Biography and Research Information
OverviewAI-generated summary
Anne K. Bowlin's research centers on host-pathogen interactions and the physiological adaptations of animal models to various conditions. Her work investigates how infections, such as those caused by Leishmania major, impact host cellular processes. For instance, her publications explore the role of hypoxia-inducible factor signaling in macrophages during Leishmania major infection, examining its influence on macrophage function and lymphangiogenesis. She has also studied transcriptional remodeling in macrophages in response to leishmanial lesions and inflammatory environments.
Beyond infectious disease models, Bowlin's research extends to comparative nutritional studies using animal models. She has investigated the differences in the small intestine and circulatory metabolome profiles of piglets fed human milk versus milk formula. Additionally, her work includes analyzing the bacterial and fungal adaptations in the digestive tracts of piglets under different milk diets, comparing dairy-based milk formula to human milk. These studies contribute to understanding dietary impacts on host-microbial communities and host physiology.
Bowlin's scholarly output includes 74 publications with 1,304 citations, and she holds an h-index of 23. She has collaborated with researchers such as Hayden Roys, Lucy Fry, and G. Venugopal, all from the University of Arkansas for Medical Sciences, on numerous shared publications.
Metrics
- h-index: 23
- Publications: 74
- Citations: 1,320
Selected Publications
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Guanylate-binding proteins balance iNOS/Arg-1 in myeloid cells during <i>L. major</i> infection and promote host defense to infection (2026)
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Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267 (2025)
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Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells (2025)
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Dysregulated lymphatic remodeling promotes immunopathology during non-healing cutaneous leishmaniasis (2025)
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Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis (2025)
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HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection (2025)
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HIF-α signaling regulates the macrophage inflammatory response during <i>Leishmania major</i> infection (2024)
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Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs (2024)
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Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis (2024)
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Distinct lymphatic remodeling is associated with healing and non-healing murine cutaneous leishmaniasis (2023)
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In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution (2022)
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Erratum for Weinkopff et al., “ <i>Leishmania</i> Infection Induces Macrophage Vascular Endothelial Growth Factor A Production in an ARNT/HIF-Dependent Manner” (2022)
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Bacterial and Fungal Adaptations in Cecum and Distal Colon of Piglets Fed With Dairy-Based Milk Formula in Comparison With Human Milk (2022)
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HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection (2021)
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Milk Formula Diet Alters Bacterial and Host Protein Profile in Comparison to Human Milk Diet in Neonatal Piglet Model (2021)
Collaboration Network
Top Collaborators
Hayden Roys
University of Arkansas for Medical Sciences
19 shared publications
In database
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
Showing 5 of 19 shared publications
Tiffany Weinkopff
University of Arkansas for Medical Sciences
18 shared publications
In database
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
Showing 5 of 18 shared publications
Lucy Fry
University of Arkansas for Medical Sciences
15 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 15 shared publications
Gopinath Venugopal
University of Arkansas for Medical Sciences (US)
11 shared publications
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
Showing 5 of 11 shared publications
Jordan T. Bird
University of Arkansas for Medical Sciences (US)
11 shared publications
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 11 shared publications
Stephanie D. Byrum
Arkansas Children's Hospital
10 shared publications
In database
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- Milk Formula Diet Alters Bacterial and Host Protein Profile in Comparison to Human Milk Diet in Neonatal Piglet Model
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- Both the Infection Status and Inflammatory Microenvironment Induce Transcriptional Remodeling in Macrophages in Murine Leishmanial Lesions
Showing 5 of 10 shared publications
Charity L. Washam
University of Arkansas for Medical Sciences
9 shared publications
In database
- In vivo transcriptional analysis of mice infected with Leishmania major unveils cellular heterogeneity and altered transcriptomic profiling at single-cell resolution
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
- In vivo reprogramming of murine host immune response genes following Leishmania major infection
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection
Showing 5 of 9 shared publications
Alexx Weaver
University of Arkansas for Medical Sciences
4 shared publications
In database
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis
- Enhanced Translational Activity Is Linked to Lymphatic Endothelial Cell Activation in Cutaneous Leishmaniasis
- Synthesis and in vitro evaluation shows disquaramide compounds are a promising class of anti-leishmanial drugs
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267
Fernanda Rosa
United States Department of Agriculture (US)
3 shared publications
- Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets
- Bacterial and Fungal Adaptations in Cecum and Distal Colon of Piglets Fed With Dairy-Based Milk Formula in Comparison With Human Milk
- Milk Formula Diet Alters Bacterial and Host Protein Profile in Comparison to Human Milk Diet in Neonatal Piglet Model
Laxmi Yeruva
Agricultural Research Service (US)
3 shared publications
- Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets
- Bacterial and Fungal Adaptations in Cecum and Distal Colon of Piglets Fed With Dairy-Based Milk Formula in Comparison With Human Milk
- Milk Formula Diet Alters Bacterial and Host Protein Profile in Comparison to Human Milk Diet in Neonatal Piglet Model
Humphrey Wanjala
University of Arkansas for Medical Sciences
3 shared publications
In database
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
Manjunath Bettadapura
University of Arkansas for Medical Sciences
3 shared publications
In database
- Hypoxia-Inducible Factor Signaling in Macrophages Promotes Lymphangiogenesis in Leishmania major Infection
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
Stephanie D. Byrum
3 shared publications
- Guanylate-Binding Proteins Promote Host Defense Against <i>Leishmania major</i> by Balancing iNOS/Arg-1 in Myeloid Cells
- Enhanced translational activity is linked to lymphatic endothelial cell activation in cutaneous leishmaniasis 4267
- HIF-α signaling regulates the macrophage inflammatory response during Leishmania major infection 4332
Ahmed A. Elolimy
Agricultural Research Service (US)
2 shared publications
- Human Milk-Fed Piglets Have a Distinct Small Intestine and Circulatory Metabolome Profile Relative to That of Milk Formula-Fed Piglets
- Bacterial and Fungal Adaptations in Cecum and Distal Colon of Piglets Fed With Dairy-Based Milk Formula in Comparison With Human Milk
Steven Murdock
University of Arkansas for Medical Sciences
2 shared publications
In database
- HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection
- HIF-alpha Activation Impacts Macrophage Function During Murine <em>Leishmania major</em> Infection
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