Rosalia C. M. Simmen
Researcher
Also affiliated: College of Wooster (1988); Arkansas Children's Hospital (2012–2014); Agricultural Research Service (1997); Kansas State University (1997); University of Arkansas Medical Center (2015); Ohio Department of Agriculture (1990); Chinju National University of Education (1998); University of Florida (1989–2006); Winthrop Rockefeller Foundation (2012–2025); Roman L. Hruska U.S. Meat Animal Research Center (1997); Arkansas Children's Nutrition Center (2005–2013); The Ohio State University (1988–1990); Nagoya University (2013); University of Missouri (1990)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Rosalia C. M. Simmen's research investigates the molecular and physiological mechanisms underlying metabolic disorders, reproductive health conditions, and oncogenesis. Her work has explored the role of specific genes, such as Malic Enzyme 1 (ME1) and Krüppel-like Factors (KLF9 and KLF13), in promoting adiposity, hepatic steatosis, and inflammation in animal models. She has also examined the interplay between diet and disease development, including the effects of high-fat diets on endometriosis progression in mice and the regulation of breast adipose tissue in premenopausal women.
Dr. Simmen's research also extends to the heritability of metabolic traits in livestock, as evidenced by her long-term study on serum Insulin-like Growth Factor I concentration in Angus beef cattle. She has published on the co-existence of diabetes and endometriosis in reproductive-age women, suggesting potential links to disease progression. Her scholarship metrics include an h-index of 29, with over 2,400 citations across 97 publications, designating her as a highly cited researcher. She actively collaborates with colleagues at the University of Arkansas for Medical Sciences, including Iad Alhallak and Frank A. Simmen.
Metrics
- h-index: 29
- Publications: 97
- Citations: 2,499
Selected Publications
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Characterizing Human Milk RNA Degradation Over Time to Optimize Storage of Human Milk for RNA Quality (2026)
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Transcriptional drivers and endocrine disorders (2025)
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Unveiling myometrial SP/Krüppel-like factors as drivers of parturition: insights from transcriptional and endocrine regulatory networks (2025)
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Endometriosis and Endometriosis-Associated Tumors (2025)
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Heritability and Correlation Estimates for Serum Insulin-like Growth Factor I Concentration, Weight, Weight Gain, and Height in Angus Beef Cattle in a Long-Term Divergent Selection Study for Serum Insulin-like Growth Factor I (1989 to 2017) (2024)
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Endometriosis and Endometriosis-Associated Tumors (2024)
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Krüppel-like Factor-9 and Krüppel-like Factor-13: Highly Related, Multi-Functional, Transcriptional Repressors and Activators of Oncogenesis (2023)
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Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice (2023)
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A Pilot Study on the Co-existence of Diabetes and Endometriosis in Reproductive-Age Women: Potential for Endometriosis Progression (2023)
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Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet (2022)
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Lesion Genotype Modifies High-Fat Diet Effects on Endometriosis Development in Mice (2021)
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Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10 (2021)
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Co-Morbidity of Type 1 Diabetes Promotes Endometriosis Status-A Pilot Study (2021)
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Metformin regulation of progesterone receptor isoform‑B expression in human endometrial cancer cells is glucose‑dependent (2020)
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Malic enzyme 1 (ME1) in the biology of cancer: it is not just intermediary metabolism (2020)
Collaboration Network
Top Collaborators
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Krüppel-like Factor-9 and Krüppel-like Factor-13: Highly Related, Multi-Functional, Transcriptional Repressors and Activators of Oncogenesis
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- A Pilot Study on the Co-existence of Diabetes and Endometriosis in Reproductive-Age Women: Potential for Endometriosis Progression
- Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10
Showing 5 of 7 shared publications
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Krüppel-like Factor-9 and Krüppel-like Factor-13: Highly Related, Multi-Functional, Transcriptional Repressors and Activators of Oncogenesis
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10
- Lesion Genotype Modifies High-Fat Diet Effects on Endometriosis Development in Mice
Showing 5 of 6 shared publications
- A Pilot Study on the Co-existence of Diabetes and Endometriosis in Reproductive-Age Women: Potential for Endometriosis Progression
- Endometriosis and Endometriosis-Associated Tumors
- Co-Morbidity of Type 1 Diabetes Promotes Endometriosis Status-A Pilot Study
- Endometriosis and Endometriosis-Associated Tumors
- A Pilot Study on the Co-existence of Diabetes and Endometriosis in Reproductive-Age Women: Potential for Endometriosis Progression
- Co-Morbidity of Type 1 Diabetes Promotes Endometriosis Status-A Pilot Study
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Lesion Genotype Modifies High-Fat Diet Effects on Endometriosis Development in Mice
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Lesion Genotype Modifies High-Fat Diet Effects on Endometriosis Development in Mice
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Endometriosis and Endometriosis-Associated Tumors
- Endometriosis and Endometriosis-Associated Tumors
- Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10
- Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10
- Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10
- Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10
- Breast adipose regulation of premenopausal breast epithelial phenotype involves interleukin 10
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
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