Frederick F. Lang

Federal Grant PI

Researcher

Last publication 2026 Last refreshed 2026-05-22

faculty

6 h-index 15 pubs 1,057 cited

Biography and Research Information

OverviewAI-generated summary

Frederick F. Lang's research program focuses on neuro-oncology and related areas within cancer treatment. He has investigated the efficacy of middle meningeal artery embolization as a treatment for chronic subdural hematoma in oncological patients, comparing it with surgical drainage. His work also explores the impact of oncogenic drivers on the tumor microenvironment in human gliomas and the role of immunotherapy in non-small cell lung cancer (NSCLC) patients with brain metastases, particularly in conjunction with immune checkpoint inhibitors.

Lang is the PI on a $76,500 NIH/National Cancer Institute grant for the "Development of immunocompetent melanoma brain metastases organoids." His publications include studies on the introduction to surgical management of infiltrative gliomas, molecular and clinical determinants of response to immunotherapy in high-grade glioma, and the use of oncolytic DNX-2401 virotherapy combined with pembrolizumab in recurrent glioblastoma.

His scholarship metrics include an h-index of 6, with 15 total publications and 1,057 total citations. Lang collaborates with other researchers at the University of Arkansas for Medical Sciences, including William J. Shelton and A. Mathews, and maintains an active lab website.

Metrics

  • h-index: 6
  • Publications: 15
  • Citations: 1,057

Selected Publications

  • Impact of baseline brain metastases on survival and CNS progression in NSCLC patients treated with immune checkpoint inhibitors in real-world studies: a systematic review and meta-analysis (2026)

View all publications on OpenAlex →

Federal Grants 1 $76,500 total

NIH/National Cancer Institute Contact PI Mar 2024 - Feb 2026

Development of immunocompetent melanoma brain metastases organoids

National Cancer Institute $76,500 R03

Collaboration Network

76 Collaborators 15 Institutions 2 Countries

Top Collaborators

Similar Researchers

Based on overlapping research topics