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Xuefei Cao Data-verified
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Researcher
faculty
19 h-index
52 pubs
1,005 cited
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Xuefei Cao investigates the toxicity of various substances, particularly focusing on their effects on human airway tissues using in vitro models. Her research has explored the genetic toxicity of chemicals, assessing DNA damage and mutagenesis, and has utilized quantitative in vitro to in vivo extrapolation methods to estimate safe exposure levels. Cao has also integrated transcriptome analysis with pathophysiological endpoints to evaluate the toxicity of cigarette smoke and specific chemicals like formaldehyde, glutaraldehyde, and ortho-phthalaldehyde in human airway epithelial tissue models. She has published 52 papers, accumulating 986 citations, and holds an h-index of 19. Cao has collaborated extensively with researchers at the National Center for Toxicological Research, including Robert H. Heflich and Qiangen Wu, with whom she shares five co-authored publications.
Metrics
- h-index: 19
- Publications: 52
- Citations: 1,005
Selected Publications
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Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays (2026)
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Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model (2025)
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Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations (2024)
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Key Challenges and Recommendations for <i>In Vitro</i> Testing of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters (2023)
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Quantitative in vitro to in vivo extrapolation of genotoxicity data provides protective estimates of in vivo dose (2022)
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Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model (2022)
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Ciliary Beat Frequency: Proceedings and Recommendations from a Multi-laboratory Ring Trial Using 3-D Reconstituted Human Airway Epithelium to Model Mucociliary Clearance (2022)
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Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model (2022)
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Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity (2021)
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Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing (2021)
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Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model (2021)
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Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model (2021)
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Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model (2021)
Collaboration Network
Top Collaborators
Levan Muskhelishvili
8 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
Showing 5 of 8 shared publications
Kelly J. Davis
7 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
Showing 5 of 7 shared publications
Qiangen Wu
National Center for Toxicological Research
5 shared publications
In database
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model
Robert H. Heflich
National Center for Toxicological Research
5 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Key Challenges and Recommendations for <i>In Vitro</i> Testing of Tobacco Products for Regulatory Applications: Consideration of Test Materials and Exposure Parameters
- Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model
Rebecca Wynne
United States Food and Drug Administration
4 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Diego Rua
Office of Science (US)
4 shared publications
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model
Carlos Clavijo
University of Southern California (US)
4 shared publications
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
H. Helen Lin
4 shared publications
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
Yuan Chen
City Of Hope National Medical Center (US)
4 shared publications
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
Hsiu‐Ming Shih
Institute of Biomedical Sciences, Academia Sinica (TW)
4 shared publications
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
David K. Ann
University of Southern California (US)
4 shared publications
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Supplementary Figure 1 from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
- Data from SUMOylation of HMGA2: selective destabilization of promyelocytic leukemia protein via proteasome
Yiying Wang
National Center for Toxicological Research (US)
3 shared publications
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Matthew Bryant
United States Food and Drug Administration
3 shared publications
In database
- Integration of transcriptome analysis with pathophysiological endpoints to evaluate cigarette smoke toxicity in an in vitro human airway tissue model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human <i>In Vitro</i> Airway Tissue Model
- Transcriptome analysis reveals lung-specific miRNAs associated with impaired mucociliary clearance induced by cigarette smoke in an in vitro human airway tissue model
Roberta A. Mittelstaedt
National Center for Toxicological Research
3 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing <scp>DNA</scp> damage with the <scp>CometChip</scp> and mutagenesis by Duplex Sequencing
- Effect of life stage and target tissue on dose–response assessment of ethyl methane sulfonate‐induced genotoxicity
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Baiping Ren
National Center for Toxicological Research
3 shared publications
In database
- Evaluating the Sub-Acute Toxicity of Formaldehyde Fumes in an In Vitro Human Airway Epithelial Tissue Model
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Characterizing the Pulmonary Toxicity and Potential Mutagenicity of Formaldehyde Fumes in a Human Bronchial Epithelial Tissue Model
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