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Presence Current · Arkansas
Last published 2026
Sources OpenAlex · ORCID
Refreshed 2026-10-08

Steven J. Murdock

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Also affiliated: Virginia Commonwealth University (2020)

4 h-index 8 pubs 73 cited

  • Animals
  • Mice
  • Virus Latency
  • Cell Differentiation
  • Female
  • Humans
  • B-Lymphocytes
  • Herpesviridae Infections
  • Mice, Inbred C57BL
  • Tumor Suppressor Protein p53
  • Germinal Center
  • Cell Proliferation
  • Antigens, Viral
  • Nuclear Proteins
  • Virus Replication

Biography and Research Information

OverviewAI-generated summary

Steven J. Murdock's research focuses on understanding the molecular mechanisms of viral infections and the host immune response. He has investigated the role of tumor suppressor protein p53 in restricting gammaherpesvirus-driven germinal center B cell expansion during latency establishment. Murdock also studies how HIF-α activation impacts macrophage function during murine Leishmania major infection, exploring the molecular underpinnings of these interactions. His work also delves into the mechanisms of KSHV latency establishment and maintenance, as well as the potential implications of KSHV LANA in immune evasion by repressing productive viral replication and reducing adaptive immune activation. Murdock has published on topics including regulatory T cells and breast cancer progression, and the functional reprogramming of myeloid cells. His scholarship metrics include an h-index of 4 with 72 total citations across 9 publications. He has collaborated with several researchers at the University of Arkansas for Medical Sciences, including J. Craig Forrest and Mark Manzano.

Metrics

  • h-index: 4
  • Publications: 8
  • Citations: 73

Selected Publications

  • Repression of productive viral replication by KSHV LANA correlates with reduced adaptive immune activation: potential implications for KSHV immune evasion (2026)
    mBio DOI OpenAlex
  • The amplitude of gammaherpesvirus lytic replication dictates adaptive immune activation: Potential implications for KSHV LANA in immune evasion (2026)
    bioRxiv (Cold Spring Harbor Laboratory) 1 citation DOI OpenAlex
  • Intrinsic p53 activation restricts gammaherpesvirus driven germinal center B cell expansion during latency establishment (2025)
    Nature Communications 4 citations DOI OpenAlex
  • Molecular Mechanisms of KSHV Latency Establishment and Maintenance (2024)
    Current Clinical Microbiology Reports 4 citations DOI OpenAlex
  • HIF-α Activation Impacts Macrophage Function during Murine Leishmania major Infection (2021)
    Pathogens 10 citations DOI OpenAlex
  • HIF-alpha Activation Impacts Macrophage Function During Murine Leishmania major Infection (2021)
    Preprints.org 2 citations DOI OpenAlex

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Collaboration Network

22 Collaborators 4 Institutions 1 Country

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