Joseph J. Goellner profile photo

Joseph J. Goellner

Research Instructor

University of Arkansas for Medical Sciences

faculty

Internal Med, College of Medicine

19 h-index 29 pubs 3,976 cited

Research Areas

Bone Metabolism and Diseases Pharmacological Effects and Toxicity Studies Orthopedic Surgery and Rehabilitation Immune Response and Inflammation Bone health and treatments

Links

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OverviewAI-generated summary

Joseph J. Goellner studies bone remodeling and the effects of pharmacological agents on bone metabolism. His research investigates the role of osteoprotegerin (OPG) in regulating bone resorption, particularly in the context of osteocyte and osteoblast function. Dr. Goellner's work explores how therapies like denosumab and romosozumab influence bone remodeling processes, including rebound resorption following treatment discontinuation and the potential for anabolic responses during therapy. He has published 29 papers and has a citation count of 3,976, with an h-index of 19. His recent publications focus on the mechanisms by which local OPG production affects bone resorption and the impact of potent bone remodeling suppression on anabolic responses in mouse models. Dr. Goellner collaborates with researchers at the University of Arkansas for Medical Sciences, including Charles A. O’Brien and Jeff D. Thostenson.

Metrics

  • h-index: 19
  • Publications: 29
  • Citations: 3,976

Selected Publications

  • Potent suppression of bone remodeling by denosumab does not blunt the anabolic response to romosozumab in mice (2025) DOI
  • Reduced osteoprotegerin expression by osteocytes may contribute to rebound resorption after denosumab discontinuation (2023) DOI

Grants & Funding

  • Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Co-Investigator
  • Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator

Collaborators

Researchers in the database who share publications

Charles A. O’Brien University of Arkansas for Medical Sciences 3 shared publications Jeff D. Thostenson University of Arkansas for Medical Sciences 3 shared publications Humberto Reyes-Pardo University of Arkansas for Medical Sciences 2 shared publications Michela Palmieri University of Arkansas for Medical Sciences 2 shared publications Intawat Nookaew University of Arkansas for Medical Sciences 1 shared publication Elena Ambrogini University of Arkansas for Medical Sciences 1 shared publication C. Lowry Barnes University of Arkansas for Medical Sciences 1 shared publication Diana Escalona‐Vargas University of Arkansas for Medical Sciences 1 shared publication

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