Tonya Rafferty

Researcher

University of Arkansas for Medical Sciences

faculty

10 h-index 29 pubs 504 cited

Research Areas

Neuroscience and Neuropharmacology Research Immune Response and Inflammation Pharmacological Effects and Toxicity Studies Birth, Development, and Health Cardiovascular Function and Risk Factors Substance Abuse Treatment and Outcomes Mental Health Research Topics

Is this your profile? Verify and claim your profile

OverviewAI-generated summary

Tonya Rafferty studies the effects of ethanol on neuroinflammation, myelination, and neurodevelopment, particularly in the context of fetal alcohol spectrum disorders (FASD) and alcohol use disorder (AUD). Her research has investigated how ethanol exposure impacts the cerebellum and hippocampus in mouse models. Rafferty's work has explored the molecular signaling pathways involved, including TLR4 and MyD88-dependent signaling, in response to chronic and binge ethanol administration.

Her publications also extend to other areas, including the role of P2X7-mediated T cell activation in hypertension. Rafferty has a scholarly output reflected in an h-index of 10 and over 500 citations across 29 publications. She has established a network of key collaborators at the University of Arkansas for Medical Sciences, including Katherine Deck, Christoph Mora, Shengyu Mu, and Pamela I. Rogers, with whom she has co-authored multiple publications.

Metrics

h-index: 10
Publications: 29
Citations: 504

Selected Publications

IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287 (2025) DOI
Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288 (2025) DOI
Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension (2025) DOI
Uncovering immune pathways for therapeutic targeting of hypertension (2025) DOI
Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025) DOI
Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction (2025) DOI
Establishment of resident memory T cells anchors hypertension in the kidney (2025) DOI
T Cells Drive Kidney Memory for Hypertension (2024) DOI
Abstract P200: Immune memory contributes to chronic hypertension recurrence (2024) DOI
P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION (2024) DOI
Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling (2023) DOI
Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset (2023) DOI
Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression (2023) DOI
Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation (2022) DOI
Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders (2021) DOI