S. Jill James

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UAMS primary UA Little Rock NCTR

Also affiliated: Arkansas Children's Hospital (2003–2017); United States Food and Drug Administration (1994–2002); NewYork–Presbyterian Brooklyn Methodist Hospital (2003); University Hospital Centre Zagreb (2004); University of British Columbia (2003–2007); University of Illinois Urbana-Champaign (2002); University of California, Los Angeles (1990–1993); Duke University (2011); George Washington University (2004); Vanderbilt University (2004); Cornell University (2003); University of Arkansas Medical Center (2005); Veterans Health Administration (2004); University of Florida (2011); United States Public Health Service (1994); Fred Hutch Cancer Center (2011); VA West Los Angeles Medical Center (1988–1991); National Center for Tumor Diseases (2011); University of Tampere (2002); UCLA Jonsson Comprehensive Cancer Center (1993); Arkansas Children's Research Institute (2003–2020); University of California, Davis (1996–2002); Vanderbilt University Medical Center (2004); University of California, Berkeley (2011)

68 h-index 158 pubs 14,414 cited

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ORCID

OverviewAI-generated summary

S. Jill James' research focuses on the intersection of metabolism, epigenetics, and specific health conditions, particularly in pediatric populations. Her work has investigated the role of oxidative stress and methylation capacity in children diagnosed with autism spectrum disorder, exploring metabolic biomarkers and genetic associations. Publications include studies on the relationship between plasma homocysteine, S-adenosylhomocysteine, and DNA hypomethylation, suggesting potential epigenetic mechanisms underlying homocysteine-related pathologies.

Further research has examined oxidative damage, inflammation, and glutathione status in the autism brain, as well as explored oxidative stress, inflammation, and treatment response in major depressive disorder. Her investigations also include the presence of cerebral folate receptor autoantibodies in autism spectrum disorder. James has a significant publication record with a high h-index and numerous citations, indicating a substantial body of work in her research areas. She collaborates with Stepan Melnyk on shared publications.

Metrics

h-index: 68
Publications: 158
Citations: 14,414

Selected Publications

The association between prenatal oxidative stress levels measured by isoprostanes and offspring neurodevelopmental outcomes at 36 months (2024)

Brain Behavior & Immunity - Health 7 citations DOI OpenAlex
Examining associations between prenatal biomarkers of oxidative stress and ASD-related outcomes using quantile regression (2022)

Journal of Autism and Developmental Disorders 9 citations DOI OpenAlex
Correction to: Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder (2021)

Molecular Autism 5 citations DOI OpenAlex
Randomized controlled trial of sulforaphane and metabolite discovery in children with Autism Spectrum Disorder (2021)

Molecular Autism 110 citations DOI OpenAlex
Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)

Research Square DOI OpenAlex
Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)

Research Square DOI OpenAlex
Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)

Research Square DOI OpenAlex
Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)

Research Square DOI OpenAlex
Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)

Research Square DOI OpenAlex
Altered Metabolism of Mothers of Young Children with Autism Spectrum Disorder: A Case Control Study (2020)

Research Square (Research Square) DOI OpenAlex
Altered metabolism of mothers of young children with Autism Spectrum Disorder: a case control study (2020)

BMC Pediatrics 25 citations DOI OpenAlex
Expression Changes in Epigenetic Gene Pathways Associated With One‐Carbon Nutritional Metabolites in Maternal Blood From Pregnancies Resulting in Autism and Non‐Typical Neurodevelopment (2020)

Autism Research 18 citations DOI OpenAlex
Expression changes in immune and epigenetic gene pathways associated with nutritional metabolites in maternal blood from pregnancies resulting in autism and atypical neurodevelopment (2020)

bioRxiv (Cold Spring Harbor Laboratory) DOI OpenAlex
Comparison of Three Clinical Trial Treatments for Autism Spectrum Disorder Through Multivariate Analysis of Changes in Metabolic Profiles and Adaptive Behavior (2018)

Frontiers in Cellular Neuroscience 21 citations DOI OpenAlex
Maternal metabolic profile predicts high or low risk of an autism pregnancy outcome (2018)

Research in Autism 35 citations DOI OpenAlex