Frederick F. Lang
Researcher
University of Arkansas for Medical Sciences
faculty
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Biography and Research Information
OverviewAI-generated summary
Frederick F. Lang is a faculty member at the University of Arkansas for Medical Sciences. His research program focuses on oncological patient care, specifically investigating treatment strategies for brain tumors and hematological conditions in cancer patients. Lang has published work on the management of chronic subdural hematoma in oncological patients, comparing surgical drainage with middle meningeal artery embolization. His publications also address the role of oncogenic drivers in shaping the tumor microenvironment of human gliomas and the impact of brain metastases on patient survival in non-small cell lung cancer treated with immune checkpoint inhibitors.
Lang is currently PI on a $76,500 NIH/National Cancer Institute grant to develop immunocompetent melanoma brain metastases organoids. His work also includes a phase 1/2 trial on oncolytic DNX-2401 virotherapy combined with pembrolizumab for recurrent glioblastoma. Further research interests include the molecular and clinical determinants of response to immunotherapy in high-grade glioma and the surgical management of infiltrative gliomas. Lang's scholarship metrics include an h-index of 6, with 14 total publications and over 1,055 citations.
Metrics
- h-index: 6
- Publications: 14
- Citations: 1,055
Selected Publications
- Impact of baseline brain metastases on survival and CNS progression in NSCLC patients treated with immune checkpoint inhibitors in real-world studies: a systematic review and meta-analysis (2026) DOI
Federal Grants 1 $76,500 total
Development of immunocompetent melanoma brain metastases organoids
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