Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
Biography and Research Information
OverviewAI-generated summary
Henry A. Palfrey conducts research focused on the role of eicosanoids in kidney and cardiovascular function, particularly in the context of radiation-induced kidney injury and potential therapeutic interventions. His work also involves developing novel medical devices and preparing them for market launch. Palfrey has investigated the effects of DPP-4 inhibitors on liver changes in rats, finding that sitagliptin can enhance adverse cardiac events in hypercholesterolemia models. He has also studied dual inhibitors of TGFβR1/MAP4K4, demonstrating their potential to reduce renal fibrosis and injury in mouse models. His research has been supported by collaborations with researchers from the University of Arkansas for Medical Sciences and the University of Arkansas at Fayetteville, including John D. Imig and Samaneh Goorani.
Metrics
- h-index: 3
- Publications: 10
- Citations: 415
Selected Publications
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Sorafenib Treatment Results in Greater Kidney Injury in Renal Hypoplasia Mice (Abstract ID: 272359) (2026)
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Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice (2025)
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591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice (2025)
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Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4 (2024)
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557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis. (2024)
Collaboration Network
Top Collaborators
Samaneh Goorani
University of Arkansas for Medical Sciences
4 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
John D. Imig
4 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Baku Acharya
University of Arkansas for Medical Sciences
3 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Brendan Frett
University of Arkansas for Medical Sciences
3 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Amod Sharma
University of Arkansas for Medical Sciences
2 shared publications
In database
- 557 Dual TGFβR1/MAP4K4 inhibitor reduces kidney injury in a mouse model of renal fibrosis.
- Attenuation of renal injury by administration of TK-850, a dual inhibitor of TGFβR1/MAP4K4
Abhishek Mishra
University of Arkansas for Medical Sciences
2 shared publications
In database
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Abdul H. Khan
University of Arkansas for Medical Sciences
2 shared publications
In database
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
- Transforming growth factor β receptor 1 and mitogen-activated protein 4 kinase 4 dual inhibitor, TK-850, reduces renal fibrosis in unilateral ureteral–obstructed mice
Mohani Abdul
University of Arkansas for Medical Sciences
1 shared publication
In database
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
Rupak Pathak
University of Arkansas for Medical Sciences
1 shared publication
In database
- 591 Low kidney mass contributes to enhanced fractionated irradiation-induced renal hemodynamic dysfunction in mice
Similar Researchers
Based on overlapping research topics
Abdul H. Khan
University of Arkansas for Medical Sciences
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Jing Liu
University of Arkansas for Medical Sciences
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