. Bommagani collaborates with researchers at the University of Arkansas for Medical Sciences, including Darin E. Jones, Abdul H. Khan, Abhishek Mishra, and John D. Imig. His scholarship metrics include an h-index of 7, with 36 total publications and 264 citations. He remains actively publishing, with his most recent work appearing in 2025.
Metrics
- h-index: 9
- Publications: 38
- Citations: 307
Positions
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Ph.D. publications 2013–2025University of Arkansas for Medical Sciences Institution web page
Selected Publications
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EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage (2025)
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Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors (2021)
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Evaluation of bone and kidney toxicity of BT2-peg2, a potential carrier for the targeted delivery of antibiotics to bone (2021)
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Oxone®-Mediated TEMPO-Oxidized Cellulose Nanomaterials form I and form II (2020)
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A Novel Microtubule-Binding Drug Attenuates and Reverses Protein Aggregation in Animal Models of Alzheimer’s Disease (2019)
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A Facile Microwave Assisted TEMPO/NaOCl/Oxone (KHSO5) Mediated Micron Cellulose Oxidation Procedure: Preparation of Two Nano TEMPO‐Cellulose Forms (2019)
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Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M1 – M5 muscarinic acetylcholine receptors (2018)
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A novel tetrazole analogue of resveratrol is a potent anticancer agent (2018)
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Crystal structure of 13-(E)-(2-aminobenzylidene)parthenolide (2018)
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Evaluation of morphine‐like effects of the mixed mu/delta agonist morphine‐6‐O‐sulfate in rats: Drug discrimination and physical dependence (2018)
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Attempts towards the synthesis of mupirocin-H (2017)
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Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells (2017)
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A novel and efficient tributyltin azide-mediated synthesis of 1H-tetrazolylstilbenes from cyanostilbenes (2016)
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Crystal structure of (E)-13-(pyrimidin-5-yl)parthenolide (2015)
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Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin (2015)
Grants & Funding
As listed on this researcher's institutional profile.
- Targeting DNA ligase 1 in Ovarian Cancer NIH/Nat. Cancer Institute via University of New Mexico
Collaboration Network
Top Collaborators
- Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin
- A novel tetrazole analogue of resveratrol is a potent anticancer agent
- Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells
- Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression
- Synthesis and evaluation of a series of quinolinyl trans-cyanostilbene analogs as anticancer agents
Showing 5 of 16 shared publications
- Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin
- A novel tetrazole analogue of resveratrol is a potent anticancer agent
- Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells
- Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression
- Synthesis and evaluation of a series of quinolinyl trans-cyanostilbene analogs as anticancer agents
Showing 5 of 15 shared publications
- Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin
- Indole carboxylic acid esters of melampomagnolide B are potent anticancer agents against both hematological and solid tumor cells
- Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression
- Synthesis and evaluation of a series of quinolinyl trans-cyanostilbene analogs as anticancer agents
- Crystal structure of (E)-13-{4-[(Z)-2-cyano-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl}parthenolide methanol hemisolvate
Showing 5 of 7 shared publications
- Comparison of crystal structures of 4-(benzo[b]thiophen-2-yl)-5-(3,4,5-trimethoxyphenyl)-2H-1,2,3-triazole and 4-(benzo[b]thiophen-2-yl)-2-methyl-5-(3,4,5-trimethoxyphenyl)-2H-1,2,3-triazole
- Crystal structure of 4,5-bis(3,4,5-trimethoxyphenyl)-2H-1,2,3-triazole methanol monosolvate
- Crystal structure of (E)-13-{4-[(Z)-2-cyano-2-(3,4,5-trimethoxyphenyl)ethenyl]phenyl}parthenolide methanol hemisolvate
- 13-(N,N-Dimethylamino)micheliolide 0.08-hydrate
- Crystal structure of (E)-13-(pyrimidin-5-yl)parthenolide
Showing 5 of 7 shared publications
- Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin
- Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression
- Comparison of crystal structures of 4-(benzo[b]thiophen-2-yl)-5-(3,4,5-trimethoxyphenyl)-2H-1,2,3-triazole and 4-(benzo[b]thiophen-2-yl)-2-methyl-5-(3,4,5-trimethoxyphenyl)-2H-1,2,3-triazole
- Crystal structure of 4,5-bis(3,4,5-trimethoxyphenyl)-2H-1,2,3-triazole methanol monosolvate
- Synthesis of O- and N-alkylated products of 1,2,3,4-tetrahydrobenzo[c][2,7]naphthyrin-5(6H)-one
- Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M1 – M5 muscarinic acetylcholine receptors
- Synthesis of O- and N-alkylated products of 1,2,3,4-tetrahydrobenzo[c][2,7]naphthyrin-5(6H)-one
- Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M1 – M5 muscarinic acetylcholine receptors
- Synthesis of O- and N-alkylated products of 1,2,3,4-tetrahydrobenzo[c][2,7]naphthyrin-5(6H)-one
- Muscarinic agonist, (±)-quinuclidin-3-yl-(4-fluorophenethyl)(phenyl)carbamate: High affinity, but low subtype selectivity for human M1 – M5 muscarinic acetylcholine receptors
- Synthesis and evaluation of a series of resveratrol analogues as potent anti-cancer agents that target tubulin
- A novel tetrazole analogue of resveratrol is a potent anticancer agent
- A Facile Microwave Assisted TEMPO/NaOCl/Oxone (KHSO5) Mediated Micron Cellulose Oxidation Procedure: Preparation of Two Nano TEMPO‐Cellulose Forms
- Oxone®-Mediated TEMPO-Oxidized Cellulose Nanomaterials form I and form II
- A Facile Microwave Assisted TEMPO/NaOCl/Oxone (KHSO5) Mediated Micron Cellulose Oxidation Procedure: Preparation of Two Nano TEMPO‐Cellulose Forms
- Oxone®-Mediated TEMPO-Oxidized Cellulose Nanomaterials form I and form II
- A Facile Microwave Assisted TEMPO/NaOCl/Oxone (KHSO5) Mediated Micron Cellulose Oxidation Procedure: Preparation of Two Nano TEMPO‐Cellulose Forms
- Oxone®-Mediated TEMPO-Oxidized Cellulose Nanomaterials form I and form II
- Targeting SARS-CoV-2 Nsp3 macrodomain structure with insights from human poly(ADP-ribose) glycohydrolase (PARG) structures with inhibitors
- EET-Based Therapeutics Mitigate Sorafenib-Associated Glomerular Cell Damage
- Synthesis of O- and N-alkylated products of 1,2,3,4-tetrahydrobenzo[c][2,7]naphthyrin-5(6H)-one
- Heck products of parthenolide and melampomagnolide-B as anticancer modulators that modify cell cycle progression
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