Shi J. Liu
Assistant Professor
Also affiliated: University of Arkansas Medical Center (2019)
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Shi J. Liu's research investigates the physiological and molecular mechanisms underlying cardiac function and dysfunction in adult ventricular myocytes. His work has explored the impact of various inflammatory cytokines, such as Interleukin-6 (IL-6) and Tumor Necrosis Factor-alpha (TNF-α), on myocyte contractility and cellular integrity. Liu has studied the roles of specific signaling pathways, including JAK2/STAT3 and ERK1/2, in mediating cytokine-induced effects on nitric oxide synthase (iNOS) and mitochondrial function. Additionally, his research has examined age-associated changes in ion channel currents (K+ and Ca2+) within rat ventricular myocytes and the effects of specific cellular components like lysoplasmenylcholine on calcium cycling in rabbit myocytes. Collaborations with researchers at the University of Arkansas for Medical Sciences, including Rosalia C. M. Simmen, Charles Matthew Quick, Iad Alhallak, and Frank A. Simmen, have contributed to his publication record.
Metrics
- h-index: 14
- Publications: 22
- Citations: 662
Positions
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Assistant Professor publications 1998–2020University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells (2020)
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Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus (2019)
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Cardioprotective action of the aqueous extract of Terminalia arjuna bark against toxicity induced by doxorubicin (2017)
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Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice (2016)
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PO-18 ULTRASOUND BIOMICROSCOPIC STUDY OF ARTERIES IN DETECTION OF DOXORUBICIN-INDUCED DISORDERS (2014)
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Short‐term estrogen depletion does not promote hypertension in mice (2013)
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Characterization of functional capacity of adult ventricular myocytes in long-term culture (2013)
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The aqueous extract, not organic extracts, of Terminalia arjuna bark exerts cardiotonic effect on adult ventricular myocytes (2011)
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Inhibition of L-type Ca2+ channel current and negative inotropy induced by arachidonic acid in adult rat ventricular myocytes (2007)
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Proliferation of human breast cancer cells and anti‐cancer action of doxorubicin and vinblastine are independent of PKC‐α (2006)
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TNF-α-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes (2006)
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Inhibition of sarcoplasmic reticular function by chronic interleukin‐6 exposure via iNOS in adult ventricular myocytes (2005)
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Both cGMP and peroxynitrite mediate chronic interleukin‐6‐induced negative inotropy in adult rat ventricular myocytes (2005)
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Alterations in Ca2+ cycling by lysoplasmenylcholine in adult rabbit ventricular myocytes (2003)
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Positive inotropic effect of ceramide in adult ventricular myocytes: mechanisms dissociated from its reduction in Ca2+influx (2003)
Collaboration Network
Top Collaborators
- JAK2/STAT3, Not ERK1/2, Mediates Interleukin-6-induced Activation of Inducible Nitric-oxide Synthase and Decrease in Contractility of Adult Ventricular Myocytes
- TNF-α-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes
- Inhibition of sarcoplasmic reticular function by chronic interleukin‐6 exposure via iNOS in adult ventricular myocytes
- Alterations in Ca2+ cycling by lysoplasmenylcholine in adult rabbit ventricular myocytes
- α1-Adrenergic activation of L-type Ca current in rat ventricular myocytes: perforated patch-clamp recordings
Showing 5 of 8 shared publications
- JAK2/STAT3, Not ERK1/2, Mediates Interleukin-6-induced Activation of Inducible Nitric-oxide Synthase and Decrease in Contractility of Adult Ventricular Myocytes
- Inhibition of sarcoplasmic reticular function by chronic interleukin‐6 exposure via iNOS in adult ventricular myocytes
- Both cGMP and peroxynitrite mediate chronic interleukin‐6‐induced negative inotropy in adult rat ventricular myocytes
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus
- Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus
- Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells
- Co-morbidity of type 1 diabetes and endometriosis: bringing a new paradigm into focus
- Both cGMP and peroxynitrite mediate chronic interleukin‐6‐induced negative inotropy in adult rat ventricular myocytes
- TNF-α-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes
- TNF-α-induced impairment of mitochondrial integrity and apoptosis mediated by caspase-8 in adult ventricular myocytes
- Proliferation of human breast cancer cells and anti‐cancer action of doxorubicin and vinblastine are independent of PKC‐α
- Proliferation of human breast cancer cells and anti‐cancer action of doxorubicin and vinblastine are independent of PKC‐α
- The aqueous extract, not organic extracts, of Terminalia arjuna bark exerts cardiotonic effect on adult ventricular myocytes
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