Mason McCrury

Researcher

UAMS

Last publication 2026 Last refreshed 2026-05-16

faculty

3 h-index 59 pubs 27 cited

Research Areas

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OverviewAI-generated summary

Mason McCrury's research focuses on cancer-related molecular mechanisms, particularly investigating therapeutic targets and regulators of oncogenic pathways in lymphomas and non-small cell lung carcinoma. His work has explored the role of NEK2 as a therapeutic target in lymphoma and has investigated novel approaches to target oncogenes, such as using small molecules to inhibit G-quadruplex structures in the CARD11 oncogene promoter. McCrury has also contributed to understanding DNA structures, including G-quadruplex and i-motif formations in the promoter of the MYD88 gene, and the function of Rev1 in disrupting G-quadruplexes and stimulating translesion DNA synthesis. His publications include studies on bifunctional inhibitors and the conservation of protein motifs involved in DNA synthesis and repair. McCrury has a significant publication record with 59 total publications and a h-index of 3, with considerable collaboration with researchers at the University of Arkansas for Medical Sciences, including Kennith Swafford, Vijay Patel, Ying-Zhi Xu, and Sydnye L. Shuttleworth.

Metrics

h-index: 3
Publications: 59
Citations: 27

Selected Publications

G-quadruplex and i-motif DNA structures form in the promoter of the key innate immune adaptor MYD88 (2025)

5 citations DOI OpenAlex
Bifunctional Inhibitor Reveals NEK2 as a Therapeutic Target and Regulator of Oncogenic Pathways in Lymphoma (2023)

13 citations DOI OpenAlex
Conservation of the insert-2 motif confers Rev1 from different species with an ability to disrupt G-quadruplexes and stimulate translesion DNA synthesis (2023)

2 citations DOI OpenAlex
Targeting a Novel G-Quadruplex in the CARD11 Oncogene Promoter with Naptho(2,1-b)furan-1-ethanol,2-nitro- Requires the Nitro Group (2022)

6 citations DOI OpenAlex