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OverviewAI-generated summary
Frederick F. Lang's research program focuses on neuro-oncology and related areas within cancer treatment. He has investigated the efficacy of middle meningeal artery embolization as a treatment for chronic subdural hematoma in oncological patients, comparing it with surgical drainage. His work also explores the impact of oncogenic drivers on the tumor microenvironment in human gliomas and the role of immunotherapy in non-small cell lung cancer (NSCLC) patients with brain metastases, particularly in conjunction with immune checkpoint inhibitors.
Lang is the PI on a $76,500 NIH/National Cancer Institute grant for the "Development of immunocompetent melanoma brain metastases organoids." His publications include studies on the introduction to surgical management of infiltrative gliomas, molecular and clinical determinants of response to immunotherapy in high-grade glioma, and the use of oncolytic DNX-2401 virotherapy combined with pembrolizumab in recurrent glioblastoma.
His scholarship metrics include an h-index of 6, with 15 total publications and 1,057 total citations. Lang collaborates with other researchers at the University of Arkansas for Medical Sciences, including William J. Shelton and A. Mathews, and maintains an active lab website.
Metrics
- h-index: 6
- Publications: 15
- Citations: 1,057
Selected Publications
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Impact of baseline brain metastases on survival and CNS progression in NSCLC patients treated with immune checkpoint inhibitors in real-world studies: a systematic review and meta-analysis (2026)
Federal Grants 1 $76,500 total
Development of immunocompetent melanoma brain metastases organoids
Collaboration Network
Top Collaborators
- Oncogenic drivers shape the tumor microenvironment in human gliomas
- Chronic subdural hematoma treatment in oncological patients: middle meningeal artery embolization versus surgical drainage
- 2082 Middle Meningeal Artery Embolization in 108 Chronic Subdural Hematoma in Thrombocytopenic Cancer Patients
- Introduction. Surgical management of infiltrative gliomas
- Oncogenic drivers shape the tumor microenvironment in human gliomas
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Chronic subdural hematoma treatment in oncological patients: middle meningeal artery embolization versus surgical drainage
- 2082 Middle Meningeal Artery Embolization in 108 Chronic Subdural Hematoma in Thrombocytopenic Cancer Patients
- Chronic subdural hematoma treatment in oncological patients: middle meningeal artery embolization versus surgical drainage
- 2082 Middle Meningeal Artery Embolization in 108 Chronic Subdural Hematoma in Thrombocytopenic Cancer Patients
- Chronic subdural hematoma treatment in oncological patients: middle meningeal artery embolization versus surgical drainage
- 2082 Middle Meningeal Artery Embolization in 108 Chronic Subdural Hematoma in Thrombocytopenic Cancer Patients
- Chronic subdural hematoma treatment in oncological patients: middle meningeal artery embolization versus surgical drainage
- Introduction. Surgical management of infiltrative gliomas
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
- Author Correction: Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial
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