Match tier
Confirmed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
X
Xuefei Cao
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
Also affiliated: University of Southern California (2007–2023); United States Food and Drug Administration (2011–2025); Tianjin University of Science and Technology (2013); Nanjing Tech University (2021–2023); Harbin Medical University (2017); California Southern University (2009); Beijing Forestry University (2024); Xi'an Honghui Hospital (2025); Heilongjiang Provincial Hospital (2022); First Affiliated Hospital of Harbin Medical University (2017); University of Cincinnati (2001–2003); South China University of Technology (2014)
Faculty Researcher
19 h-index
52 pubs
1,028 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Xuefei Cao's research focuses on evaluating the toxicity of various substances using in vitro human airway tissue models. This work investigates the potential for DNA damage and mutagenicity caused by inhaled chemicals, such as formaldehyde and glutaraldehyde fumes, and cigarette smoke. Cao employs advanced techniques like the CometChip assay and Duplex Sequencing to assess genotoxicity. Additional research explores the integration of transcriptome analysis with pathophysiological endpoints to understand chemical toxicity more comprehensively. Cao has published 52 papers, accumulating over 1,000 citations, and holds an h-index of 19. Collaborations include Robert H. Heflich, Qiangen Wu, Rebecca Wynne, and Roberta A. Mittelstaedt, all at the National Center for Toxicological Research.
Metrics
- h-index: 19
- Publications: 52
- Citations: 1,028
Selected Publications
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Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays (2026)
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Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model (2025)
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Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations (2024)
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Key Challenges and Recommendations for <i>In Vitro</i> Testing of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters (2023)
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Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose (2022)
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Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model (2022)
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Ciliary Beat Frequency: Proceedings and Recommendations from a Multi-laboratory Ring Trial Using 3-D Reconstituted Human Airway Epithelium to Model Mucociliary Clearance (2022)
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Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model (2022)
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Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity (2021)
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Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing (2021)
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Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model (2021)
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Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model (2021)
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Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model (2021)
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Detection of Pig-a Mutant Erythrocytes in the Peripheral Blood of Rats and Mice (2020)
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In vitro dosimetry analyses for acrolein exposure in normal human lung epithelial cells and human lung cancer cells (2020)
Collaboration Network
Top Collaborators
Levan Muskhelishvili
8 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
Showing 5 of 8 shared publications
Kelly J. Davis
7 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
Showing 5 of 7 shared publications
Robert H. Heflich
National Center for Toxicological Research
6 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Key Challenges and Recommendations for <i>In Vitro</i> Testing of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity
- Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model
Showing 5 of 6 shared publications
Qiangen Wu
National Center for Toxicological Research
5 shared publications
In database
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model
Rebecca Wynne
National Center for Toxicological Research
5 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays
Diego Rua
Office of Science (US)
4 shared publications
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model
Yiying Wang
National Center for Toxicological Research (US)
3 shared publications
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Matthew Bryant
United States Food and Drug Administration
3 shared publications
In database
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model
Roberta A. Mittelstaedt
National Center for Toxicological Research
3 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity
Baiping Ren
National Center for Toxicological Research
3 shared publications
In database
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model
Yuan Le
National Center for Toxicological Research
3 shared publications
In database
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model
- Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays
Priya Tripathi
National Center for Toxicological Research (US)
2 shared publications
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
Yue Wu
United States Food and Drug Administration (US)
2 shared publications
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model
Tao Chen
United States Food and Drug Administration (US)
2 shared publications
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model
Hans Rosenfeldt
United States Food and Drug Administration (US)
2 shared publications
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model
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