Match tier
Listed
Presence
Current · Arkansas
Last published
2020
Sources
OpenAlex · ORCID
Refreshed
2026-10-03
L
Lascelles E. Lyn‐Cook
High Impact
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Also affiliated: University of North Carolina at Chapel Hill (1986–1991); United States Department of Health and Human Services (1996–1997); United States Food and Drug Administration (1991–2017); Brown University (2009); Rhode Island Hospital (2009); United States Public Health Service (1996); Arkansas Children's Research Institute (2020)
21 h-index
58 pubs
1,311 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
Metrics
- h-index: 21
- Publications: 58
- Citations: 1,311
Selected Publications
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Nitrosative Stress and Lipid Homeostasis as a Mechanism for Zileuton Hepatotoxicity and Resistance in Genetically Sensitive Mice (2020)
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Identification of Pharmacogenetic Risk Factors for Zileuton‐Induced Liver Injury Using Diversity Outbred Mice (2017)
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In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation (2017)
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In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver (2016)
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In Vivo Alkaline Comet Assay and Enzyme-modified Alkaline Comet Assay for Measuring DNA Strand Breaks and Oxidative DNA Damage in Rat Liver (2016)
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Idiosyncratic Drug‐Induced Liver Injury Potential of Zileuton is Detected in Diversity Outbred Mice (2015)
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Cigarette smoke condensate and individual constituents modulate DNA methyltransferase expression in human liver cells (2015)
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Cytotoxicity of Chronic Exposure to 4 Cigarette Smoke Condensates in 2 Cell Lines (2015)
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In vivo genotoxicity of estragole in male F 344 rats (2014)
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Effect of cigarette smoke condensate on gene promoter methylation in human lung cells (2014)
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Sex-specific dose-response analysis of genotoxicity in cyproterone acetate-treated F344 rats (2014)
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Abstract 401: Array analysis of cigarette smoke condensate (CSC) on gene promoter methylation in human lung cells (2014)
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Abstract 5376: Expression of histone deacetylases (HDACs) 1, 2, 3 and 7 in pancreatic cancer cell lines: The role of indole-3-carbinol. (2013)
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Genotoxicity of doxorubicin in F344 rats by combining the comet assay, flow‐cytometric peripheral blood micronucleus test, and pathway‐focused gene expression profiling (2013)
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Abstract 3127: Cigarette smoke condensate (CSC) induces differential expression and promoter methylation profiles of critical genes involved in lung cancer in NL-20 lung cells in vitro: Short-term and chronic exposure (2012)
Collaboration Network
Top Collaborators
Anane Aidoo
National Center for Toxicological Research (US)
19 shared publications
- Genotoxicity of acrylamide and its metabolite glycidamide administered in drinking water to male and female Big Blue mice
- Induction of 6‐thioguanine‐resistant lymphocytes in fischer 344 rats following in vivo exposure to n‐ethyl‐n‐nitrosourea and cyclophosphamide
- The effect of time after treatment, treatment schedule and animal age on the frequency of 6-thioguanine-resistant T-lymphocytes induced in Fischer 344 rats by N-ethyl-N-nitrosourea
- Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene of Big Blue® rats treated with 7,12-dimethylbenz[a]anthracene
- Comparison of the types of mutations induced by 7,12-dimethylbenz[a]anthracene in thelacI andhprt genes of Big Blue® rats
Showing 5 of 19 shared publications
Daniel A. Casciano
National Center for Toxicological Research (US)
19 shared publications
- Induction of 6‐thioguanine‐resistant lymphocytes in fischer 344 rats following in vivo exposure to n‐ethyl‐n‐nitrosourea and cyclophosphamide
- Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene of Big Blue® rats treated with 7,12-dimethylbenz[a]anthracene
- Comparison of the types of mutations induced by 7,12-dimethylbenz[a]anthracene in thelacI andhprt genes of Big Blue® rats
- Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue® rats
- Attenuation of bleomycin-induced Hprt mutant frequency in female and male rats by calorie restriction
Showing 5 of 19 shared publications
Mugimane G. Manjanatha
National Center for Toxicological Research
14 shared publications
In database
- Genotoxicity of acrylamide and its metabolite glycidamide administered in drinking water to male and female Big Blue mice
- Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene of Big Blue® rats treated with 7,12-dimethylbenz[a]anthracene
- Comparison of the types of mutations induced by 7,12-dimethylbenz[a]anthracene in thelacI andhprt genes of Big Blue® rats
- DNA sequence analysis of hprt mutations in lymphocytes from Sprague-Dawley rats treated with 7,12-dimethylbenz[a]anthracene
- Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue® rats
Showing 5 of 14 shared publications
James L. Pipkin
National Center for Toxicological Research (US)
12 shared publications
- Chronic caloric restriction induces stress proteins in the hypothalamus of rats
- Dose-response of retinoic acid induced stress protein synthesis and teratogenesis in mice
- The homology of a novel polypeptide with stress protein characteristics in embryonic mice brain and in the hypothalamus of caloric restricted rats as determined by ultramicro western blotting
- p53 synthesis and phosphorylation in the aging diet-restricted rat following retinoic acid administration
- A nuclear protein associated with lethal heat shock of HL-60 cells
Showing 5 of 12 shared publications
William G. Hinson
National Center for Toxicological Research (US)
12 shared publications
- Chronic caloric restriction induces stress proteins in the hypothalamus of rats
- Dose-response of retinoic acid induced stress protein synthesis and teratogenesis in mice
- The homology of a novel polypeptide with stress protein characteristics in embryonic mice brain and in the hypothalamus of caloric restricted rats as determined by ultramicro western blotting
- p53 synthesis and phosphorylation in the aging diet-restricted rat following retinoic acid administration
- A nuclear protein associated with lethal heat shock of HL-60 cells
Showing 5 of 12 shared publications
Ritchie J. Feuers
National Center for Toxicological Research (US)
12 shared publications
- Chronic caloric restriction induces stress proteins in the hypothalamus of rats
- The homology of a novel polypeptide with stress protein characteristics in embryonic mice brain and in the hypothalamus of caloric restricted rats as determined by ultramicro western blotting
- p53 synthesis and phosphorylation in the aging diet-restricted rat following retinoic acid administration
- The temporal relationships of synthesis and phosphorylation in stress proteins 70 and 90 in aged caloric restricted rats exposed to bleomycin
- Modulation of antioxidant enzymes in bleomycin‐treated rats by vitamin c and β‐carotene
Showing 5 of 12 shared publications
Michelle E. Bishop
National Center for Toxicological Research
10 shared publications
In database
- Genotoxicity of acrylamide and its metabolite glycidamide administered in drinking water to male and female Big Blue mice
- Effect of caloric restriction on Hprt lymphocyte mutation in aging rats
- Genotoxicity of doxorubicin in F344 rats by combining the comet assay, flow‐cytometric peripheral blood micronucleus test, and pathway‐focused gene expression profiling
- In vivo antimutagenic activity of beta-carotene in rat spleen lymphocytes
- Influence of dietary antioxidants on the mutagenicity of 7,12-dimethylbenz[a]anthracene and bleomycin in female rats
Showing 5 of 10 shared publications
Beverly Word
National Center for Toxicological Research
9 shared publications
In database
- Food contaminant acrylamide increases expression of Cox-2 and nitric oxide synthase in breast epithelial cells
- Cigarette Smoke Condensate Induces Differential Expression and Promoter Methylation Profiles of Critical Genes Involved in Lung Cancer in NL-20 Lung Cells In Vitro
- Effect of cigarette smoke condensate on gene promoter methylation in human lung cells
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Cigarette smoke condensate and individual constituents modulate DNA methyltransferase expression in human liver cells
Showing 5 of 9 shared publications
George Hammons
National Center for Toxicological Research
9 shared publications
In database
- Food contaminant acrylamide increases expression of Cox-2 and nitric oxide synthase in breast epithelial cells
- Cigarette Smoke Condensate Induces Differential Expression and Promoter Methylation Profiles of Critical Genes Involved in Lung Cancer in NL-20 Lung Cells In Vitro
- Effect of cigarette smoke condensate on gene promoter methylation in human lung cells
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Cigarette smoke condensate and individual constituents modulate DNA methyltransferase expression in human liver cells
Showing 5 of 9 shared publications
Beverly Lyn‐Cook
National Center for Toxicological Research
8 shared publications
In database
- Food contaminant acrylamide increases expression of Cox-2 and nitric oxide synthase in breast epithelial cells
- Cigarette Smoke Condensate Induces Differential Expression and Promoter Methylation Profiles of Critical Genes Involved in Lung Cancer in NL-20 Lung Cells In Vitro
- Effect of cigarette smoke condensate on gene promoter methylation in human lung cells
- In vitro analysis of factors influencingCYP1A2expression as potential determinants of interindividual variation
- Cigarette smoke condensate and individual constituents modulate DNA methyltransferase expression in human liver cells
Showing 5 of 8 shared publications
Robert H. Heflich
National Center for Toxicological Research
7 shared publications
In database
- Induction of 6‐thioguanine‐resistant lymphocytes in fischer 344 rats following in vivo exposure to n‐ethyl‐n‐nitrosourea and cyclophosphamide
- The effect of time after treatment, treatment schedule and animal age on the frequency of 6-thioguanine-resistant T-lymphocytes induced in Fischer 344 rats by N-ethyl-N-nitrosourea
- Comparison of the types of mutations induced by 7,12-dimethylbenz[a]anthracene in thelacI andhprt genes of Big Blue® rats
- Effect of caloric restriction on Hprt lymphocyte mutation in aging rats
- DNA sequence analysis of hprt mutations in lymphocytes from Sprague-Dawley rats treated with 7,12-dimethylbenz[a]anthracene
Showing 5 of 7 shared publications
Ronald W. Hart
National Center for Toxicological Research (US)
6 shared publications
- The homology of a novel polypeptide with stress protein characteristics in embryonic mice brain and in the hypothalamus of caloric restricted rats as determined by ultramicro western blotting
- p53 synthesis and phosphorylation in the aging diet-restricted rat following retinoic acid administration
- The temporal relationships of synthesis and phosphorylation in stress proteins 70 and 90 in aged caloric restricted rats exposed to bleomycin
- P48: A novel nuclear protein possibly associated with aging and mortality
- Histone variants, H1subtypes and other chromatin proteins as biomarkers of age and caloric restriction in rats
Showing 5 of 6 shared publications
Sharon D. Shelton
National Center for Toxicological Research
6 shared publications
In database
- Genotoxicity of acrylamide and its metabolite glycidamide administered in drinking water to male and female Big Blue mice
- Comparison of in vivo mutagenesis in the endogenous Hprt gene and the lacI transgene of Big Blue® rats treated with 7,12-dimethylbenz[a]anthracene
- Comparison of the types of mutations induced by 7,12-dimethylbenz[a]anthracene in thelacI andhprt genes of Big Blue® rats
- Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue® rats
- Dietary effects of soy isoflavones daidzein and genistein on 7,12-dimethylbenz[a]anthracene-induced mammary mutagenesis and carcinogenesis in ovariectomized Big Blue(R) transgenic rats
Showing 5 of 6 shared publications
Roberta A. Mittelstaedt
National Center for Toxicological Research
5 shared publications
In database
- Induction of 6‐thioguanine‐resistant lymphocytes in fischer 344 rats following in vivo exposure to n‐ethyl‐n‐nitrosourea and cyclophosphamide
- Comparison of the types of mutations induced by 7,12-dimethylbenz[a]anthracene in thelacI andhprt genes of Big Blue® rats
- Effect of caloric restriction on Hprt lymphocyte mutation in aging rats
- DNA sequence analysis of hprt mutations in lymphocytes from Sprague-Dawley rats treated with 7,12-dimethylbenz[a]anthracene
- Comparison of mutant frequencies and types of mutations induced by thiotepa in the endogenous Hprt gene and transgenic lacI gene of Big Blue® rats
P. H. Duffy
National Center for Toxicological Research (US)
4 shared publications
- p53 synthesis and phosphorylation in the aging diet-restricted rat following retinoic acid administration
- The temporal relationships of synthesis and phosphorylation in stress proteins 70 and 90 in aged caloric restricted rats exposed to bleomycin
- P48: A novel nuclear protein possibly associated with aging and mortality
- The effect of aging and dietary restriction on the retinoylation of nuclear matrix proteins in rats