William Slikker
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Director
Also affiliated: Northwestern University (2016); Rush University Medical Center (2012–2020); Center for Food Safety and Applied Nutrition (2024); Boston Children's Hospital (2018); Environmental Protection Agency (2024); American Institute of Certified Public Accountants (2016); RELX Group (Netherlands) (2000); United States Food and Drug Administration (1982–2024); Center for Drug Evaluation and Research (2016); Harvard University (2018); Howard University (2024); University of British Columbia (1992); Medical University of South Carolina (2003); University of California, Santa Barbara (1976); University of California, Los Angeles (2004); University of Georgia (2024); University of Dundee (1983); University of Milan (2024); American Society for Surgery of the Hand (2016); Hospital for Sick Children (1997); University of Mississippi (1988); Office of the Director (2007–2021); Zimmer Biomet (United States) (2003); National Health Insurance Fund (2015); Children's Specialty Group (2016); Charles River Laboratories (United States) (2024); Stanford Medicine (2011); Office of the Director (2008–2022); Connecticut Department of Public Health (2003); Kaiser Permanente San Leandro Medical Center (2021–2022); Food and Drug Administration (2006–2024); National Research Council Canada (1986); Arkansas Department of Agriculture (2025); Zhejiang University (2012); University of California, Davis (1981–2017); Stanford University (2011–2012); Mississippi State University (2024)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
William Slikker directs research focused on regulatory science, with a particular emphasis on toxicology and the application of emerging technologies. His work has explored the regulatory landscape of nanotechnology and nanoplastics from a global perspective, and the impact of new technologies on regulatory science frameworks. He has also investigated the intersection of artificial intelligence, real-world data, and public health, specifically in the context of drug and food safety.
Slikker's research extends to neuroprotection and neurotoxicity. He has studied the neurochemical effects of long-term methylphenidate treatment in nonhuman primates using microPET/CT imaging. His laboratory has also focused on establishing neural stem cells from fetal monkey brains for neurotoxicity testing and has investigated the neuroprotective potential of carnitine. His work also includes the transition from traditional animal models to New Approach Methodologies (NAMs) to protect human and animal health.
With an h-index of 67 and over 480 publications, Slikker is recognized as a highly cited researcher. His key collaborators include Tucker A. Patterson, Leah E. Latham, John Talpos, and Weida Tong, all from the National Center for Toxicological Research. He maintains an active laboratory website to disseminate his research.
Metrics
- h-index: 67
- Publications: 463
- Citations: 19,831
Selected Publications
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Emerging therapeutics and safety: Transdisciplinary science to address unique safety challenges of cannabis and psychedelics (2026)
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Proposed key characteristics of neurotoxic chemicals (2025)
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Realizing Impact of Artificial Intelligence in Real World Enhances Public Health (2025)
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Biomarkers of Neurotoxicity and Disease (2025)
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Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods (2024)
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Integrating artificial intelligence with bioinformatics promotes public health (2023)
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In pursuit of precision medicine for brain injury and neurotoxicity and improved protection of human health (2023)
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Society for birth defects research and prevention's multidisciplinary research needs workshop 2022: A call to action (2023)
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Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing (2023)
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Artificial intelligence and real-world data for drug and food safety – A regulatory science perspective (2023)
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Discontinuation of methylphenidate after long-term exposure in nonhuman primates (2023)
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Application of Nonhuman Primate Models in the Studies of Pediatric Anesthesia Neurotoxicity (2022)
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Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits (2022)
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Analysis of biofluid lipid changes: potential biomarkers for detecting central nervous system diseases and neurotoxicity (2021)
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MicroPET/CT assessment of neurochemical effects in the brain after long-term methylphenidate treatment in nonhuman primates (2021)
Collaboration Network
Top Collaborators
- Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
- Biomarkers of Neurotoxicity and Disease
- Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits
- Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
- Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits
- Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
- Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits
- MicroPET/CT assessment of neurochemical effects in the brain after long-term methylphenidate treatment in nonhuman primates
- Discontinuation of methylphenidate after long-term exposure in nonhuman primates
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
- Neuroprotective Effects of Carnitine and Its Potential Application to Ameliorate Neurotoxicity
- Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits
- Regulatory landscape of nanotechnology and nanoplastics from a global perspective
- Artificial intelligence and real-world data for drug and food safety – A regulatory science perspective
- MicroPET/CT assessment of neurochemical effects in the brain after long-term methylphenidate treatment in nonhuman primates
- Discontinuation of methylphenidate after long-term exposure in nonhuman primates
- MicroPET/CT assessment of neurochemical effects in the brain after long-term methylphenidate treatment in nonhuman primates
- Discontinuation of methylphenidate after long-term exposure in nonhuman primates
- MicroPET/CT assessment of neurochemical effects in the brain after long-term methylphenidate treatment in nonhuman primates
- Discontinuation of methylphenidate after long-term exposure in nonhuman primates
- Establishment of neural stem cells from fetal monkey brain for neurotoxicity testing
- Phencyclidine (PCP)-induced neurotoxicity and behavioral deficits
- Protecting Human and Animal Health: The Road from Animal Models to New Approach Methods
- Society for birth defects research and prevention's multidisciplinary research needs workshop 2022: A call to action
- Biomarkers of Neurotoxicity and Disease
- In pursuit of precision medicine for brain injury and neurotoxicity and improved protection of human health
- Biomarkers of Neurotoxicity and Disease
- In pursuit of precision medicine for brain injury and neurotoxicity and improved protection of human health
- Integrating artificial intelligence with bioinformatics promotes public health
- Realizing Impact of Artificial Intelligence in Real World Enhances Public Health
- Regulatory landscape of nanotechnology and nanoplastics from a global perspective
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