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Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
V
Vijayalakshmi Sridharan
High Impact
Researcher
Also affiliated: Medical University of South Carolina (2006–2009); Georgetown University (2024); Chettinad Academy of Research and Education (2025); University of Arkansas Medical Center (2018); Georgetown University Medical Center (2024); Moffitt Cancer Center (2012); MUSC Hollings Cancer Center (2007); Central Arkansas Veterans Healthcare System (2012); G. Kuppuswamy Naidu Memorial Hospital (2024); China National Building Materials Group (China) (2009); National Institute of Immunology (2004–2005); Charité - Universitätsmedizin Berlin (2012)
Faculty Researcher
28 h-index
101 pubs
2,533 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Vijayalakshmi Sridharan's research focuses on the physiological and structural effects of radiation on the heart and other organs. Her work investigates radiation-induced cardiac dysfunction, including its underlying mechanisms and potential preventative strategies. Sridharan has examined the effects of different types of radiation, such as protons and simulated galactic cosmic radiation, on cardiac function and structure in animal models, primarily mice and rats.
Her publications explore various factors influencing radiation's impact, including sex-dependent effects and the role of specific genes like TLR4 and M2. Sridharan also investigates potential therapeutic interventions, such as the use of dantrolene to prevent doxorubicin-induced lymphostasis and the application of metabolomics for predicting radiation-induced cardiac dysfunction. She has collaborated with several researchers at the University of Arkansas for Medical Sciences, including Marjan Boerma, Martin Hauer-Jensen, Benjamin J. Lieblong, and Reid D. Landes, on numerous shared publications.
Sridharan's scholarship metrics include an h-index of 27, with over 101 publications and 2,470 citations. She is recognized as a highly cited researcher, indicating a significant impact in her field. Her recent activity and publication record demonstrate ongoing engagement with these research areas.
Metrics
- h-index: 28
- Publications: 101
- Citations: 2,533
Selected Publications
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Changes in gut, microbiome, and cognition after doxorubicin, cyclophosphamide, and paclitaxel chemotherapy treatment (2026)
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Implications of cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy on hippocampal-dependent cognition and gut microbiome (2025)
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Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice (2025)
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Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming (2025)
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Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading (2024)
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Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma (2024)
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Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma (2024)
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A pooled analysis of nine studies in one institution to assess effects of whole heart irradiation in rat models (2023)
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TLR4—A Pertinent Player in Radiation-Induced Heart Disease? (2023)
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Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction (2023)
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Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model (2023)
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Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart (2023)
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Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart (2023)
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Low dose space radiation-induced effects on the mouse retina and blood-retinal barrier integrity (2022)
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Small animal models of localized heart irradiation (2022)
Collaboration Network
Top Collaborators
Marjan Boerma
University of Arkansas for Medical Sciences
19 shared publications
In database
- TLR4—A Pertinent Player in Radiation-Induced Heart Disease?
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- The M2 Gene Is a Determinant of Reovirus-Induced Myocarditis
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart
Showing 5 of 19 shared publications
Yaoxiang Li
Georgetown University (US)
7 shared publications
- Longitudinal metabolic alterations in plasma of rats exposed to low doses of high linear energy transfer radiation
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Short-term metabolic disruptions in urine of mouse models following exposure to low doses of oxygen ion radiation
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
Showing 5 of 7 shared publications
Amrita K. Cheema
Georgetown University (US)
7 shared publications
- Longitudinal metabolic alterations in plasma of rats exposed to low doses of high linear energy transfer radiation
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Short-term metabolic disruptions in urine of mouse models following exposure to low doses of oxygen ion radiation
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
Showing 5 of 7 shared publications
Reid D. Landes
University of Arkansas for Medical Sciences
6 shared publications
In database
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart
- Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
Showing 5 of 6 shared publications
Ashley Nemec-Bakk
University of Arkansas for Medical Sciences
6 shared publications
In database
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart
- Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading
Showing 5 of 6 shared publications
Antiño R. Allen
University of Arkansas Medical Center
5 shared publications
In database
- Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart
- Low dose space radiation-induced effects on the mouse retina and blood-retinal barrier integrity
- Effects of 16O charged-particle irradiation on cognition, hippocampal morphology and mutagenesis in female mice
- Implications of cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy on hippocampal-dependent cognition and gut microbiome
- Changes in gut, microbiome, and cognition after doxorubicin, cyclophosphamide, and paclitaxel chemotherapy treatment
Meth Jayatilake
Georgetown University Medical Center (US)
5 shared publications
- Longitudinal metabolic alterations in plasma of rats exposed to low doses of high linear energy transfer radiation
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Short-term metabolic disruptions in urine of mouse models following exposure to low doses of oxygen ion radiation
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
Shivani Bansal
Georgetown University Medical Center (US)
5 shared publications
- Longitudinal metabolic alterations in plasma of rats exposed to low doses of high linear energy transfer radiation
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
Sunil Bansal
Georgetown University Medical Center (US)
4 shared publications
- Longitudinal metabolic alterations in plasma of rats exposed to low doses of high linear energy transfer radiation
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
Maohua Cao
4 shared publications
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
Preeti Singh
Rite Aid (United States) (US)
4 shared publications
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Effects of low-dose oxygen ions on cardiac function and structure in female C57BL/6J mice
- Mitigation of late cardiovascular effects of oxygen ion radiation by γ-tocotrienol in a mouse model
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
Kimberly J. Krager
University of Arkansas for Medical Sciences
4 shared publications
In database
- TLR4—A Pertinent Player in Radiation-Induced Heart Disease?
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Small animal models of localized heart irradiation
- Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart
José A. Fernández
Scripps Research Institute (US)
4 shared publications
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
John H. Griffin
Scripps Research Institute (US)
4 shared publications
- Sex-dependent effects of genetic upregulation of activated protein C on delayed effects of acute radiation exposure in the mouse heart, small intestine, and skin
- Urinary Metabolomics for the Prediction of Radiation-Induced Cardiac Dysfunction
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
- Genetic Upregulation of Activated Protein C Mitigates Delayed Effects of Acute Radiation Exposure in the Mouse Plasma
Igor Koturbash
University of Arkansas for Medical Sciences
4 shared publications
In database
- Effects of proton and oxygen ion irradiation on cardiovascular function and structure in a rabbit model
- Sex-specific effects on the heart from combined exposure to simulated galactic cosmic radiation and hindlimb unloading
- Long-term effects of combined exposures to simulated microgravity and galactic cosmic radiation on the mouse lung: sex-specific epigenetic reprogramming
- Exposure to a Single Dose of Space-Relevant Proton Radiation Alters the Intestinal One-Carbon Metabolism Pathway and Microbiome in Mice
Similar Researchers
Based on overlapping research topics
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University of Arkansas for Medical Sciences
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University of Arkansas – Fort Smith
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