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Biography and Research Information
OverviewAI-generated summary
Sorena Lo's research investigates the impact of cold storage and transplantation on kidney function, with a particular focus on proteasome function and mitochondrial protein homeostasis. Lo has published work examining how renal cold storage prior to transplantation impairs proteasome function and mitochondrial proteostasis, potentially leading to exacerbated renal damage. Further research has explored methods to mitigate these effects, including targeting mitochondria during cold storage and investigating the role of specific molecules like the BK activator NS11021 in protecting kidneys from cold storage-induced injury. Lo's work also addresses the immune response, noting the aberrant activation of the complement system and the induction of interferon-gamma and STAT-1 in kidney grafts following cold storage and transplantation. Collaborations include Nirmala Parajuli, Dinesh Bhattarai, Neriman Gökden, and Seongok Lee, all at the University of Arkansas for Medical Sciences, with whom Lo has co-authored multiple publications.
Metrics
- h-index: 6
- Publications: 8
- Citations: 77
Selected Publications
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Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function (2024)
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Cold Storage Followed by Transplantation Induces Interferon-Gamma and STAT-1 in Kidney Grafts (2023)
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Aberrant activation of the complement system in renal grafts is mediated by cold storage (2021)
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The BK activator NS11021 partially protects rat kidneys from cold storage and transplantation-induced mitochondrial and renal injury (2020)
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Targeting Mitochondria during Cold Storage to Maintain Proteasome Function and Improve Renal Outcome after Transplantation (2020)
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Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage (2019)
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Renal cold storage followed by transplantation impairs proteasome function and mitochondrial protein homeostasis (2018)
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Albumin Level in Transplanted Kidneys is Higher inThose That Underwent Cold Storage BeforeTransplantation (2018)
Collaboration Network
Top Collaborators
- Renal cold storage followed by transplantation impairs proteasome function and mitochondrial protein homeostasis
- Targeting Mitochondria during Cold Storage to Maintain Proteasome Function and Improve Renal Outcome after Transplantation
- Aberrant activation of the complement system in renal grafts is mediated by cold storage
- Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage
- The BK activator NS11021 partially protects rat kidneys from cold storage and transplantation-induced mitochondrial and renal injury
Showing 5 of 8 shared publications
- Renal cold storage followed by transplantation impairs proteasome function and mitochondrial protein homeostasis
- The BK activator NS11021 partially protects rat kidneys from cold storage and transplantation-induced mitochondrial and renal injury
- Aberrant activation of the complement system in renal grafts is mediated by cold storage
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Albumin Level in Transplanted Kidneys is Higher inThose That Underwent Cold Storage BeforeTransplantation
- Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage
- Cold Storage Increases Albumin and Advanced Glycation-End Product-Albumin Levels in Kidney Transplants: A Possible Cause for Exacerbated Renal Damage
- Targeting Mitochondria during Cold Storage to Maintain Proteasome Function and Improve Renal Outcome after Transplantation
- The BK activator NS11021 partially protects rat kidneys from cold storage and transplantation-induced mitochondrial and renal injury
- The BK activator NS11021 partially protects rat kidneys from cold storage and transplantation-induced mitochondrial and renal injury
- Aberrant activation of the complement system in renal grafts is mediated by cold storage
- Aberrant activation of the complement system in renal grafts is mediated by cold storage
- Cold Storage Followed by Transplantation Induces Interferon-Gamma and STAT-1 in Kidney Grafts
- Cold Storage Followed by Transplantation Induces Interferon-Gamma and STAT-1 in Kidney Grafts
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
- Cold Storage Followed by Transplantation Induces Immunoproteasome in Rat Kidney Allografts: Inhibition of Immunoproteasome Does Not Improve Function
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