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Likely match
Presence
Current · Arkansas
Last published
2022
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
L
Linda S. Von Tungeln
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High Impact
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Also affiliated: Centers for Disease Control and Prevention (2005); National Institutes of Health (2005); United States Food and Drug Administration (1989–2022); Uniformed Services University of the Health Sciences (1993); Georgia State University (1993); Soochow University (1998); Orszagos Kornyezetegeszsegugyi Intezet (2005); National Cancer Institute (2005); National Center for Epidemiology (2005); Instituto Superior Técnico (2003–2005); Centro de Química Estrutural (2003)
25 h-index
79 pubs
2,041 cited
Research Areas
Biomedical Subjects
Biography and Research Information
OverviewAI-generated summary
Linda S. Von Tungeln's research focuses on toxicological evaluations of various substances, utilizing animal models to assess potential health impacts. Her work includes investigating the toxicological effects of brominated vegetable oil in Sprague Dawley rats and examining the impact of urinary pH on the renal toxicity of melamine and cyanuric acid. She has also studied the in vitro effects of cannabidiol and its metabolites on mouse and human Sertoli cells.
Von Tungeln's scholarship metrics include an h-index of 25, with 79 total publications and 2,016 total citations. She is recognized as a high-impact researcher due to her highly cited work. Her collaborative network includes researchers from the National Center for Toxicological Research, such as Frederick A. Beland, Gonçalo Gamboa da Costa, Greg R. Olson, and Si Chen, with whom she has co-authored multiple publications.
Metrics
- h-index: 25
- Publications: 79
- Citations: 2,041
Selected Publications
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Toxicological evaluation of brominated vegetable oil in Sprague Dawley rats (2022)
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In vitro effects of cannabidiol and its main metabolites in mouse and human Sertoli cells (2021)
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Effect of urinary pH upon the renal toxicity of melamine and cyanuric acid (2021)
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In vivo localization and postmortem stability of benzo[a]pyrene‐DNA adducts (2019)
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Comparative pharmacokinetic and biodistribution study of two distinct squalene-containing oil-in-water emulsion adjuvants in H5N1 influenza vaccines (2019)
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Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study (2016)
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Pharmacokinetics and biodistribution of squalene-containing emulsion adjuvant following intramuscular injection of H5N1 influenza vaccine in mice (2016)
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Evaluation of serum and liver toxicokinetics for furan and liver DNA adduct formation in male Fischer 344 rats (2015)
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Pyrrolizidine Alkaloid-Derived DNA Adducts as a Common Biological Biomarker of Pyrrolizidine Alkaloid-Induced Tumorigenicity (2013)
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Urinary Biomarker Detection of Melamine- and Cyanuric Acid-Induced Kidney Injury in Rats (2012)
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Pharmacokinetics of Melamine and Cyanuric Acid and Their Combinations in F344 Rats (2012)
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Dose–response assessment of nephrotoxicity from a twenty-eight-day combined-exposure to melamine and cyanuric acid in F344 rats (2012)
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Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay (2012)
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Benzocaine-induced methemoglobinemia in an acute-exposure rat model (2011)
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Dose-Response Assessment of Nephrotoxicity from a 7-Day Combined Exposure to Melamine and Cyanuric Acid in F344 Rats (2010)
Collaboration Network
Top Collaborators
Peter P. Fu
National Center for Toxicological Research (US)
48 shared publications
- High-Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry for the Detection and Quantitation of Benzo[a]pyrene−DNA Adducts
- Pyrrolizidine Alkaloid-Derived DNA Adducts as a Common Biological Biomarker of Pyrrolizidine Alkaloid-Induced Tumorigenicity
- Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse
- Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl–DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation
- Neonatal Mouse Assay for Tumorigenicity: Alternative to the Chronic Rodent Bioassay
Showing 5 of 48 shared publications
Frederick A. Beland
National Center for Toxicological Research
23 shared publications
In database
- DNA Adduct Formation from Acrylamide via Conversion To Glycidamide in Adult and Neonatal Mice
- High-Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry for the Detection and Quantitation of Benzo[a]pyrene−DNA Adducts
- Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay
- Dose-Response Assessment of Nephrotoxicity from a 7-Day Combined Exposure to Melamine and Cyanuric Acid in F344 Rats
- Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study
Showing 5 of 23 shared publications
Robert H. Heflich
National Center for Toxicological Research
17 shared publications
In database
- DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide
- Effect of the nitro group conformation on the rat liver microsomal metabolism and bacterial mutagenicity of 2- and 9-nitroanthracene
- Levels of 4‐aminobiphenyl‐induced somatic H‐ras mutation in mouse liver DNA correlate with potential for liver tumor development
- Transplacental drug transfer and frequency of Tk and Hprt lymphocyte mutants and peripheral blood micronuclei in mice treated transplacentally with zidovudine and lamivudine
- Liver tumors induced in B6C3F1 mice by 7-chlorobenz[a]anthracene and 7-bromobenz[a]anthracene contain K-ras protooncogene mutations
Showing 5 of 17 shared publications
Gonçalo Gamboa da Costa
National Center for Toxicological Research
11 shared publications
In database
- DNA Adduct Formation from Acrylamide via Conversion To Glycidamide in Adult and Neonatal Mice
- Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay
- Dose-Response Assessment of Nephrotoxicity from a 7-Day Combined Exposure to Melamine and Cyanuric Acid in F344 Rats
- DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide
- Dose–response assessment of nephrotoxicity from a twenty-eight-day combined-exposure to melamine and cyanuric acid in F344 rats
Showing 5 of 11 shared publications
Daniel R. Doerge
National Center for Toxicological Research
10 shared publications
In database
- DNA Adduct Formation from Acrylamide via Conversion To Glycidamide in Adult and Neonatal Mice
- High-Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry for the Detection and Quantitation of Benzo[a]pyrene−DNA Adducts
- Pyrrolizidine Alkaloid-Derived DNA Adducts as a Common Biological Biomarker of Pyrrolizidine Alkaloid-Induced Tumorigenicity
- Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay
- Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study
Showing 5 of 10 shared publications
Diógenes Herreno-Sáenz
University of Puerto Rico, Medical Sciences Campus (PR)
9 shared publications
- DNA adducts and carcinogenicity of nitro-polycyclic aromatic hydrocarbons.
- Characterization of DNA adducts in Chinese hamster ovary cells treated with mutagenic doses of 1- and 3-nitrosobenzo[a]pyrene and the trans-7,8-diol-anti-9,10-epoxides of 1- and 3-nitrobenzo[a]pyrene
- Tumorigenicity of nitropolycyclic aromatic hydrocarbons in the neonatal B6C3F1 mouse bioassay and characterization of ras mutations in liver tumors from treated mice
- Separation of 32P-labeled 3′,5′-bisphosphate nucleotides of polycyclic aromatic hydrocarbon anti-diol-epoxides and derivatives
- DNA Adducts and Carcinogenicity of Nitro-polycyclic Aromatic Hydrocarbons
Showing 5 of 9 shared publications
Qingsu Xia
National Center for Toxicological Research
8 shared publications
In database
- Pyrrolizidine Alkaloid-Derived DNA Adducts as a Common Biological Biomarker of Pyrrolizidine Alkaloid-Induced Tumorigenicity
- Liver tumors induced in B6C3F1 mice by 7-chlorobenz[a]anthracene and 7-bromobenz[a]anthracene contain K-ras protooncogene mutations
- Neonatal Mouse Tumorigenicity Bioassay
- Tumorigenicity of nitropolycyclic aromatic hydrocarbons in the neonatal B6C3F1 mouse bioassay and characterization of ras mutations in liver tumors from treated mice
- Tumorigenicity and liver tumor ras-protooncogene mutations in CD-1 mice treated neonatally with 1- and 3-nitrobenzo[a]pyrene and their trans-7,8-dihydrodiol and aminobenzo[a]pyrene metabolites
Showing 5 of 8 shared publications
Thomas J. Bucci
National Center for Toxicological Research (US)
8 shared publications
- Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse
- Caloric restriction profoundly inhibits liver tumor formation after initiation by 6-nitrochrysene in male mice
- Potent tumorigenicity of 7-chlorobenz[α]anthracene and 7-bromobenz[α]anthracene in the neonatal B6C3F1 male mouse
- Structure, Tumorigenicity, Microsomal Metabolism, and DNA Binding of 7-Nitrodibenz[ a,h ]anthracene
- Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F1 neonatal mouse
Showing 5 of 8 shared publications
Ronald W. Hart
National Center for Toxicological Research (US)
8 shared publications
- Caloric restriction profoundly inhibits liver tumor formation after initiation by 6-nitrochrysene in male mice
- Liver tumors induced in B6C3F1 mice by 7-chlorobenz[a]anthracene and 7-bromobenz[a]anthracene contain K-ras protooncogene mutations
- Inhibitory effect of caloric restriction on tumorigenicity induced by 4-aminobiphenyl and 2-amino-1-methyl-6-phenylimidazo-[4,5-b]pyridine (PhIP) in the CD1 newborn mouse bioassay
- Effect of caloric restriction on the metabolism of 7-bromobenz[a]anthracene and 7-fluorobenz[a]anthracene by male B6C3F1 mouse liver microsomes: Reduction of metabolic activation pathway
- DNA Adducts and Carcinogenicity of Nitro-polycyclic Aromatic Hydrocarbons
Showing 5 of 8 shared publications
Fred F. Kadlubar
National Center for Toxicological Research (US)
8 shared publications
- Comparative carcinogenicity of 4-aminobiphenyl and the food pyrolysates, Glu-P-1, IQ, PhIP, and MeIQx in the neonatal B6C3F1 male mouse
- Immunochemical, 32P-postlabeling, and GC/MS detection of 4-aminobiphenyl–DNA adducts in human peripheral lung in relation to metabolic activation pathways involving pulmonary N-oxidation, conjugation, and peroxidation
- Neonatal Mouse Assay for Tumorigenicity: Alternative to the Chronic Rodent Bioassay
- Caloric restriction profoundly inhibits liver tumor formation after initiation by 6-nitrochrysene in male mice
- Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F1 neonatal mouse
Showing 5 of 8 shared publications
Mona I. Churchwell
National Center for Toxicological Research
6 shared publications
In database
- DNA Adduct Formation from Acrylamide via Conversion To Glycidamide in Adult and Neonatal Mice
- High-Performance Liquid Chromatography Electrospray Ionization Tandem Mass Spectrometry for the Detection and Quantitation of Benzo[a]pyrene−DNA Adducts
- DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide
- Evaluation of serum and liver toxicokinetics for furan and liver DNA adduct formation in male Fischer 344 rats
- In vivo localization and postmortem stability of benzo[a]pyrene‐DNA adducts
Showing 5 of 6 shared publications
Ming W. Chou
National Center for Toxicological Research (US)
6 shared publications
- Induction of rat hepatic cytochromes P-450 by environmental nitropolycyclic aromatic hydrocarbons
- Metabolism of 9-nitroanthracene by rat liver microsomes: identification and mutagenicity of metabolites
- Tumorigenicity of chloral hydrate, trichloroacetic acid, trichloroethanol, malondialdehyde, 4-hydroxy-2-nonenal, crotonaldehyde, and acrolein in the B6C3F1 neonatal mouse
- Effect of caloric restriction on the metabolism of 7-bromobenz[a]anthracene and 7-fluorobenz[a]anthracene by male B6C3F1 mouse liver microsomes: Reduction of metabolic activation pathway
- Effect of caloric restriction on the stereoselective metabolism of 7-chlorobenz[a]anthracene by male B6C3F1 mouse liver microsomes
Showing 5 of 6 shared publications
Cristina C. Jacob
National Center for Toxicological Research (US)
6 shared publications
- Dose-Response Assessment of Nephrotoxicity from a 7-Day Combined Exposure to Melamine and Cyanuric Acid in F344 Rats
- Dose–response assessment of nephrotoxicity from a twenty-eight-day combined-exposure to melamine and cyanuric acid in F344 rats
- Pharmacokinetics of Melamine and Cyanuric Acid and Their Combinations in F344 Rats
- Urinary Biomarker Detection of Melamine- and Cyanuric Acid-Induced Kidney Injury in Rats
- Toxicological evaluation of brominated vegetable oil in Sprague Dawley rats
Showing 5 of 6 shared publications
Li‐Hsueh Chiu
National Center for Toxicological Research (US)
5 shared publications
- Halogenated‐polycyclic aromatic hydrocarbons: A class of Genotoxic environmental pollutants
- Structure, Tumorigenicity, Microsomal Metabolism, and DNA Binding of 7-Nitrodibenz[ a,h ]anthracene
- Characterization of DNA adducts in Chinese hamster ovary cells treated with mutagenic doses of 1- and 3-nitrosobenzo[a]pyrene and the trans-7,8-diol-anti-9,10-epoxides of 1- and 3-nitrobenzo[a]pyrene
- Separation of 32P-labeled 3′,5′-bisphosphate nucleotides of polycyclic aromatic hydrocarbon anti-diol-epoxides and derivatives
- Microsomal Metabolism of 7-Nitrodibenz[a,h]anthracene: Effect of the Nitro Substituent on Regioselective Oxidative Metabolism
M. Matilde Marques
National Center for Toxicological Research (US)
5 shared publications
- DNA Adduct Formation from Acrylamide via Conversion To Glycidamide in Adult and Neonatal Mice
- Tumorigenicity of acrylamide and its metabolite glycidamide in the neonatal mouse bioassay
- Low dose assessment of the carcinogenicity of furan in male F344/N Nctr rats in a 2-year gavage study
- DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide
- DNA adduct formation and induction of micronuclei and mutations in B6C3F1/Tk mice treated neonatally with acrylamide or glycidamide
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