Match tier
Listed
Presence
Current · Arkansas
Last published
2023
Sources
OpenAlex · ORCID
Refreshed
2026-08-15
C
Cynthia J.M. Kane
High Impact
Researcher
Also affiliated: Texas Tech University (2005); Dartmouth–Hitchcock Medical Center (2005); Eastern Washington University (1992); University of Arkansas Medical Center (1996–2014); TiGenix (Spain) (1992); Cellular Research (United States) (1992); Arkansas Department of Agriculture (2004); Texas Tech University Health Sciences Center (2005); Stanford University (1988–1991)
Faculty Researcher
26 h-index
56 pubs
2,441 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Cynthia J.M. Kane's research focuses on the neurobiological effects of ethanol exposure, particularly during critical developmental periods. Her work investigates how alcohol impacts neuroinflammation, myelination, and gene expression in the cerebellum and hippocampus, utilizing mouse models to study both fetal alcohol spectrum disorders (FASD) and alcohol use disorder (AUD).
Her recent publications explore the molecular signaling pathways, such as TLR4 and MyD88, involved in ethanol-induced neuroinflammation. Kane also examines the long-term consequences of developmental ethanol exposure on brain development and function, with a specific interest in cerebellar transcriptomic changes that may relate to disease onset. Her research group collaborates with other faculty members at the University of Arkansas for Medical Sciences, including Paul D. Drew, James C. Douglas, Tonya Rafferty, and Kalee N. Holloway, on shared publications.
Kane has an h-index of 26 and has authored 56 publications with over 2,400 citations. She is recognized as a highly cited researcher.
Metrics
- h-index: 26
- Publications: 56
- Citations: 2,441
Selected Publications
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Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling (2023)
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Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset (2023)
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Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression (2023)
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Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation (2022)
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Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders (2021)
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Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders (2021)
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Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period (2021)
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Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders (2021)
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Neuroinflammatory contribution of microglia and astrocytes in fetal alcohol spectrum disorders (2020)
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Prenatal Ethanol Exposure and Postnatal Environmental Intervention Alter Dopaminergic Neuron and Microglia Morphology in the Ventral Tegmental Area During Adulthood (2019)
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PPAR-γ agonists suppress neuroinflammation in a FASD animal model (2017)
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Protection against alcohol-induced neuronal and cognitive damage by the PPARγ receptor agonist pioglitazone (2017)
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Peroxisome Proliferator-Activated Receptor-γ Agonists: Potential Therapeutics for Neuropathology Associated with Fetal Alcohol Spectrum Disorders (2016)
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Inflammatory responses to alcohol in the CNS: nuclear receptors as potential therapeutics for alcohol-induced neuropathologies (2016)
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Alcohol and Neuroimmune Interactions (2016)
Collaboration Network
Top Collaborators
Paul D. Drew
University of Arkansas for Medical Sciences
8 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
Showing 5 of 8 shared publications
James C. Douglas
University of Arkansas for Medical Sciences
7 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
Showing 5 of 7 shared publications
Tonya Rafferty
University of Arkansas for Medical Sciences
7 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Showing 5 of 7 shared publications
Kalee N. Holloway
University of Arkansas for Medical Sciences
5 shared publications
In database
- Ethanol Induces Neuroinflammation in a Chronic Plus Binge Mouse Model of Alcohol Use Disorder via TLR4 and MyD88-Dependent Signaling
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
- Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset
- Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression
Victoria M. Niedzwiedz‐Massey
University of Arkansas for Medical Sciences
4 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol effects on cerebellar myelination in a postnatal mouse model of fetal alcohol spectrum disorders
Jennifer W. Johnson
University of Arkansas for Medical Sciences
2 shared publications
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
Ania K. Majewska
University of Rochester Medical Center (US)
2 shared publications
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
- Ethanol-induced cerebellar transcriptomic changes in a postnatal model of fetal alcohol spectrum disorders: Focus on disease onset
Marisa R. Pinson
Texas A&M University (US)
2 shared publications
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
- Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression
Rajesh C. Miranda
Texas A&M University (US)
2 shared publications
- Divergent and overlapping hippocampal and cerebellar transcriptome responses following developmental ethanol exposure during the secondary neurogenic period
- Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression
Kevin D. Phelan
University of Arkansas for Medical Sciences
1 shared publication
In database
- Ethanol modulation of cerebellar neuroinflammation in a postnatal mouse model of fetal alcohol spectrum disorders
P.A.L. Wight
University of Arkansas for Medical Sciences
1 shared publication
In database
- Ethanol modulation of hippocampal neuroinflammation, myelination, and neurodevelopment in a postnatal mouse model of fetal alcohol spectrum disorders
Michael D. Berquist
University of Arkansas for Medical Sciences
1 shared publication
In database
- Effects of chronic and binge ethanol administration on mouse cerebellar and hippocampal neuroinflammation
James J. Douglas
University of Arkansas for Medical Sciences (US)
1 shared publication
- Cerebellar Transcriptomic Analysis in a Chronic plus Binge Mouse Model of Alcohol Use Disorder Demonstrates Ethanol-Induced Neuroinflammation and Altered Glial Gene Expression
Similar Researchers
Based on overlapping research topics
Tonya Rafferty
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Disease Models, Animal
Immune Response and Inflammation
Cassie M. Chandler
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Immune Response and Inflammation
Substance Abuse Treatment and Outcomes
Jennifer W. Johnson
University of Arkansas for Medical Sciences
Disease Models, Animal
Immune Response and Inflammation
Substance Abuse Treatment and Outcomes
Kalee N. Holloway
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Immune Response and Inflammation
Genomics and Phylogenetic Studies
Paul D. Drew
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Disease Models, Animal
Immune Response and Inflammation
Christa Corley
University of Arkansas for Medical Sciences
Neuroscience and Neuropharmacology Research
Disease Models, Animal
Immune Response and Inflammation