Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
A
A. Edwards
Researcher
Also affiliated: Arkansas Children's Hospital (2024–2025); Arkansas Children's Nutrition Center (2025)
Faculty Researcher
3 h-index
16 pubs
130 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
A. Edwards' research investigates molecular mechanisms related to gene regulation and cellular processes. Recent publications focus on the interaction of G-quadruplex DNA with the DEAD-box helicase Ded1p, exploring how these structures influence helicase activity and phase separation. Additionally, work has explored therapeutic interventions for impaired alveolar development, specifically targeting CELA1 inhibition to improve septation in mouse models. Another area of investigation involves the development of novel murine models for tracheal occlusion to study altered respiratory dynamics. Edwards has co-authored 16 publications, with 127 total citations, and holds an h-index of 3. Key collaborators at the University of Arkansas for Medical Sciences include Brian M. Varisco, John C. Marecki, Kevin D. Raney, and Alicia K. Byrd.
Metrics
- h-index: 3
- Publications: 16
- Citations: 130
Selected Publications
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Novel murine partial tracheal occlusion model with altered respiratory dynamics (2025)
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Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development (2025)
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Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development (2024)
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G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p (2021)
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G-Quadruplex loops regulate PARP-1 enzymatic activation (2020)
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G‐Quadruplex Loop Length Regulates PARP‐1 Enzymatic Activation (2019)
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DEAD-box RNA helicases Dbp2, Ded1 and Mss116 bind to G-quadruplex nucleic acids and destabilize G-quadruplex RNA (2019)
Collaboration Network
Top Collaborators
Rashika Joshi
Cincinnati Children's Hospital Medical Center (US)
3 shared publications
- Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
- Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
- Novel murine partial tracheal occlusion model with altered respiratory dynamics
Brian M. Varisco
Arkansas Children's Hospital
3 shared publications
In database
- Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
- Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
- Novel murine partial tracheal occlusion model with altered respiratory dynamics
Noah J. Smith
University of Cincinnati Medical Center (US)
2 shared publications
- Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
- Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
Jerilyn K. Gray
Cincinnati Children's Hospital Medical Center (US)
2 shared publications
- Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
- Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
Elham Shahreki
Arkansas Children's Hospital
2 shared publications
In database
- Targeting CELA1 to Improve Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
- Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
Jun Gao
University of Arkansas for Medical Sciences
1 shared publication
In database
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
Zhaofeng Gao
RaNA Therapeutics (United States) (US)
1 shared publication
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
Andrea Putnam
Case Western Reserve University (US)
1 shared publication
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
Alicia K. Byrd
University of Arkansas for Medical Sciences
1 shared publication
In database
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
Sarah Venus
Indiana University School of Medicine
1 shared publication
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
John C. Marecki
University of Arkansas for Medical Sciences
1 shared publication
In database
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
H Löwe
University of Arkansas for Medical Sciences
1 shared publication
In database
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
Eckhard Jankowsky
Indiana University School of Medicine
1 shared publication
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
Kevin D. Raney
University of Arkansas for Medical Sciences
1 shared publication
In database
- G-quadruplex DNA inhibits unwinding activity but promotes liquid–liquid phase separation by the DEAD-box helicase Ded1p
Hitesh Desmukh
Perinatal Institute (GB)
1 shared publication
- Inhibition of CELA1 Improves Septation in the Mouse Hyperoxia Model of Impaired Alveolar Development
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