Match tier
Listed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-08-08
J
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
James C. Douglas investigates the neuroinflammatory and neurodevelopmental effects of ethanol exposure, particularly in the context of fetal alcohol spectrum disorders (FASD) and alcohol use disorder. His research utilizes mouse models to study how ethanol impacts brain regions such as the cerebellum and hippocampus. Douglas's work has explored ethanol's modulation of neuroinflammation, myelination, and gene expression in the developing brain. He has published on the signaling pathways involved in ethanol-induced neuroinflammation, including the roles of TLR4 and MyD88. Douglas's scholarship metrics include an h-index of 13 and 18 total publications. He has collaborated with several researchers at the University of Arkansas for Medical Sciences, including Paul D. Drew, Cynthia J.M. Kane, and Tonya Rafferty, with whom he shares multiple publications.
Metrics
- h-index: 13
- Publications: 18
- Citations: 731
Selected Publications
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Early Postnatal Ethanol Exposure Has Long-Term Behavioral Consequences in Female Mice (2026)
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Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum (2024)
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Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling (2023)
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Developmental ethanol exposure has minimal impact on cerebellar microglial dynamics, morphology, and interactions with Purkinje cells during adolescence (2023)
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Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset (2023)
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Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation (2022)
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Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders (2021)
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Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders (2021)
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Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period (2021)
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Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders (2021)
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PPAR-γ agonists suppress neuroinflammation in a FASD animal model (2017)
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Protection against alcohol-induced neuronal and cognitive damage by the PPARγ receptor agonist pioglitazone (2017)
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Pioglitazone Blocks Ethanol Induction of Microglial Activation and Immune Responses in the Hippocampus, Cerebellum, and Cerebral Cortex in a Mouse Model of Fetal Alcohol Spectrum Disorders (2015)
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Effects of ethanol on immune response in the brain: region-specific changes in aged mice (2013)
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Effects of Ethanol on Immune Response in the Brain: Region-Specific Changes in Adolescent Versus Adult Mice (2013)
Collaboration Network
Top Collaborators
Paul D. Drew
University of Arkansas for Medical Sciences
9 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
Showing 5 of 9 shared publications
Cynthia J.M. Kane
University of Arkansas for Medical Sciences
7 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
Showing 5 of 7 shared publications
Tonya Rafferty
University of Arkansas for Medical Sciences
6 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 6 shared publications
Victoria M. Niedzwiedz‐Massey
University of Arkansas for Medical Sciences
4 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Ania K. Majewska
University of Rochester (US)
4 shared publications
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset
- Developmental ethanol exposure has minimal impact on cerebellar microglial dynamics, morphology, and interactions with Purkinje cells during adolescence
- Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum
Kalee N. Holloway
University of Arkansas for Medical Sciences
4 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
- Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset
Jennifer W. Johnson
University of Arkansas for Medical Sciences
2 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
MaKenna Y. Cealie
University of Rochester (US)
2 shared publications
- Developmental ethanol exposure has minimal impact on cerebellar microglial dynamics, morphology, and interactions with Purkinje cells during adolescence
- Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum
Erik VonKaenel
Pacific Northwest National Laboratory (US)
2 shared publications
- Developmental ethanol exposure has minimal impact on cerebellar microglial dynamics, morphology, and interactions with Purkinje cells during adolescence
- Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum
Matthew N. McCall
University of Rochester (US)
2 shared publications
- Developmental ethanol exposure has minimal impact on cerebellar microglial dynamics, morphology, and interactions with Purkinje cells during adolescence
- Developmental Ethanol Exposure Impacts Purkinje Cells but Not Microglia in the Young Adult Cerebellum
Kevin D. Phelan
University of Arkansas for Medical Sciences
1 shared publication
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
Marisa R. Pinson
Texas A&M University (US)
1 shared publication
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
Rajesh C. Miranda
Texas A&M University (US)
1 shared publication
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
P.A.L. Wight
University of Arkansas for Medical Sciences
1 shared publication
In database
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
Michael D. Berquist
University of Arkansas for Medical Sciences
1 shared publication
In database
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
Similar Researchers
Based on overlapping research topics
Paul D. Drew
University of Arkansas for Medical Sciences
Fetal Alcohol Spectrum Disorders
Neuroinflammation and Neurodegeneration Mechanisms
Disease Models, Animal
Jennifer W. Johnson
University of Arkansas for Medical Sciences
Neuroinflammation and Neurodegeneration Mechanisms
Disease Models, Animal
Substance Abuse Treatment and Outcomes
Victoria M. Niedzwiedz‐Massey
University of Arkansas for Medical Sciences
Fetal Alcohol Spectrum Disorders
Neuroinflammation and Neurodegeneration Mechanisms
Neuroscience and Neuropharmacology Research
Tonya Rafferty
University of Arkansas for Medical Sciences
Neuroinflammation and Neurodegeneration Mechanisms
Disease Models, Animal
Substance Abuse Treatment and Outcomes
Akshay Padala
University of Arkansas for Medical Sciences
Disease Models, Animal
Neuroscience and Neuropharmacology Research
Genomics and Chromatin Dynamics
Heidi D. Hughes-Meredith
University of Arkansas for Medical Sciences
Disease Models, Animal
Substance Abuse Treatment and Outcomes
Neuroscience and Neuropharmacology Research