Alicja Joanna Urbaniak
Instructor
Also affiliated: University of Arkansas Medical Center (2021); Adam Mickiewicz University in Poznań (2012–2017)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Alicja Joanna Urbaniak's research investigates the biological activity of modified compounds, with a focus on their potential as anticancer agents. Her work includes the synthesis and in vitro evaluation of new amides derived from colchicine, specifically targeting cancer cells. Urbaniak also studies the antitumor properties of natural compounds and their derivatives, such as salinomycin analogs and components found in Trametes versicolor (Turkey tail mushroom), demonstrating anti-melanoma activity. Her research explores both synthetic modifications of known bioactive molecules and the assessment of natural products for therapeutic applications. She has published 62 papers, accumulating 617 citations, and holds an h-index of 15. Key collaborators at the University of Arkansas for Medical Sciences include Angus M. MacNicol, Steven R. Post, Billie Heflin, and Timothy C. Chambers.
Metrics
- h-index: 15
- Publications: 61
- Citations: 613
Positions
-
Instructor 2020–presentUniversity of Arkansas for Medical Sciences Biochemistry and Molecular Biology ORCID
-
Post Doctoral Fellow 2017–2020University of Arkansas for Medical Sciences Biochemistry and Molecular Biology ORCID
-
Research Technician 2016–2017University of Arkansas for Medical Sciences Biochemistry and Molecular Biology ORCID
Selected Publications
-
Repurposing Monensin and Its Derivatives as Immune-Modulatory Candidates for Metastatic Breast Cancer (Abstract ID: 231537) (2026)
-
Pancreatic tumor microenvironment reprogramming via alloantigen-expressing virotherapy elicits tumor rejection and improves immunotherapy response (2026)
-
Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models (2025)
-
Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models (2025)
-
Monensin and Its Analogs Exhibit Activity Against Breast Cancer Stem-Like Cells in an Organoid Model (2025)
-
Abstract 947: Engineering a synthetic oncolytic virus to overcome apoptotic resistance and induce immunogenic cell death in pancreatic ductal adenocarcinoma (2025)
-
Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059) (2025)
-
474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells (2025)
-
Enhancing Neoadjuvant Virotherapy’s Effectiveness by Targeting Stroma to Improve Resectability in Pancreatic Cancer (2024)
-
Monensin and its derivatives increase MHC Class I and II presentations in breast cancer (2024)
-
383 Beyond Antibiotics: Monensin and its Derivatives as Promising Anti-Breast Cancer Agents (2024)
-
Synthesis and Anti‐Melanoma Activity of Acryloyl Pyridinone Analogues (2023)
-
Experimental pharmacology in precision medicine (2023)
-
Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle (2023)
-
Monensin and its Derivatives Exhibit Anti-Melanoma Activity In Vitro (2023)
Collaboration Network
Top Collaborators
- Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo
- Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents
- Salinomycin derivatives exhibit activity against primary acute lymphoblastic leukemia (ALL) cells in vitro
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes
Showing 5 of 26 shared publications
- Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo
- Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents
- Salinomycin derivatives exhibit activity against primary acute lymphoblastic leukemia (ALL) cells in vitro
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes
Showing 5 of 25 shared publications
- Synthesis, biological evaluation and molecular docking studies of new amides of 4-chlorothiocolchicine as anticancer agents
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Carbamate derivatives of colchicine show potent activity towards primary acute lymphoblastic leukemia and primary breast cancer cells—in vitro and ex vivo study
- Synthesis, biological evaluation and molecular docking studies of new amides of 4-bromothiocolchicine as anticancer agents
- Synthesis, anticancer activity and molecular docking studies of N-deacetylthiocolchicine and 4-iodo-N-deacetylthiocolchicine derivatives
Showing 5 of 15 shared publications
- The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle
- Synthesis and Anti‐Melanoma Activity of Acryloyl Pyridinone Analogues
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
Showing 5 of 12 shared publications
- Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo
- Salinomycin derivatives exhibit activity against primary acute lymphoblastic leukemia (ALL) cells in vitro
- Synthesis, antiproliferative activity and molecular docking of thiocolchicine urethanes
- Contrasting effects of microtubule destabilizers versus stabilizers on induction of death in G1 phase of the cell cycle
- The response of phyllodes tumor of the breast to anticancer therapy: An in vitro and ex�vivo study
Showing 5 of 11 shared publications
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- Monensin and its analogues show anti‐glioblastoma activity in an organoid model of cancer
- Monensin and its Derivatives Exhibit Anti-Melanoma Activity In Vitro
- 383 Beyond Antibiotics: Monensin and its Derivatives as Promising Anti-Breast Cancer Agents
Showing 5 of 10 shared publications
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- Monensin and its analogues show anti‐glioblastoma activity in an organoid model of cancer
- Monensin and its Derivatives Exhibit Anti-Melanoma Activity In Vitro
- 383 Beyond Antibiotics: Monensin and its Derivatives as Promising Anti-Breast Cancer Agents
Showing 5 of 10 shared publications
- Enhancing Neoadjuvant Virotherapy’s Effectiveness by Targeting Stroma to Improve Resectability in Pancreatic Cancer
- Multimodal reprogramming of the tumor microenvironment by MMR and dual checkpoint blockade in hepatocellular carcinoma models
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- 474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells
- Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059)
Showing 5 of 9 shared publications
- Biological activity of doubly modified salinomycin analogs – Evaluation in vitro and ex vivo
- Salinomycin derivatives exhibit activity against primary acute lymphoblastic leukemia (ALL) cells in vitro
- Synthesis and Anticancer Activity of Tertiary Amides of Salinomycin and Their C20‐oxo Analogues
- Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models
- Double Modification of Polyether Ionophores: Synthesis and Biological Activity of Novel Salinomycin Derivatives
Showing 5 of 8 shared publications
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models
- Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- Novel Salinomycin Analogs Show Improved Selectivity Towards Breast Cancer Stem Cells
Showing 5 of 8 shared publications
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models
- Musashi Exerts Control of Gonadotrope Target mRNA Translation During the Mouse Estrous Cycle
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- Novel Salinomycin Analogs Show Improved Selectivity Towards Breast Cancer Stem Cells
Showing 5 of 8 shared publications
- The mycelium of the Trametes versicolor synn. Coriolus versicolor (Turkey tail mushroom) exhibit anti-melanoma activity in vitro
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Primary acute lymphoblastic leukemia cells are susceptible to microtubule depolymerization in G1 and M phases through distinct cell death pathways
- Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle
- Synthesis and Anti‐Melanoma Activity of Acryloyl Pyridinone Analogues
Showing 5 of 8 shared publications
- Enhancing Neoadjuvant Virotherapy’s Effectiveness by Targeting Stroma to Improve Resectability in Pancreatic Cancer
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- 383 Beyond Antibiotics: Monensin and its Derivatives as Promising Anti-Breast Cancer Agents
- Monensin and its derivatives increase MHC Class I and II presentations in breast cancer
- 474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells
Showing 5 of 8 shared publications
- Anti-glioblastoma activity of monensin and its analogs in an organoid model of cancer
- Single and double modified salinomycin analogs target stem-like cells in 2D and 3D breast cancer models
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- Novel Salinomycin Analogs Show Improved Selectivity Towards Breast Cancer Stem Cells
- Abstract PS18-46: Inhibition of breast cancer stem cells in 2- and 3-dimensional culture by novel salinomycin analogs
Showing 5 of 7 shared publications
- Enhancing Neoadjuvant Virotherapy’s Effectiveness by Targeting Stroma to Improve Resectability in Pancreatic Cancer
- Evaluation of the Activity of Monensin and Its Analogs for Modulation of Stem-like Cell Functionality in 2D and 3D Breast Cancer Models
- Monensin and its derivatives increase MHC Class I and II presentations in breast cancer
- 474 Repositioning monensin: Enhancing anti-cancer activity and immune modulation in breast cancer cells
- Monensin and Its Analogs Offer a Multi-Targeted Approach to Enhancing Metastatic Breast Cancer Immunogenicity and Cell Death (Abstract ID: 163059)
Showing 5 of 7 shared publications
Similar Researchers
Based on overlapping research topics