Maria Theresa E. Montales
Researcher
Also affiliated: Arkansas Children's Hospital (2013–2014); University of Arkansas Medical Center (2015–2017); Winthrop Rockefeller Foundation (2015); Arkansas Children's Nutrition Center (2011–2013)
Faculty Researcher
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Maria Theresa E. Montales investigates the molecular mechanisms underlying metabolic disorders and cancer. Her research has focused on the role of specific enzymes and proteins in conditions such as obesity and hepatocellular carcinoma. Recent publications include studies on how Malic Enzyme 1 (ME1) contributes to adiposity and hepatic steatosis in mice, and how Krüppel-like Factor 9 (KLF9) can suppress oxidative stress in mice fed a high-fat diet, potentially impacting hepatocellular carcinoma development.
Montales's work also delves into the cellular pathways involving PTEN and Wnt1 proteins, with a focus on their roles in cancer progression. Her research utilizes animal models, including transgenic mice, and cell culture techniques to explore these complex biological processes. Her scholarship metrics indicate a body of work with an h-index of 11 and over 1,900 citations across 20 publications. She collaborates with researchers at the University of Arkansas for Medical Sciences, including Frank A. Simmen and Iad Alhallak.
Metrics
- h-index: 11
- Publications: 20
- Citations: 1,977
Selected Publications
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Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice (2023)
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Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet (2022)
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Metformin Promotes Anti-tumor Biomarkers in Human Endometrial Cancer Cells (2020)
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Clinical Review of Antidiabetic Drugs: Implications for Type 2 Diabetes Mellitus Management (2017)
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Metabolic history impacts mammary tumor epithelial hierarchy and early drug response in mice (2016)
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HIV-Associated TB Syndemic: A Growing Clinical Challenge Worldwide (2015)
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Metformin and soybean-derived bioactive molecules attenuate the expansion of stem cell-like epithelial subpopulation and confer apoptotic sensitivity in human colon cancer cells (2015)
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Tuberculosis reinfection in a pregnant cystic fibrosis patient (2015)
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Mycobacterium tuberculosis infection in a HIV-positive patient (2015)
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Maternal high fat diet promotion of mammary tumor risk in adult progeny is associated with early expansion of mammary cancer stem‐like cells and increased maternal oxidative environment (2013)
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Maternal metabolic changes with dietary intake of blueberry during pregnancy and lactation predispose adult progeny to lower mammary tumor growth rate (2013)
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Dietary suppression of the mammary CD29hiCD24+ epithelial subpopulation and its cytokine/chemokine transcriptional signatures modifies mammary tumor risk in MMTV-Wnt1 transgenic mice (2013)
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Soy Foods: Towards the Development of Novel Therapeutics for Breast Cancer (2013)
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Genistein‐mediated inhibition of mammary stromal adipocyte differentiation limits expansion of mammary stem/progenitor cells by paracrine signaling (2012)
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The soybean peptide lunasin promotes apoptosis of mammary epithelial cells via induction of tumor suppressor PTEN: similarities and distinct actions from soy isoflavone genistein (2012)
Collaboration Network
Top Collaborators
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Krüppel-like Factor 9 (KLF9) Suppresses Hepatocellular Carcinoma (HCC)-Promoting Oxidative Stress and Inflammation in Mice Fed High-Fat Diet
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
- Malic Enzyme 1 (ME1) Promotes Adiposity and Hepatic Steatosis and Induces Circulating Insulin and Leptin in Obese Female Mice
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