Biofilms

Research in biofilms examines how communities of microorganisms adhere to surfaces and to each other, forming protective matrices. Investigations explore the genetic and molecular mechanisms that govern biofilm formation, maturation, and dispersal. Studies also focus on understanding the unique properties of biofilms, such as their increased resistance to antimicrobial agents and host immune responses, and the development of strategies to prevent or eradicate them. Techniques employed include microscopy, genomics, proteomics, and *in vitro* and *in vivo* models of infection.

This work holds significant relevance for Arkansas. Biofilm research directly impacts public health by addressing persistent infections, such as those associated with medical implants and chronic wounds, which can pose challenges in healthcare settings across the state. Furthermore, understanding biofilm formation is crucial for industries in Arkansas that deal with water quality, food safety, and agricultural processes, where unwanted microbial growth can lead to economic losses and public health concerns.

This research area benefits from strong interdisciplinary connections with fields including microbial infections and disease, bacterial genetics, host-pathogen interactions, and drug resistance mechanisms. Engagement across multiple institutions within Arkansas fosters a comprehensive approach to studying these complex microbial communities.