Match tier
Confirmed
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-05
B
Beverly D. Lyn‐Cook
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
High Impact
Senior Scientist
Also affiliated: University of North Carolina at Chapel Hill (1983–2008); United States Food and Drug Administration (1991–2026); Canisius College (1992); Western University of Health Sciences (2008)
30 h-index
131 pubs
3,206 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Beverly Lyn‐Cook's research focuses on understanding disease mechanisms and health disparities, particularly concerning cancer, metabolism, and the impact of environmental exposures. Her work frequently investigates differences across demographic groups, including sex and race, and utilizes advanced computational methods for data analysis. Lyn‐Cook has published on topics such as the metabolome of breast tissues and its correlation with microbial dysbiosis and lipid metabolism in triple-negative breast tumors, and the association of tryptophan metabolism with obesity and triple-negative breast cancer risk in Black and White women.
Her research also explores the immunotoxicity of nanoparticles, examining sex-based differences in response to agents like silver nanoparticles. Additionally, she has investigated the effects of nanoparticles, such as titanium dioxide, on epigenetic modifications in human cell lines. Lyn‐Cook employs sophisticated data mining and topic modeling techniques, including AI-powered approaches like LDA and BERTopic, to analyze large datasets, such as those related to opioid adverse events and prescription opioid use literature.
Lyn‐Cook is a highly cited researcher with an h-index of 30 and over 130 publications. She leads a research group and has collaborated extensively with colleagues at the National Center for Toxicological Research, including Beverly Word, Paul Rogers, Wen Zou, and Weigong Ge.
Metrics
- h-index: 30
- Publications: 131
- Citations: 3,206
Positions
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Senior Scientist 1988–presentNational Center for Toxicological Research Biochemical Toxicology ORCID
Selected Publications
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Exploring Sex Differences in Cardiac ICU Admission and Length of Stay Using Multiple Correspondence Analysis (2026)
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Exposure to a Titanium Dioxide Product Alters MicroRNA Expression in Human Cells (2026)
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Abstract C054: Pharmacogenomics evaluation of histone deacetylase inhibitors on the treatment of triple-negative breast cancer subtypes (2025)
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AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women (2025)
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Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells (2024)
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Identifying Vulnerabilities to NSAID Adverse Events in the U.S. Population: An Analysis of Preexisting Conditions and Sex (2024)
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Abstract 4253: High expression of specific gene profiles in organoids from African American pancreatic cancer tumors (2024)
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Investigation of sex-based differences in the immunotoxicity of silver nanoparticles (2024)
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RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system (2024)
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A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database (2023)
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Identifying Vulnerabilities to NSAID Adverse Events in the US Population: An Analysis of Pre-Existing Conditions and Sex (2023)
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Epigenotoxicity of Titanium Dioxide Nanoparticles (2023)
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Abstract 6251: High expression level of GSK3β in basal triple negative breast cancer: Effects of the HDAC inhibitor, vorinostat (2023)
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Characterization of the Metabolome of Breast Tissues from Non-Hispanic Black and Non-Hispanic White Women Reveals Correlations between Microbial Dysbiosis and Enhanced Lipid Metabolism Pathways in Triple-Negative Breast Tumors (2022)
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Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines (2022)
Collaboration Network
Top Collaborators
Beverly R. Word
National Center for Toxicological Research
53 shared publications
In database
- Increased expression of Toll-like receptors (TLRs) 7 and 9 and other cytokines in systemic lupus erythematosus (SLE) patients: Ethnic differences and potential new targets for therapeutic drugs
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: Identifying DNA methylation signatures associated with interferon-related genes based on ethnicity and SLEDAI
- Expression of drug transporters in human kidney: impact of sex, age, and ethnicity
- Age and gender affect DNMT3a and DNMT3b expression in human liver
Showing 5 of 53 shared publications
George Hammons
National Center for Toxicological Research
46 shared publications
In database
- Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls
- Chemopreventive Effects of Tea Extracts and Various Components on Human Pancreatic and Prostate Tumor Cells In Vitro
- Increased expression of Toll-like receptors (TLRs) 7 and 9 and other cytokines in systemic lupus erythematosus (SLE) patients: Ethnic differences and potential new targets for therapeutic drugs
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype
Showing 5 of 46 shared publications
Li Pang
15 shared publications
In database
- Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias
- Workshop Report
- Evaluation of Batch Variations in Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes from 2 Major Suppliers
- Sex-Related Differences in Drug-Induced QT Prolongation and Torsades de Pointes: A New Model System with Human iPSC-CMs
- ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?
Showing 5 of 15 shared publications
Athena Starlard‐Davenport
University of Tennessee Health Science Center (US)
13 shared publications
- Distinct microbial communities that differ by race, stage, or breast-tumor subtype in breast tissues of non-Hispanic Black and non-Hispanic White women
- Age and gender affect DNMT3a and DNMT3b expression in human liver
- Identification of UDP-glucuronosyltransferase 1A10 in non-malignant and malignant human breast tissues
- Restoration of the methylation status of hypermethylated gene promoters by microRNA-29b in human breast cancer: A novel epigenetic therapeutic approach
- Food contaminant acrylamide increases expression of Cox-2 and nitric oxide synthase in breast epithelial cells
Showing 5 of 13 shared publications
Stancy J. Joseph
National Center for Toxicological Research (US)
8 shared publications
- Epigenome-wide association study of peripheral blood mononuclear cells in systemic lupus erythematosus: Identifying DNA methylation signatures associated with interferon-related genes based on ethnicity and SLEDAI
- Expression of drug transporters in human kidney: impact of sex, age, and ethnicity
- Abstract 4436: Metformin upregulates hENT1 expression and enhances gemcitabine efficacy in pancreatic cancer cells
- Abstract 4428: Metformin effects on ABCB1 expression and proliferation in pancreatic cancer cell lines with different ABCB1 genotypes/haplotypes
- Abstract 770: Gender differences in the expression of drug metabolizing enzymes in human liver tissues
Showing 5 of 8 shared publications
Lascelles E. Lyn‐Cook
National Center for Toxicological Research
8 shared publications
In database
- Food contaminant acrylamide increases expression of Cox-2 and nitric oxide synthase in breast epithelial cells
- Cigarette Smoke Condensate Induces Differential Expression and Promoter Methylation Profiles of Critical Genes Involved in Lung Cancer in NL-20 Lung Cells In Vitro
- Effect of cigarette smoke condensate on gene promoter methylation in human lung cells
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Cigarette smoke condensate and individual constituents modulate DNA methyltransferase expression in human liver cells
Showing 5 of 8 shared publications
Paul B. Rogers
National Center for Toxicological Research
8 shared publications
In database
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- Investigation of sex-based differences in the immunotoxicity of silver nanoparticles
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Identifying Vulnerabilities to NSAID Adverse Events in the US Population: An Analysis of Pre-Existing Conditions and Sex
Showing 5 of 8 shared publications
Ernice Blann
National Center for Toxicological Research (US)
6 shared publications
- Chemopreventive Effects of Tea Extracts and Various Components on Human Pancreatic and Prostate Tumor Cells In Vitro
- Specific site methylation in the 5′-flanking region of CYP1A2
- Methylation Profile and Amplification of Proto-Oncogenes in Rat Pancreas Induced with Phytoestrogens
- Increased expression of hepatic DNA methyltransferase in smokers
- The effects of phytoestrogens on human pancreatic tumor cells in vitro
Showing 5 of 6 shared publications
Fred F. Kadlubar
National Center for Toxicological Research (US)
6 shared publications
- Human CYP1B1 Leu432Val gene polymorphism: ethnic distribution in African-Americans, Caucasians and Chinese; oestradiol hydroxylase activity; and distribution in prostate cancer cases and controls
- Chemopreventive Effects of Tea Extracts and Various Components on Human Pancreatic and Prostate Tumor Cells In Vitro
- Search for an association between the human CYP1A2 genotype and CYP1A2 metabolic phenotype
- Specific site methylation in the 5′-flanking region of CYP1A2
- Increased expression of hepatic DNA methyltransferase in smokers
Showing 5 of 6 shared publications
Hong‐Gang Wang
National Center for Toxicological Research (US)
6 shared publications
- Cigarette Smoke Condensate Induces Differential Expression and Promoter Methylation Profiles of Critical Genes Involved in Lung Cancer in NL-20 Lung Cells In Vitro
- ATP-Binding Cassette Genes Genotype and Expression: A Potential Association with Pancreatic Cancer Development and Chemoresistance?
- Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol.
- Cytotoxicity of Chronic Exposure to 4 Cigarette Smoke Condensates in 2 Cell Lines
- Abstract A44: Individual variation in hENT expression in normal and malignant pancreatic tissues: The role of dietary agents in enhancing efficacy in gemcitabine treatment.
Showing 5 of 6 shared publications
Norman Stockbridge
Center for Drug Evaluation and Research (US)
6 shared publications
- Comprehensive Translational Assessment of Human-Induced Pluripotent Stem Cell Derived Cardiomyocytes for Evaluating Drug-Induced Arrhythmias
- Workshop Report
- Evaluation of Batch Variations in Induced Pluripotent Stem Cell-Derived Human Cardiomyocytes from 2 Major Suppliers
- Sex-related differences in drug-induced QT prolongation and Torsades de pointes: A new model system with human iPSC-CMs
- Comprehensive assessment of multiple induced pluripotent stem cell-derived cardiomyocyte cell lines with microelectrode arrays and voltage sensitive dyes
Showing 5 of 6 shared publications
Marta Pogribna
National Center for Toxicological Research
6 shared publications
In database
- Effect of titanium dioxide nanoparticles on DNA methylation in multiple human cell lines
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Effect of titanium dioxide nanoparticles on histone modifications and histone modifying enzymes expression in human cell lines
- Epigenotoxicity of Titanium Dioxide Nanoparticles
- Exposure to a Titanium Dioxide Product Alters DNA Methylation in Human Cells
Showing 5 of 6 shared publications
Sulma Ibrahim Mohammed
Purdue University West Lafayette (US)
5 shared publications
- Gender differences in gemcitabine (Gemzar) efficacy in cancer cells: effect of indole-3-carbinol.
- LXR/RXR pathway signaling associated with triple-negative breast cancer in African American women
- Proteomics Profiling of Pancreatic Cancer and Pancreatitis for Biomarkers Discovery
- Abstract 2556: Indole-3-carbinol (I3C) and gemcitabine as potential combinatorial therapy in pancreatic cancer
- Abstract A65: Proteomics of normal, pancreatitis and pancreatic cancer human tissues
Weigong Ge
National Center for Toxicological Research
5 shared publications
In database
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
Huixiao Hong
National Center for Toxicological Research
5 shared publications
In database
- AI-powered topic modeling: comparing LDA and BERTopic in analyzing opioid-related cardiovascular risks in women
- RxNorm for drug name normalization: a case study of prescription opioids in the FDA adverse events reporting system
- A systematic analysis and data mining of opioid-related adverse events submitted to the FAERS database
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
- Text Fingerprinting and Topic Mining in the Prescription Opioid Use Literature
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