Match tier Likely match
Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-03

Abigail L Zirbel

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Also affiliated: Clemson University (2024)

1 h-index 4 pubs 2 cited

Biography and Research Information

OverviewAI-generated summary

Abigail L Zirbel's research investigates the impact of nutrient deficiencies on cellular energy metabolism, specifically within muscle cells. Her work has focused on how iron depletion affects mitochondrial function, examining changes in protein levels related to oxidative phosphorylation and mitochondrial complexes. Zirbel has also explored the role of specific genes, such as SHMT2, and their interaction with folate deficiency in influencing mitochondrial dynamics and protein expression in C2C12 myoblast cells. Her publications include studies on energy metabolism under varying iron availability and the effects of genetic alterations on cellular adaptations. Zirbel collaborates with Joanna Fiddler and Makenzie A Tharpe at the University of Arkansas at Fayetteville, with whom she shares multiple publications.

Metrics

  • h-index: 1
  • Publications: 4
  • Citations: 2

Selected Publications

  • Transient MYC Mimicking the Exercise Response Orchestrates Multifaceted Skeletal Muscle Adaptations (2026)
    bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
  • Loss of SHMT2 and Folate Deficiency Impair Protein Levels Involved in Oxidative Phosphorylation, Folate Transport, and Mitochondrial Dynamics in Mouse C2C12 Myoblast Cells (2025)
    Current Developments in Nutrition DOI OpenAlex
  • Marginal Iron Depletion Impairs Mitochondrial Complex I Activity and Reduces NDUFB8 and ISCU Protein Levels in Mouse C2C12 Myoblast Cells (2025)
    Current Developments in Nutrition DOI OpenAlex

View all publications on OpenAlex →

Collaboration Network

22 Collaborators 9 Institutions 2 Countries

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