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Presence Current · Arkansas
Last published 2020
Sources OpenAlex · ORCID
Refreshed 2026-10-07

Shi J. Liu

Assistant Professor

Also affiliated: University of Arkansas Medical Center (2019)

14 h-index 22 pubs 662 cited

  • Animals
  • Male
  • Rats
  • Rats, Sprague-Dawley
  • Heart Ventricles
  • Myocytes, Cardiac
  • Myocardial Contraction
  • Myocardium
  • Patch-Clamp Techniques
  • Female
  • Membrane Potentials
  • Cells, Cultured
  • Calcium Channels, L-Type
  • Humans
  • Enzyme Activation

Biography and Research Information

OverviewAI-generated summary

Shi J. Liu's research investigates the physiological and molecular mechanisms underlying cardiac function and dysfunction in adult ventricular myocytes. His work has explored the impact of various inflammatory cytokines, such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α), on myocyte contractility and cellular integrity. Liu has studied the roles of specific signaling pathways, including JAK2/STAT3 and ERK1/2, in mediating cytokine-induced effects on nitric oxide synthase (iNOS) and mitochondrial function. Additionally, his research has examined age-associated changes in ion channel currents (K+ and Ca2+) within rat ventricular myocytes and the effects of specific cellular components like lysoplasmenylcholine on calcium cycling in rabbit myocytes. Collaborations with researchers at the University of Arkansas for Medical Sciences, including Rosalia C. M. Simmen, Charles Matthew Quick, Iad Alhallak, and Frank A. Simmen, have contributed to his publication record.

Metrics

  • h-index: 14
  • Publications: 22
  • Citations: 662

Positions

  • Assistant Professor publications 1998–2020
    University of Arkansas for Medical Sciences Institution web page

Selected Publications

  • Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells (2020)
    Reproductive Sciences 24 citations DOI OpenAlex
  • Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus (2019)
    Journal of Endocrinology 12 citations DOI OpenAlex
  • Cardioprotective action of the aqueous extract of Terminalia arjuna bark against toxicity induced by doxorubicin (2017)
    Phytomedicine 21 citations DOI OpenAlex
  • Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice (2016)
    Endocrine Related Cancer 8 citations DOI OpenAlex
  • PO-18 ULTRASOUND BIOMICROSCOPIC STUDY OF ARTERIES IN DETECTION OF DOXORUBICIN-INDUCED DISORDERS (2014)
    Artery Research 1 citation DOI OpenAlex
  • Short‐term estrogen depletion does not promote hypertension in mice (2013)
    The FASEB Journal DOI OpenAlex
  • Characterization of functional capacity of adult ventricular myocytes in long-term culture (2013)
    International Journal of Cardiology 9 citations DOI OpenAlex
  • The aqueous extract, not organic extracts, of Terminalia arjuna bark exerts cardiotonic effect on adult ventricular myocytes (2011)
    Phytomedicine 38 citations DOI OpenAlex
  • Inhibition of L-type Ca2+ channel current and negative inotropy induced by arachidonic acid in adult rat ventricular myocytes (2007)
    American Journal of Physiology-Cell Physiology 26 citations DOI OpenAlex
  • Proliferation of human breast cancer cells and anti‐cancer action of doxorubicin and vinblastine are independent of PKC‐α (2006)
    Journal of Cellular Biochemistry 8 citations DOI OpenAlex
  • TNF-α-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes (2006)
    Cytokine 55 citations DOI OpenAlex
  • Inhibition of sarcoplasmic reticular function by chronic interleukin‐6 exposure via iNOS in adult ventricular myocytes (2005)
    The Journal of Physiology 36 citations DOI OpenAlex
  • Both cGMP and peroxynitrite mediate chronic interleukin‐6‐induced negative inotropy in adult rat ventricular myocytes (2005)
    The Journal of Physiology 20 citations DOI OpenAlex
  • Alterations in Ca2+ cycling by lysoplasmenylcholine in adult rabbit ventricular myocytes (2003)
    American Journal of Physiology-Cell Physiology 34 citations DOI OpenAlex
  • Positive inotropic effect of ceramide in adult ventricular myocytes: mechanisms dissociated from its reduction in Ca2+influx (2003)
    American Journal of Physiology-Heart and Circulatory Physiology 16 citations DOI OpenAlex

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Collaboration Network

30 Collaborators 8 Institutions 1 Country

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