Match tier
Listed
Presence
Current · Arkansas
Last published
2025
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
A
Ambika Verma
Assistant Staff Scientist
Geriatrics, College of Medicine
10 h-index
31 pubs
413 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Ambika Verma investigates the molecular mechanisms underlying neuroinflammatory diseases, with a particular focus on the role of mitochondria and inflammasomes. Her research explores how bacterial components, such as lipopolysaccharides from *Porphyromonas gingivalis*, trigger oxidative stress and mitochondrial dysfunction, contributing to neuroinflammation. Verma's work has also examined the impact of valine supplementation on mitochondrial function and protection against oxidative stress. She has investigated the regulatory role of Rho/SRF pathway inhibitors on mitochondrial functions and has published on how neutrophil inflammasomes sense translocated bacterial effectors. Her recent publications include studies on the proteomic analysis of lipopolysaccharide-induced neuroinflammation and the role of caspase-4 dependent noncanonical inflammasome activation in Alzheimer's disease pathologies. Verma holds a h-index of 13 with 61 total publications and 539 citations.
Metrics
- h-index: 10
- Publications: 31
- Citations: 413
Positions
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Assistant Staff Scientist 2025–presentUniversity of Arkansas for Medical Sciences Geriatrics, College of Medicine Institutional directory
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Post-doctoral Fellow 2021–2025University of Arkansas for Medical Sciences Department of Geriatrics ORCID
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Research Assistant 2019–2021University of Arkansas for Medical Sciences Microbiology and Immunology ORCID
Selected Publications
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Biology of Aging I Antisense Oligonucleotide-Mediated SRF Reduction Ameliorates Mitochondrial Dysfunction in Cardiac Aging (2025)
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P. gingivalis-LPS Activates the Alzheimer’s Disease-Associated Amyloid Secretase Pathway via Caspase-4 (2025)
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Mitochondrial Dynamics in Aging Heart (2025)
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Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases (2025)
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Porphyromonas gingivalis-Lipopolysaccharide Induced Caspase-4 Dependent Noncanonical Inflammasome Activation Drives Alzheimer’s Disease Pathologies (2025)
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Cardiac-specific overexpression of serum response factor regulates age-associated decline in mitochondrial function (2025)
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CARDIAC SPECIFIC OVEREXPRESSION OF SERUM RESPONSE FACTOR ALTERS MITOCHONDRIAL STRUCTURE AND FUNCTION (2024)
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DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES (2024)
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DIFFERENTIAL MICRORNAS PROFILING OF MARSHALLESE IN ARKANSAS IS ASSOCIATED WITH CHRONIC DISEASES OF AGING (2024)
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P. GINGIVALIS-LPS PROMOTES AD/ADRD VIA CASPASE-4-MEDIATED NONCANONICAL INFLAMMASOME PATHWAY (2024)
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The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function (2024)
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Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells (2024)
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Deletion of Interleukin-1β Converting Enzyme Alters Mouse Cardiac Structure and Function (2024)
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Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome (2024)
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Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function (2024)
Collaboration Network
Top Collaborators
Pankaj Patyal
University of Arkansas for Medical Sciences
23 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 23 shared publications
Gohar Azhar
University of Arkansas for Medical Sciences
23 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 23 shared publications
Jeanne Y. Wei
University of Arkansas for Medical Sciences
23 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 23 shared publications
Xiaomin Zhang
Institute on Aging (US)
16 shared publications
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Proteomic analysis of P. gingivalis-Lipopolysaccharide induced neuroinflammation in SH-SY5Y and HMC3 cells
- Inhibitors of Rho/MRTF/SRF Transcription Pathway Regulate Mitochondrial Function
Showing 5 of 16 shared publications
Shakshi Sharma
Institute on Aging
9 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- Mitochondrial Dynamics in Aging Heart
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
Showing 5 of 9 shared publications
Yingni Che
Institute on Aging
6 shared publications
In database
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
Showing 5 of 6 shared publications
Changhoon Oh
University of Arkansas for Medical Sciences (US)
5 shared publications
- Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
- Shigella OspC3 suppresses murine cytosolic LPS sensing
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
- Caspase-11 Non-canonical Inflammasomes in the Lung
- Shigella OspC3 Suppresses Murine Cytosolic LPS Sensing
Youssef Aachoui
University of Arkansas for Medical Sciences (US)
5 shared publications
- Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
- Shigella OspC3 suppresses murine cytosolic LPS sensing
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
- Caspase-11 Non-canonical Inflammasomes in the Lung
- Shigella OspC3 Suppresses Murine Cytosolic LPS Sensing
Robert R. Wolfe
Institute on Aging
4 shared publications
In database
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
- EAAS AND WHEY PROTEIN MAY IMPROVE PHYSICAL FUNCTION OF OLDER ADULTS INDEPENDENTLY OF GUT MICROBIOME
Fathima S. Ameer
Institute on Aging
3 shared publications
In database
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- SIRTUIN 1 ISOFORMS DIFFERENTIALLY IMPACT MITOCHONDRIAL GENE EXPRESSION AND FUNCTION IN MUSCLE CELLS
Grishma KC
Institute on Aging
3 shared publications
In database
- Valine improves mitochondrial function and protects against oxidative stress
- P. gingivalis-LPS Induces Mitochondrial Dysfunction Mediated by Neuroinflammation through Oxidative Stress
- Rho/SRF Inhibitor Modulates Mitochondrial Functions
Amanda K. Pangle
Institute on Aging
3 shared publications
In database
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Short‐Term Ingestion of Essential Amino Acid Based Nutritional Supplements or Whey Protein Improves the Physical Function of Older Adults Independently of Gut Microbiome
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
Wei Zhang
University of Arkansas at Little Rock
3 shared publications
In database
- Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement verses whey protein in low physical functioning older adults
- Correction to: Differential plasma protein expression after ingestion of essential amino acid-based dietary supplement versus whey protein in low physical functioning older adults
- Differential microRNA profiling of the Marshallese population in Arkansas reveals a higher association with chronic diseases
Jyotsna Shrivastava
Institute on Aging
3 shared publications
In database
- The Role of Sirtuin-1 Isoforms in Regulating Mitochondrial Function
- Mitochondrial Dynamics in Aging Heart
- DIFFERENTIAL EFFECT OF SIRT1 ON MITOCHONDRIAL FUNCTION: INSIGHTS INTO MITOCHONDRIAL RESPIRATORY COMPLEXES
Edward A. Miao
Duke University (US)
2 shared publications
- Neutrophil Caspase-11 Is Essential to Defend against a Cytosol-Invasive Bacterium
- Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins
Similar Researchers
Based on overlapping research topics
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University of Arkansas for Medical Sciences
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