Ryan M. Allen
Assistant Professor
Also affiliated: University of Iowa (2025); MACOM (United States) (2014); Loughborough University (1969); Saint Louis University (2012–2019); Vanderbilt University (2014–2022); University of Missouri–St. Louis (2012); UCLouvain Saint-Louis Brussels (2012); University of North Carolina Hospitals (2025); Allen Institute (2016); Saint Louis University (2010–2019); Vanderbilt University Medical Center (2014–2025)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Ryan M. Allen's research focuses on the molecular mechanisms underlying disease, with a particular emphasis on the role of small RNAs, such as microRNAs (miRNAs) and small interfering RNAs (siRNAs), in various pathological processes. His work investigates how these molecules interact with cellular components and influence disease progression, including atherosclerosis and cancer.
Allen's publications detail his investigations into the biogenesis and function of extracellular vesicles, the structural optimization of therapeutic RNA conjugates for targeted delivery, and the impact of specific miRNAs on cardiovascular health in patient populations. He has explored the role of lipid transport in disease, examining how lipoproteins can deliver microbial small RNAs to macrophages, thereby driving inflammatory responses and contributing to atherosclerosis. Furthermore, his research extends to the modification of RNA molecules, such as m6A consensus sequences, and their effect on cellular and extracellular miRNA levels.
His scholarship metrics include an h-index of 20, with over 2,249 citations across 58 publications. Allen collaborates with researchers at the University of Arkansas for Medical Sciences, including Neha S. Dole, Amy Y. Sato, Umesh D. Wankhade, and Madeline Carroll, with whom he has co-authored multiple publications. He leads an active research group and maintains a lab website.
Metrics
- h-index: 20
- Publications: 58
- Citations: 2,273
Selected Publications
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Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression (2026)
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Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation (2025)
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Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation (2025)
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LDL delivery of microbial small RNAs drives atherosclerosis through macrophage TLR8 (2022)
Federal Grants 1 $401,971 total
Canonical and alternative functions of low-density lipoprotein in multiple myeloma
Grants & Funding
As listed on this researcher's institutional profile. Federal awards with verified records are shown above.
- DEAP Awards - R.Allen - UAMS VCRI - FY26 UAMS Division of Research and Innovation
Collaboration Network
Top Collaborators
- Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation
- Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression
- Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation
- Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression
- Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation
- Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression
- Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation
- Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression
- Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation
- Osteocytic Lipocalin-2 regulates bone formation locally through iron-dependent ferroptosis and Wnt suppression
- Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation
- Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation
- Lipocalin-2 Regulates Osteocyte Ferroptosis and Osteocyte-Osteoblast Crosstalk via Wnt Signaling to Control Bone Formation
- Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation
- Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation
- Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation
- Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation
- Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation
- Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation
- Plasminogen as a Ribonucleoprotein: Regulatory small RNA Cargo Modulates Fibrinolysis and Inflammation
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