Ping-Ching Hsu
Associate Professor
University of Arkansas for Medical Sciences
faculty
Environmental Health Sciences, College of Public Health
Research Areas
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Biography and Research Information
OverviewAI-generated summary
Ping-Ching Hsu is an Associate Professor in Environmental Health Sciences at the University of Arkansas for Medical Sciences. Her research focuses on the intersection of environmental exposures, health outcomes, and the application of advanced analytical techniques. Dr. Hsu has published extensively on the health impacts of pesticide exposure, including a systematic review on its association with colorectal cancer risk and incidence, and a geospatial assessment of pesticide concentration in ambient air and colorectal cancer incidence in Arkansas. Her work also investigates the role of metabolomics in identifying biomarkers for various health conditions, such as doxorubicin-induced cardiotoxicity and maternal health outcomes following pregnancies affected by congenital heart defects.
Dr. Hsu's research group also examines substance use, including a study on the validation of self-reported electronic nicotine delivery system use. She has received significant federal funding from the NIH/National Institute of Environmental Health Sciences as Principal Investigator for two awards totaling $778,801. These grants support the Arkansas Rural Community Health-Healthy Environmental Research (ARCH-HER) Study and efforts to promote scientific and workforce diversity within this study, focusing on mother-daughter pairs. Her scholarly contributions are reflected in her h-index of 9 and over 360 citations across 73 publications.
Metrics
- h-index: 9
- Publications: 73
- Citations: 360
Selected Publications
- Association of DNA methyltransferase polymorphisms with breast cancer: a nested case‒control study of the Arkansas Rural Community Health study (2026) DOI
- Modified tumor uptake and biodistribution of nanoparticles coated with small extracellular vesicle membranes derived from distinct tumor cell lines (2026) DOI
- DNA Methylation in Lung Cancer: Predictive Biomarkers for Effective Immunotherapy (2025) DOI
- Abstract A058: Plasma folate and folic acid status in relation to prostate cancer aggressiveness: Insights into racial disparities from the PCaP study (2025) DOI
- Carcinogenic air pollutants and breast cancer risk in the Arkansas rural community health study: A nested case-control study (2025) DOI
- A Case-Control Study of Dietary Choline Intake and Risk of Colorectal Cancer Modified by Dietary B-Vitamin Intake (2024) DOI
- Organic Food Consumption and the Risk of Type 2 Diabetes in the Sister Study (2024) DOI
- Cigarette smoking and prostate cancer aggressiveness among African and European American men (2024) DOI
- Abstract 7005: Distinct DNA methylation patterns between early-onset and average-onset colorectal cancer patients (2024) DOI
- Abstract 3625: Metabolic phenotypes of doxorubicin-induced cardiotoxicity in breast cancer patients (2024) DOI
- Stem Cell Theory of Cancer: Clinical Implications for Cellular Metabolism and Anti-Cancer Metabolomics (2024) DOI
- Saliva and Urine Sampling to Quantify Trace Metal Exposure for Epidemiologic Studies (2023) DOI
- Current Practices in LC-MS Untargeted Metabolomics: A Scoping Review on the Use of Pooled Quality Control Samples (2023) DOI
- Abstract B096: Cigarette smoking and prostate cancer aggressiveness among African and European American men (2023) DOI
- Increased Utilization of Low-Dose CT for Lung Cancer Screening at an Arkansas Community Oncology Clinic (2023) DOI
Federal Grants 2 $778,801 total
Arkansas Rural Community Health-Healthy Environmental Research (ARCH-HER) Study
Research Interests
My laboratory is interested in biomarker discovery using global metabolite profiling (metabolomics). We use metabolomics to identify the “metabotype” that are consisting of oxidized lipids and metabolites in patients and animal models hoping to find early indicators of chemotherapy-induced cardiotoxicity and cognitive impairments in breast cancer patients. We also work on addressing the issue of cigarette smoking especially menthol cigarette smoking that’s contributing to the disparity of lethal prostate cancer in African-Americans, by identifying smoking-related metabolomics patterns associated with highly aggressive prostate cancer in African-Americans compared to European-Americans.
Grants & Funding
- Feasibility study to improve the assessment of cancer treatment-related cognitive impairment. Winthrop P. Rockefeller Team Science Pilot Award Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University Principal Investigator
- Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs NIH/Nat. Inst. of Environmental Health Sciences Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University Principal Investigator
- Long-term effects of electronic cigarettes on brain health NIH/Nat. Inst. on Drug Abuse - Pass Through: Wake Forest University Principal Investigator
- Metabolomics of Menthol Cigarette Smoking and Risk for Aggressive Prostate Cancer Among African American Men US Department of Defense Principal Investigator
- Promoting scientific and workforce diversity by enriching the Arkansas Rural Community Health Study (ARCH) among Mother-Daughter Pairs NIH/Nat. Inst. of Environmental Health Sciences Principal Investigator
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