Daniel R. Doerge
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Researcher
Also affiliated: University of Southern California (2007); Center for Food Safety and Applied Nutrition (2008); National Institutes of Health (2005); Environmental Protection Agency (1999); Research Triangle Park Foundation (1999); United States Food and Drug Administration (1995–2022); University of Hawaii System (1986–1992); University of British Columbia (1996); University of Illinois Urbana-Champaign (2005–2011); Urbana University (2007); Collins College (2007); University of Florida (1982–1985); Honolulu University (1988–1991); National Institute of Environmental Health Sciences (2000); Southwestern Medical Center (1997); Orszagos Kornyezetegeszsegugyi Intezet (1998–2005); National Cancer Institute (1998–2005); Food and Drug Administration (2003–2015); National Center for Epidemiology (2005); University of Missouri (2007); University of California, Davis (1979–1982); The University of Texas Southwestern Medical Center (1997)
Faculty Researcher
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Daniel R. Doerge's research focuses on the toxicological effects and metabolic pathways of various compounds, with a particular emphasis on their impact in animal models, including rats and mice. His work has investigated the toxicokinetics of polyfluorinated compounds in pregnant and nonpregnant rats, examining how the body processes these substances following oral exposure. Additionally, Doerge has studied the effects of isoflavones, such as genistein and isoliquiritigenin, on biological processes. His research on genistein has explored its influence on mammary tumor response to tamoxifen in rats, while isoliquiritigenin has been examined for its role in decreasing bone resorption and osteoclast differentiation.
Doerge's extensive publication record, with over 339 publications and a citation count exceeding 19,000, indicates a significant contribution to the field of toxicology and pharmacology. He is recognized as a highly cited researcher. His collaborations include researchers from the National Center for Toxicological Research, such as Volodymyr Tryndyak, Frederick A. Beland, Michelle M. Vanlandingham, and Mona I. Churchwell, with whom he has co-authored publications. Doerge maintains an active laboratory website to share his research findings.
Metrics
- h-index: 76
- Publications: 339
- Citations: 19,684
Selected Publications
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Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound (2023)
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Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation (2022)
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Characterizing biopersistence potential of the metabolite 5:3 fluorotelomer carboxylic acid after repeated oral exposure to the 6:2 fluorotelomer alcohol (2020)
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A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results (2019)
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Advancing human health risk assessment (2019)
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Metabolism and disposition of arsenic species from controlled dosing with dimethylarsinic acid (DMAV) in adult female CD-1 mice. V. Toxicokinetic studies following oral and intravenous administration (2019)
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Exposure to Arsenite in CD-1 Mice during Juvenile and Adult Stages: Effects on Intestinal Microbiota and Gut-Associated Immune Status (2018)
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Metabolism and pharmacokinetics of zearalenone following oral and intravenous administration in juvenile female pigs (2017)
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Lifetime Genistein Intake Increases the Response of Mammary Tumors to Tamoxifen in Rats (2017)
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Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study (2016)
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Irreversible down-regulation of miR-375 in the livers of Fischer 344 rats after chronic furan exposure (2016)
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Furan-induced transcriptomic and gene-specific DNA methylation changes in the livers of Fischer 344 rats in a 2-year carcinogenicity study (2016)
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Urine and serum biomonitoring of exposure to environmental estrogens II: Soy isoflavones and zearalenone in pregnant women (2016)
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Urine and serum biomonitoring of exposure to environmental estrogens I: Bisphenol A in pregnant women (2016)
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Pharmacokinetics of bisphenol A in humans following a single oral administration (2015)
Collaboration Network
Top Collaborators
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Isoliquiritigenin Decreases Bone Resorption and Osteoclast Differentiation
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
- Evaluating the toxicokinetics of some metabolites of a C6 polyfluorinated compound, 6:2 fluorotelomer alcohol in pregnant and nonpregnant rats after oral exposure to the parent compound
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