Cynthia J.M. Kane

High Impact

Researcher

UAMS

Last publication 2023 Last refreshed 2026-05-16

faculty

26 h-index 56 pubs 2,416 cited

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OverviewAI-generated summary

Cynthia J.M. Kane's research focuses on the neurobiological effects of ethanol exposure, particularly in the context of fetal alcohol spectrum disorders (FASD) and alcohol use disorder (AUD). Her work utilizes mouse models to investigate how ethanol influences neuroinflammation, myelination, and gene expression in critical brain regions like the cerebellum and hippocampus.

Recent publications from Kane's group detail ethanol's impact on the developing brain, examining pathways such as TLR4 and MyD88-dependent signaling in inducing neuroinflammation. Her studies also explore the temporal dynamics of these effects, focusing on disease onset and the specific transcriptomic changes that occur following developmental ethanol exposure. She has collaborated with researchers at the University of Arkansas for Medical Sciences, including Paul D. Drew, James C. Douglas, Tonya Rafferty, and Kalee N. Holloway, on multiple shared publications.

Kane is recognized as a highly cited researcher, with a h-index of 25 and over 2,400 citations across 56 publications. She leads a research group that investigates the complex mechanisms underlying alcohol's detrimental effects on brain development and function.

Metrics

h-index: 26
Publications: 56
Citations: 2,416

Selected Publications

Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling (2023)

25 citations DOI OpenAlex
Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset (2023)

12 citations DOI OpenAlex
Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression (2023)

10 citations DOI OpenAlex
Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation (2022)

16 citations DOI OpenAlex
Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders (2021)

13 citations DOI OpenAlex
Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders (2021)

15 citations DOI OpenAlex
Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period (2021)

13 citations DOI OpenAlex
Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders (2021)

24 citations DOI OpenAlex