B
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
B. Suresh Kuarm's research focuses on the design, synthesis, and evaluation of novel chemical compounds with potential therapeutic applications. His work has explored the synthesis of various heterocyclic compounds, including thiadiazolidinones, selenadiazoles, quinazolinones, and quinoxalines. These compounds have been investigated for their antimicrobial, antitubercular, and neuroprotective properties. For example, one publication details how thiadiazolidinone (TDZD) analogs were found to inhibit aggregation-associated pathology in models of neurodegeneration and extend lifespan in *C. elegans*. Another study reports the synthesis of quinazolinone derivatives with notable antimicrobial and antitubercular activity. Kuarm has also investigated one-pot synthesis protocols for generating complex heterocyclic structures using various catalysts and reagents. His publications indicate a consistent engagement with medicinal chemistry and drug discovery, with an emphasis on creating compounds that target disease mechanisms.
Metrics
- h-index: 15
- Publications: 34
- Citations: 634
Selected Publications
-
Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan (2023)
Collaboration Network
Top Collaborators
B. Rajitha
National Institute of Technology Warangal (IN)
4 shared publications
- I<sub>2</sub>/DMSO-catalyzed one-pot approach for the synthesis of 1,3,4-selenadiazoles
- Design and Synthesis of 11H-Xantheno[2,1-c][1,2,5]Selenadiazol-11-One Derivatives as Potent Antimicrobial and Antitubercular Agents
- Synthesis of 2-(2-oxo-2H-chromen-3-yl)-3-phenylquinazolin-4(3H)-ones as potent antimicrobial and antitubercular agents
- One-pot protocol for the synthesis of quinoxalines from styrenes, o-phenylenediamine and benzo[c][1,2,5]thiadiazole-4,5-diamine using triiodoisocyanuric acid
Marumamula Hanumaiah
Indian Institute of Chemical Technology (IN)
3 shared publications
- Design and Synthesis of 11H-Xantheno[2,1-c][1,2,5]Selenadiazol-11-One Derivatives as Potent Antimicrobial and Antitubercular Agents
- Synthesis of 2-(2-oxo-2H-chromen-3-yl)-3-phenylquinazolin-4(3H)-ones as potent antimicrobial and antitubercular agents
- One-pot protocol for the synthesis of quinoxalines from styrenes, o-phenylenediamine and benzo[c][1,2,5]thiadiazole-4,5-diamine using triiodoisocyanuric acid
Samuel Kakraba
University of Arkansas for Medical Sciences (US)
1 shared publication
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Srinivas Ayyadevara
University of Arkansas for Medical Sciences
1 shared publication
In database
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Nirjal Mainali
University of Arkansas for Medical Sciences
1 shared publication
In database
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Meenakshisundaram Balasubramaniam
University of Arkansas for Medical Sciences
1 shared publication
In database
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Narsimha Reddy Penthala
University of Arkansas for Medical Sciences
1 shared publication
In database
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Ramani Atluri
University of Arkansas for Medical Sciences
1 shared publication
In database
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Steven W. Barger
University of Arkansas for Medical Sciences
1 shared publication
In database
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Sue Griffin
Central Arkansas Veterans Healthcare System (US)
1 shared publication
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Peter A. Crooks
University of Arkansas for Medical Sciences
1 shared publication
In database
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Robert J. Shmookler Reis
Central Arkansas Veterans Healthcare System
1 shared publication
In database
- Thiadiazolidinone (TDZD) Analogs Inhibit Aggregation-Mediated Pathology in Diverse Neurodegeneration Models, and Extend C. elegans Life- and Healthspan
Similar Researchers
Based on overlapping research topics
Amit Raj Sharma
Arkansas State University
Computational Drug Discovery Methods
Synthesis and biological activity
Microbial infections and disease research
Jackeline Rodriguez‐Smith
University of Arkansas for Medical Sciences
Computational Drug Discovery Methods
Microbial infections and disease research
Antimicrobial Resistance in Bacteria
Sujatha Sekar
University of Arkansas for Medical Sciences
Microbial infections and disease research
Neurological disorders and treatments
Disease Mechanisms Research
Hansa Raj K. C.
Arkansas State University
Computational Drug Discovery Methods
Synthesis and biological activity
Antimicrobial Resistance in Bacteria
Ari Filip
University of Arkansas for Medical Sciences
Computational Drug Discovery Methods
Protein Structure and Dynamics
Disease Mechanisms Research
Juarez Braga
University of Arkansas for Medical Sciences
Computational Drug Discovery Methods
Microbial infections and disease research
Disease Mechanisms Research