Match tier
Likely match
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
S
Svitlana Shpyleva
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Researcher
Also affiliated: Arkansas Children's Hospital (2013–2017); United States Food and Drug Administration (2013–2024); Biochemical Society (2025); R.E. Kavetsky Institute of Experimental Pathology, Oncology and Radiobiology (2009–2012)
Faculty Researcher
16 h-index
33 pubs
1,440 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Svitlana Shpyleva's research focuses on the application of computational methods to accelerate scientific literature review and drug safety assessment. Her work includes developing benchmark datasets for text mining and sentiment analysis to streamline regulatory literature review processes. Additionally, she has investigated the performance of large language models in screening scientific literature for pharmacovigilance data. Shpyleva also conducts research on the pharmacokinetics of specific compounds, such as cannabidiol and its metabolites, in animal models. Her scholarly output includes 33 publications with 1,424 citations, and her h-index is 15. She has collaborated with researchers at the National Center for Toxicological Research, including Leihong Wu and Joshua Xu, on multiple publications.
Metrics
- h-index: 16
- Publications: 33
- Citations: 1,440
Selected Publications
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Pharmacokinetics of cannabidiol and its metabolites in rhesus monkeys and New Zealand White rabbits (2025)
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Assessing the performance of large language models in literature screening for pharmacovigilance: a comparative study (2024)
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Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review (2022)
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Effect of methapyrilene hydrochloride on hepatic intracellular iron metabolism in vivo and in vitro (2017)
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Chemo brain or tumor brain - that is the question: the presence of extracranial tumors profoundly affects molecular processes in the prefrontal cortex of TumorGraft mice (2017)
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Overexpression of LINE-1 Retrotransposons in Autism Brain (2017)
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Organ-specific epigenetic changes induced by the non-genotoxic liver carcinogen methapyrilene in Fischer 344 rats (2016)
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Suppressing activity of tributyrin on hepatocarcinogenesis is associated with inhibiting the p53-CRM1 interaction and changing the cellular compartmentalization of p53 protein (2016)
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Sex-specific effects of cytotoxic chemotherapy agents cyclophospha-mide and mitomycin C on gene expression, oxidative DNA damage, and epigenetic alterations in the prefrontal cortex and hippocampus – an aging connection (2016)
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Abstract 920: Mechanism of the transferrin receptor 1 dysregulation in hepatocarcinogenesis (2015)
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MicroRNA-152-mediated dysregulation of hepatic transferrin receptor 1 in liver carcinogenesis (2015)
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Differentially expressed MicroRNAs provide mechanistic insight into fibrosis-associated liver carcinogenesis in mice (2015)
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Elevated 5-hydroxymethylcytosine in the Engrailed-2 (EN-2) promoter is associated with increased gene expression and decreased MeCP2 binding in autism cerebellum (2014)
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Interstrain differences in the progression of nonalcoholic steatohepatitis to fibrosis in mice are associated with altered hepatic iron metabolism (2014)
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Cerebellar Oxidative DNA Damage and Altered DNA Methylation in the BTBR T+tf/J Mouse Model of Autism and Similarities with Human Post Mortem Cerebellum (2014)
Collaboration Network
Top Collaborators
Leihong Wu
National Center for Toxicological Research
2 shared publications
In database
- Assessing the performance of large language models in literature screening for pharmacovigilance: a comparative study
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Joshua Xu
National Center for Toxicological Research
2 shared publications
In database
- Assessing the performance of large language models in literature screening for pharmacovigilance: a comparative study
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Si Chen
United States Food and Drug Administration
1 shared publication
In database
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Lei Guo
United States Food and Drug Administration (US)
1 shared publication
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Kelly C. Harris
United States Food and Drug Administration (US)
1 shared publication
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Tariq Fahmi
National Center for Toxicological Research
1 shared publication
In database
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Timothy Flanigan
National Center for Toxicological Research (US)
1 shared publication
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Weida Tong
National Center for Toxicological Research
1 shared publication
In database
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Zhen Ren
National Center for Toxicological Research (US)
1 shared publication
- Development of benchmark datasets for text mining and sentiment analysis to accelerate regulatory literature review
Dan Li
National Center for Toxicological Research (US)
1 shared publication
- Assessing the performance of large language models in literature screening for pharmacovigilance: a comparative study
Mingfeng Zhang
United States Food and Drug Administration (US)
1 shared publication
- Assessing the performance of large language models in literature screening for pharmacovigilance: a comparative study
Ying-Chi Lin
Kaohsiung Medical University (TW)
1 shared publication
- Assessing the performance of large language models in literature screening for pharmacovigilance: a comparative study
Ho-Yin Huang
Kaohsiung Medical University (TW)
1 shared publication
- Assessing the performance of large language models in literature screening for pharmacovigilance: a comparative study
Ting Li
National Center for Toxicological Research (US)
1 shared publication
- Assessing the performance of large language models in literature screening for pharmacovigilance: a comparative study
Qiangen Wu
Biochemical Society
1 shared publication
In database
- Pharmacokinetics of cannabidiol and its metabolites in rhesus monkeys and New Zealand White rabbits
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