Renny S. Lan
Assistant Professor
Also affiliated: National Institutes of Health (2009); Arkansas Children's Hospital (2021–2025); Georgetown University (2009–2012); University of Arkansas Medical Center (2020–2026); Georgetown University Medical Center (2012); National Institute of Diabetes and Digestive and Kidney Diseases (2009); Ohio University (2015); Arkansas Children's Nutrition Center (2020–2026); The Ohio State University (2015–2017)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Renny S. Lan investigates the intersection of host physiology, microbiome, and disease, with a focus on metabolomics and mass spectrometry techniques. Their work includes studies on the gut microbiome's role in early life development, particularly in relation to maternal obesity and infant growth. Lan also studies the impact of exercise on xenometabolites in both lean and obese adults, and the influence of specific genetic mutations on disease progression, such as polycystic kidney disease in mice. Additionally, Lan's research explores the molecular mechanisms underlying bone mass regulation, involving osteoclast mitochondria and iron uptake. Their publications also delve into the optimization of mass spectrometric parameters for untargeted metabolomics and the critical roles of specific bacterial enzymes in pathogen virulence. Lan has published 58 papers with 940 citations and an h-index of 13, and collaborates with researchers at the University of Arkansas for Medical Sciences, including Ping-Ching Hsu and Lindsay Pack.
Metrics
- h-index: 14
- Publications: 60
- Citations: 966
Selected Publications
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Lactiplantibacillus plantarum promotes intestinal goblet cell differentiation via indole-3-lactic acid–AHR signaling in pigs (2026)
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Metabolic phenotypes of doxorubicin-induced cardiotoxicity among patients with breast cancer (2026)
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Integrating fingerprint prediction and physicochemical property filtering to annotate unknown metabolites from high-resolution MS/MS spectra (2026)
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Metabolic Reprogramming Induced by Mitochondrial Citrate Carrier Deletion Mitigates Antibiotics-Induced Acute Tubular Injury (2026)
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Carnitine deficiency alters fuel metabolism and voluntary wheel running in mice (2026)
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Circulating short- and medium-chain fatty acids in pregnancy and associations with maternal and infant metabolism, inflammation, and body composition (2026)
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Xenometabolomics reveals metabolic functional guilds unique to specific inulin subtypes in human gut microbiota cultures (2025)
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Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity (2025)
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Associations Between Serum Gut-Derived Tryptophan Metabolites and Cardiovascular Health Markers in Adolescents with Obesity (2025)
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Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery (2025)
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A narrative review of metabolomics approaches in identifying biomarkers of doxorubicin-induced cardiotoxicity (2025)
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Evaluation of ion source parameters and liquid chromatography methods for plasma untargeted metabolomics using orbitrap mass spectrometer (2025)
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Evaluation of Ion Source Parameters and Liquid Chromatography Methods for Plasma Untargeted Metabolomics Using Orbitrap Mass Spectrometer (2024)
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Associations between maternal microbiome, metabolome and incidence of low-birth weight in Guatemalan participants from the Women First Trial (2024)
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Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues (2024)
Collaboration Network
Top Collaborators
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- The Diadenylate Cyclase CdaA Is Critical for Borrelia turicatae Virulence and Physiology
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Elamipretide treatment during pregnancy ameliorates the progression of polycystic kidney disease in maternal and neonatal mice with PKD1 mutations
- Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
Showing 5 of 11 shared publications
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Exercise training modifies xenometabolites in gut and circulation of lean and obese adults
- Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
- Colonic epithelial hypoxia remains constant during the progression of diabetes in male UC Davis type 2 diabetes mellitus rats
- Beyond the Known Metabolome: Predictive Strategies for Dark Matter Discovery
Showing 5 of 8 shared publications
- Optimization of Mass Spectrometric Parameters in Data Dependent Acquisition for Untargeted Metabolomics on the Basis of Putative Assignments
- Associations Between Serum Gut-Derived Tryptophan Metabolites and Cardiovascular Health Markers in Adolescents with Obesity
- Evaluation of ion source parameters and liquid chromatography methods for plasma untargeted metabolomics using orbitrap mass spectrometer
- Ion Source Optimization and Lc Separation Method Development for Comprehensive Untargeted Metabolomics Using Orbitrap Mass Spectrometer
- The Gut Microbiome Across the Murine Lifespan: Impact of Diet and Its Association With Inflammation, Lipids, Liver Cancer, and Lifespan
Showing 5 of 6 shared publications
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Associations Between Serum Gut-Derived Tryptophan Metabolites and Cardiovascular Health Markers in Adolescents with Obesity
- Circulating long-chain acylcarnitine concentrations are not affected by exercise training in pregnant women with obesity
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
- Integrating fingerprint prediction and physicochemical property filtering to annotate unknown metabolites from high-resolution MS/MS spectra
- Optimization of Mass Spectrometric Parameters in Data Dependent Acquisition for Untargeted Metabolomics on the Basis of Putative Assignments
- Evaluation of ion source parameters and liquid chromatography methods for plasma untargeted metabolomics using orbitrap mass spectrometer
- Ion Source Optimization and Lc Separation Method Development for Comprehensive Untargeted Metabolomics Using Orbitrap Mass Spectrometer
- Evaluation of Ion Source Parameters and Liquid Chromatography Methods for Plasma Untargeted Metabolomics Using Orbitrap Mass Spectrometer
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Phosphoproteomics Provides Novel Insights into the Response of Primary Acute Lymphoblastic Leukemia Cells to Microtubule Depolymerization in G1 Phase of the Cell Cycle
- Associations between maternal obesity and offspring gut microbiome in the first year of life
- Infant intakes of human milk branched chain amino acids are negatively associated with infant growth and influenced by maternal body mass index
- Circulating long-chain acylcarnitine concentrations are not affected by exercise training in pregnant women with obesity
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
- Exercise training modifies xenometabolites in gut and circulation of lean and obese adults
- Novel odd-chain cyclopropane fatty acids: detection in a mammalian lipidome and uptake by hepatosplanchnic tissues
- Prenatal Exercise Training Alters Plasma Metabolite Responses To Acute Exercise In Pregnant Women With Obesity
- Xenometabolomics reveals metabolic functional guilds unique to specific inulin subtypes in human gut microbiota cultures
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
- Author response: Transferrin receptor 1-mediated iron uptake regulates bone mass in mice via osteoclast mitochondria and cytoskeleton
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