Biography and Research Information
OverviewAI-generated summary
A. Moerman's research has focused on molecular mechanisms underlying neurological disorders and cellular signaling pathways. Their work includes investigating the role of reelin, a protein crucial for neuronal development, and its fragments in rescuing cognitive deficits in mouse models of reelin deficiency. Moerman has also explored the modulation of apolipoprotein E receptor-2 by various factors, including ApoE4 and amyloid β-peptide, in the context of Alzheimer’s disease pathogenesis.
Further research has involved the study of gene expression in fibroblasts, specifically in relation to cutaneous T-cell lymphoma. Moerman has also contributed to studies on diagnostic strategies for rare cardiovascular conditions, such as Fabry disease and hereditary transthyretin amyloidosis, using next-generation sequencing. Additionally, their work has involved the isolation of specific immune cells from Sézary syndrome patients for transcriptomic profiling and has examined trends in female authorship within scientific publications.
Metrics
- h-index: 21
- Publications: 60
- Citations: 1,306
Selected Publications
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Modulation of apolipoprotein E receptor-2 by ApoE4, amyloid β-peptide, reelin, and secreted amyloid precursor protein: a common point of impact in Alzheimer’s disease pathogenesis (2026)
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Central repeat fragment of reelin leads to active reelin intracellular signaling and rescues cognitive deficits in a mouse model of reelin deficiency (2023)
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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling (2021)
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Isolating Human Peripheral Blood Mononuclear Cells and CD4+ T cells from Sézary Syndrome Patients for Transcriptomic Profiling (2021)
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Normal and cancer fibroblasts differentially regulate TWIST1, TOX and cytokine gene expression in cutaneous T-cell lymphoma (2021)
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