Antiño R. Allen

◆ ARA Academy Federal Grant PI High Impact

Professor

UAMS primary University of Arkansas

Also affiliated: San Francisco General Hospital (2012); Children's Hospital of Philadelphia (2022); University of California, San Francisco (2012–2013); University of Arkansas Medical Center (2014–2026); Pulmonary and Allergy Associates (2025); Spinal Injuries Center (2014); Clovis Oncology (United States) (2012); Global Brain Health Institute (2013); Neurological Surgery (2012–2015); Arkansas Department of Health (2014–2018); University of Rochester (2006)

Faculty Researcher

26 h-index 87 pubs 2,010 cited

Research Areas

Biomedical Subjects

Links

ORCID Lab Website UAMS TRI Profile

OverviewAI-generated summary

Antiño R. Allen's research program investigates the consequences of environmental stressors, such as space radiation and chemotherapy, on biological systems, with a particular focus on neuroprotection and cognitive function. Allen has received federal funding from the National Institutes of Health for two projects totaling $639,667. The first, funded by the National Cancer Institute, supports work on "MnBuOE as a Novel Chemosensitizer for Breast Cancer and Neuroprotector," with Allen serving as PI. The second grant, from the National Institute of General Medical Sciences, is for the "Initiative for Maximizing Student Development (IMSD)," with Allen as Co-PI. His work has led to 87 publications and garnered approximately 1,990 citations, with an h-index of 26.

Allen's recent publications explore a range of topics including the neuroprotective potential of sulforaphane and piperlongumine against chemotherapy-induced cognitive impairment, the implications of breast cancer chemotherapy on various organ systems, and the role of MnSOD mimetics in combating oxidative stress. His research also extends to the cellular mechanisms of ferroptosis in hepatocellular carcinoma cells, induced by parthenolide. Allen collaborates with researchers at the University of Arkansas for Medical Sciences, including Pilar Simmons and Taylor McElroy, and Nükhet Aykin‐Burns at the University of Arkansas at Fayetteville.

Metrics

h-index: 26
Publications: 87
Citations: 2,010

Selected Publications

Changes in gut, microbiome, and cognition after doxorubicin, cyclophosphamide, and paclitaxel chemotherapy treatment (2026)

Scientific Reports 2 citations DOI OpenAlex
Implications of cyclophosphamide, methotrexate, and 5-fluorouracil chemotherapy on hippocampal-dependent cognition and gut microbiome (2025)

Frontiers in Microbiomes 1 citation DOI OpenAlex
Manganese Superoxide Dismutase: Structure, Function, and Implications in Human Disease (2025)

Antioxidants 44 citations DOI OpenAlex
The adverse effects of chemotherapy on bone mass are not prevented by senolytics (2025)

Scientific Reports DOI OpenAlex
A Bibliometric Analysis of Research Examining How Space Radiation Affects Human and Rodent Cognition, 1990–2023 (2024)

Radiation DOI OpenAlex
MnSOD Mimetics in Therapy: Exploring Their Role in Combating Oxidative Stress-Related Diseases (2024)

Antioxidants 26 citations DOI OpenAlex
Summer undergraduate biomedical research program for underrepresented minority students in a rural, low-income state (2024)

Frontiers in Public Health 1 citation DOI OpenAlex
Physiological and cognitive changes after treatments of cyclophosphamide, methotrexate, and fluorouracil: implications of the gut microbiome and depressive-like behavior (2023)

Frontiers in Neuroscience 13 citations DOI OpenAlex
Sulforaphane’s Multifaceted Potential: From Neuroprotection to Anticancer Action (2023)

Molecules 56 citations DOI OpenAlex
Effects of Simulated 5-Ion Galactic Cosmic Radiation on Function and Structure of the Mouse Heart (2023)

Life 8 citations DOI OpenAlex
Abstract P3-08-08: Establishment of a Breast Cancer Rat Model of Chemotherapy-Induced Cardiotoxicity (2023)

Cancer Research DOI OpenAlex
Effect of Sirt3 on hippocampal MnSOD activity, mitochondrial function, physiology, and cognition in an aged murine model (2023)

Behavioural Brain Research 9 citations DOI OpenAlex
Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, And Cognition in an Aged Murine Model (2022)

SSRN Electronic Journal DOI OpenAlex
Effect of Sirt3 on Hippocampal MnSOD Activity, Mitochondrial Function, Physiology, and Cognition in an Aged Murine Model (2022)

SSRN Electronic Journal DOI OpenAlex
Chemotherapy induced oxidative stress in the ovary: drug-dependent mechanisms and potential interventions (2022)

Biology of Reproduction 24 citations DOI OpenAlex

View all publications on OpenAlex →

ARA Academy 2023 ARA Fellow

Dr. Allen is an Associate Professor and Graduate Program Director at the Division of Radiation Health, Department of Pharmaceutical Sciences at UAMS. He holds a PhD in Evolution, Ecology, and Behavior and served as a Captain in the US Army Infantry from 2004-2010. His work focuses on community science development and introducing research and discovery to underserved populations in Arkansas.

Policy Impact

Builds research capacity and STEM engagement in underserved Arkansas communities, expanding the state's scientific workforce pipeline and health research infrastructure.

Growth Areas

['Population Health Innovations & Clinical Research']

Resources

Discovery Economics Article Project Scope Video ARA Academy Profile

Federal Grants 2 $639,667 total

NIH Co-PI Feb 2024 - Apr 2025

Initiative for Maximizing Student Development(IMSD)

National Institute of General Medical Sciences $332,317 T32

NIH Contact PI Aug 2021 - Jul 2025

MnBuOE as a Novel Chemosensitizer for Breast Cancer and Neuroprotector

National Cancer Institute $307,350 R01

Grants & Funding

As listed on this researcher's institutional profile. Federal awards with verified records are shown above.

The Protein C Pathway in Mitigation of Radiation-Induced Endothelial and Vascular Dysfunction NIH
Center for Studies of Host Response to Cancer Therapy NIH
Carcinogenesis and Central Nervous System Risks for Space Radiation National Aeronautics & Space Administration via Loma Linda University Medical Center
Metabolomics Based Prediction of Delayed Effects of Acute Radiation Exposure NIH/Nat. Inst. of Allergy & Infectious Diseases via Nelson Scientific Labs, LLC
EPSCoR - CASE Summer National Science Foundation via Arkansas Economic Development Commission
ABI P. Prather NIH T32 FY26 Y3 State of Arkansas
RII Track-1: Arkansas ASSET Initiative III - Continuation Y5 - Continuation National Science Foundation via Arkansas Economic Development Commission
Photobiomodulation to Ameliorate Neuronal Degeneration and Cognitive Decline after Mixed Field Irradiation - Continuation National Aeronautics & Space Administration