Kelly L. Harris Source Confirmed
Affiliation confirmed via AI analysis of OpenAlex, ORCID, and web sources.
Staff Fellow
National Center for Toxicological Research
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Biography and Research Information
OverviewAI-generated summary
Kelly L. Harris's research focuses on the molecular mechanisms underlying carcinogenesis and the assessment of genotoxicity. She has investigated the effects of benzo(a)pyrene, a polycyclic aromatic hydrocarbon, on human colon cancer cells, examining cytotoxicity, DNA damage, and gene expression profiles. Her work also includes the application of CarcSeq technology to measure driver mutations in rat and mouse models of mammary and lung neoplasia, correlating these mutations with spontaneous cancer incidence. Harris has explored the impact of dietary factors, such as the Western diet, on the acceleration of colon carcinogenesis in rat models. Additionally, her research has involved evaluating treatment outcomes for urothelial carcinoma in murine and rat models and assessing the pharmacogenomic effects of histone deacetylase inhibitors on triple-negative breast cancer. She has published 45 papers, accumulating 951 citations, and holds an h-index of 11. Harris collaborates with several researchers at the National Center for Toxicological Research, including Barbara L. Parsons and Binsheng Gong.
Metrics
- h-index: 11
- Publications: 45
- Citations: 951
Selected Publications
- Tissue and Sex‐Specific Performance of a Cancer Driver Based Biomarker in <scp>rasH2</scp> ‐Tg Mice (2025) DOI
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations (2024) DOI
- Assessment of Clonal Expansion Using CarcSeq Measurement of Lung Cancer Driver Mutations and Correlation With Mouse Strain- and Sex-Related Incidence of Spontaneous Lung Neoplasia (2021) DOI
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