Tonya Rafferty
Researcher
Also affiliated: Maine Farmland Trust (2024); University of Applied Management Studies (2025); Arkansas Department of Agriculture (2025)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Tonya Rafferty's research investigates the effects of ethanol on neuroinflammation, myelination, and neurodevelopment in mouse models. Her work has explored these impacts in the context of chronic plus binge alcohol use disorder and fetal alcohol spectrum disorders, examining changes in the cerebellum and hippocampus. Rafferty's publications detail the role of signaling pathways such as TLR4 and MyD88 in ethanol-induced neuroinflammation. Additionally, her research extends to the mechanisms underlying salt-sensitive hypertension, specifically investigating the role of CD8+ T cells and P2X7 receptor activation.
Rafferty has published 30 papers, accumulating 522 citations, and holds an h-index of 10. She has collaborated with several researchers at the University of Arkansas for Medical Sciences, including Katherine Deck and Christoph Mora, with whom she shares 14 co-authored publications.
Metrics
- h-index: 10
- Publications: 30
- Citations: 526
Selected Publications
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Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031 (2026)
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Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853 (2026)
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Kidney Resident Memory CD8+ T cells drive the immortality of hypertension (2026)
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Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension (2026)
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IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287 (2025)
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P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289 (2025)
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Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288 (2025)
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Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension (2025)
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Uncovering immune pathways for therapeutic targeting of hypertension (2025)
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Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025)
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Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction (2025)
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Establishment of resident memory T cells anchors hypertension in the kidney (2025)
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T Cells Drive Kidney Memory for Hypertension (2024)
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Abstract P200: Immune memory contributes to chronic hypertension recurrence (2024)
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P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION (2024)
Collaboration Network
Top Collaborators
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- T Cells Drive Kidney Memory for Hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
Showing 5 of 11 shared publications
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- T Cells Drive Kidney Memory for Hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
Showing 5 of 11 shared publications
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- T Cells Drive Kidney Memory for Hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
Showing 5 of 11 shared publications
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 7 shared publications
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 7 shared publications
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
Showing 5 of 7 shared publications
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
Showing 5 of 7 shared publications
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 6 shared publications
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset
- Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- Establishment of resident memory T cells anchors hypertension in the kidney
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- T Cells Drive Kidney Memory for Hypertension
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
- Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288
- IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287
- O14 KIDNEY RESIDENT MEMORY T CELLS MEDIATE THE CHRONIC PROGRESSION OF HYPERTENSION
- P227 MACROPHAGE TO MYOFIBROBLAST TRANSITION IN THE DEVELOPMENT OF DIASTOLIC DYSFUNCTION
- Abstract P200: Immune memory contributes to chronic hypertension recurrence
- Establishment of resident memory T cells anchors hypertension in the kidney
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
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