Kimberly J. Krager Data-verified

Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.

High Impact

Researcher

UAMS

Last publication 2026 Last refreshed 2026-05-16

faculty

21 h-index 73 pubs 2,855 cited

Research Areas

Links

Lab Website Research Group

OverviewAI-generated summary

Kimberly J. Krager's research investigates the molecular mechanisms underlying bone loss and radiation-induced tissue damage, with a particular focus on mitochondrial function. Her work has explored the role of Sirt3 in age-related or estrogen deficiency-induced bone loss and the impact of transferrin receptor 1-mediated iron uptake on bone mass in mice. Krager has also studied the effects of ionizing radiation and simulated galactic cosmic rays on osteoclast mitochondria, metabolism, and bone density. Her research extends to understanding sex-dependent effects of radiation exposure on various tissues in mice and the activation of mitochondrial function in osteoclasts following radiation exposure.

Additional areas of Krager's investigation include the induction of ferroptosis in hepatocellular carcinoma cells via thiol oxidation by Parthenolide. She has published extensively in these areas, accumulating 71 publications and over 2,700 citations, with an h-index of 20. Krager maintains an active research group and collaborates with researchers at the University of Arkansas for Medical Sciences, including Nükhet Aykin-Burns, Ha-Neui Kim, Francesca V. LoBianco, and Brian Koss, with whom she has co-authored numerous publications.

Metrics

h-index: 21
Publications: 73
Citations: 2,855

Selected Publications

Beneficial effects of an indole derivative melatonin analogue in estrogen receptor positive breast cancer (2026)

DOI OpenAlex
SIRT3–IDH2 axis is a target of dietary fructose: implication of IDH2 as a key player in dietary carcinogen toxicity in mice colon (2025)

DOI OpenAlex
Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025)

1 citation DOI OpenAlex
Enhancing Rectal Cancer Radiosensitivity and Gut Protection through Methionine Restriction (2025)

DOI OpenAlex
SIRT3-IDH2 axis is a target of dietary fructose: implication of IDH2 as a key player in dietary carcinogen toxicity in mice colon (2025)

DOI OpenAlex
Tocotrienols Provide Radioprotection to Multiple Organ Systems through Complementary Mechanisms of Antioxidant and Signaling Effects (2023)

9 citations DOI OpenAlex
TLR4—A Pertinent Player in Radiation-Induced Heart Disease? (2023)

36 citations DOI OpenAlex
Abstract No. 106 Where are Women in Academic Interventional Radiology? (2023)

12 citations DOI OpenAlex
Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model (2023)

9 citations DOI OpenAlex
Effects of Whole and Partial Heart Irradiation on Collagen, Mast Cells, and Toll-like Receptor 4 in the Mouse Heart (2023)

3 citations DOI OpenAlex
Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model (2022)

DOI OpenAlex
Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model (2022)

DOI OpenAlex
Hematopoietic cytoplasmic adaptor protein Hem1 promotes osteoclast fusion and bone resorption in mice (2022)

5 citations DOI OpenAlex
Parthenolide induces rapid thiol oxidation that leads to ferroptosis in hepatocellular carcinoma cells (2022)

17 citations DOI OpenAlex
Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton (2022)

2 citations DOI OpenAlex