Biography and Research Information
OverviewAI-generated summary
Tonya Rafferty's research investigates the effects of ethanol on neuroinflammation and myelination, particularly in the cerebellum and hippocampus. Her work utilizes mouse models to examine alcohol use disorder and fetal alcohol spectrum disorders, exploring the molecular mechanisms involved, such as TLR4 and MyD88 signaling pathways. Rafferty has also studied the role of P2X7-mediated T cell activation in salt-sensitive hypertension. Her scholarship includes 29 publications, with an h-index of 10 and over 500 citations. She has collaborated extensively with researchers at the University of Arkansas for Medical Sciences, including Katherine Deck and Christoph Mora, with whom she shares 14 publications.
Metrics
- h-index: 10
- Publications: 30
- Citations: 518
Selected Publications
-
IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287 (2025)
-
Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288 (2025)
-
Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension (2025)
-
Uncovering immune pathways for therapeutic targeting of hypertension (2025)
-
Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025)
-
Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction (2025)
-
Establishment of resident memory T cells anchors hypertension in the kidney (2025)
-
T Cells Drive Kidney Memory for Hypertension (2024)
-
Abstract P200: Immune memory contributes to chronic hypertension recurrence (2024)
-
P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION (2024)
-
O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION (2024)
-
Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling (2023)
-
Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset (2023)
-
Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression (2023)
-
Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation (2022)
Collaboration Network
Top Collaborators
Katherine Deck
University of Arkansas for Medical Sciences
14 shared publications
In database
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- T Cells Drive Kidney Memory for Hypertension
- 2137-LB: ATP-P2X7 Mediated T-Cell Activation in Obesity-Induced Type 2 Diabetes
Showing 5 of 14 shared publications
Christoph Mora
University of Arkansas for Medical Sciences
14 shared publications
In database
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- T Cells Drive Kidney Memory for Hypertension
- 2137-LB: ATP-P2X7 Mediated T-Cell Activation in Obesity-Induced Type 2 Diabetes
Showing 5 of 14 shared publications
Shengyu Mu
University of Arkansas for Medical Sciences
14 shared publications
In database
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- T Cells Drive Kidney Memory for Hypertension
- 2137-LB: ATP-P2X7 Mediated T-Cell Activation in Obesity-Induced Type 2 Diabetes
Showing 5 of 14 shared publications
Shuoqiu Deng
University of Arkansas for Medical Sciences
9 shared publications
In database
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
Showing 5 of 9 shared publications
Yunmeng Liu
University of Arkansas for Medical Sciences
8 shared publications
In database
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- 2137-LB: ATP-P2X7 Mediated T-Cell Activation in Obesity-Induced Type 2 Diabetes
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
Showing 5 of 8 shared publications
Cynthia J.M. Kane
University of Arkansas for Medical Sciences
7 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 7 shared publications
Paul D. Drew
University of Arkansas for Medical Sciences
7 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 7 shared publications
James C. Douglas
University of Arkansas for Medical Sciences
6 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 6 shared publications
Yunmeng Liu
6 shared publications
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- T Cells Drive Kidney Memory for Hypertension
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
- Energy Overload: ATP-P2X7-Mediated T Cell Activation in Obesity-Induced Type 2 Diabetes 9286
Showing 5 of 6 shared publications
Pamela Rogers
University of Arkansas for Medical Sciences (US)
5 shared publications
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
- Energy Overload: ATP-P2X7-Mediated T Cell Activation in Obesity-Induced Type 2 Diabetes 9286
- Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288
- IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287
Victoria M. Niedzwiedz‐Massey
University of Arkansas for Medical Sciences
4 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Kalee N. Holloway
University of Arkansas for Medical Sciences
4 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression
- Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset
Lance Benson
University of Arkansas for Medical Sciences (US)
4 shared publications
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- Establishment of resident memory T cells anchors hypertension in the kidney
Pamela I. Rogers
University of Arkansas for Medical Sciences
4 shared publications
In database
- Establishment of resident memory T cells anchors hypertension in the kidney
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289
Yunping Guo
University of Arkansas for Medical Sciences
3 shared publications
In database
- <i>P2X7</i> -Mediated Antigen-Independent Activation of CD8 <sup>+</sup> T Cells Promotes Salt-Sensitive Hypertension
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
Similar Researchers
Based on overlapping research topics
Jennifer W. Johnson
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Immune Response and Inflammation
Birth, Development, and Health
Paul Drew
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Immune Response and Inflammation
Birth, Development, and Health
Mohamed A. Sadek
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Immune Response and Inflammation
Cardiovascular Function and Risk Factors
Mustafa N. Mithaiwala
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Immune Response and Inflammation
Substance Abuse Treatment and Outcomes
Kalee N. Holloway
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Immune Response and Inflammation
Substance Abuse Treatment and Outcomes
Hui‐Ming Chang
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Immune Response and Inflammation
Cardiovascular Function and Risk Factors