Shuoqiu Deng
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Also affiliated: Nanjing University of Chinese Medicine (2019); University of Arkansas Medical Center (2025); China Academy of Chinese Medical Sciences (2020–2026); Institute of Chinese Materia Medica (2020–2026); Arkansas Children's Research Institute (2026); Jiangsu Key Laboratory for Pharmacology and Safety Evaluation of Chinese Materia Medica (2019)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Shuoqiu Deng's research focuses on understanding the mechanisms of various diseases and exploring potential therapeutic interventions. Deng has investigated the protective effects of natural compounds and herbal formulas against myocardial injury induced by particulate matter exposure and ischemia, often examining the underlying molecular pathways such as PI3K/AKT/p38 MAPK/Nrf2 and NLRP3 inflammasomes. This work includes studies on Shengmai Formula and Shenlian extract. Additionally, Deng's research extends to experimental cerebral malaria, exploring the effects of artesunate and tetramethylpyrazine on mechanisms like protein S-nitrosylation and the regulation of PDGFRβ signaling. Deng has also explored the role of microRNAs, such as microRNA-32-5b, in cancer metastasis and drug sensitivity. Collaborations include work with Christoph Mora, Yunmeng Liu, Katherine Deck, and Pamela I. Rogers at the University of Arkansas for Medical Sciences.
Metrics
- h-index: 5
- Publications: 34
- Citations: 102
Selected Publications
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Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031 (2026)
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Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853 (2026)
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Acellular normothermic spleen perfusion resolves transcriptional and non-transcriptional mechanisms of steroid immunosuppression (2026)
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Kidney Resident Memory CD8+ T cells drive the immortality of hypertension (2026)
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Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension (2026)
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IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287 (2025)
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P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289 (2025)
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Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288 (2025)
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Energy Overload: ATP-P2X7-Mediated T Cell Activation in Obesity-Induced Type 2 Diabetes 9286 (2025)
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Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension (2025)
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Uncovering immune pathways for therapeutic targeting of hypertension (2025)
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Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications (2025)
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Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction (2025)
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Establishment of resident memory T cells anchors hypertension in the kidney (2025)
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SS-31 Attenuates Doxorubicin-induced Cardiomyoblast H9C2 Cell Senescence (2024)
Collaboration Network
Top Collaborators
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
Showing 5 of 13 shared publications
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- SS-31 Attenuates Doxorubicin-induced Cardiomyoblast H9C2 Cell Senescence
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
Showing 5 of 10 shared publications
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
Showing 5 of 9 shared publications
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
Showing 5 of 9 shared publications
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
- Energy Overload: ATP-P2X7-Mediated T Cell Activation in Obesity-Induced Type 2 Diabetes 9286
- Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288
- IL-10 Drives Macrophage to Myofibroblast Transition Promoting Chronic Fibrosis in the Failing Heart 9287
Showing 5 of 9 shared publications
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
- Cytokine-induced Macrophage Transition Drives Cardiac Fibrosis and Diastolic Dysfunction
- Kidney resident-memory CD8+ T cells drive chronic high blood pressure 9288
Showing 5 of 6 shared publications
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Establishment of resident memory T cells anchors hypertension in the kidney
- P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
- Kidney Resident Memory CD8+ T cells drive the immortality of hypertension
- Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853
- Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
- Kidney Resident Memory CD8+ T cells drive the immortality of hypertension
- Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853
- Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
- Kidney Resident Memory CD8+ T cells drive the immortality of hypertension
- Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853
- Macrophage Plasticity Drives Cardiac Dysfunction in Hypertension 2253031
- Kidney Memory for Salt Sensitivity Resides in T Cells Driving Chronic Hypertension
- Energy Overload: ATP-P2X7-Mediated T Cell Activation in Obesity-Induced Type 2 Diabetes 9286
- P2X7 Drives T-cell Activation Promoting Chronic Inflammation During High Blood Pressure 9289
- Immune Dysregulation Connecting Type 2 Diabetes and Cardiovascular Complications
- Uncovering immune pathways for therapeutic targeting of hypertension
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
- Kidney Resident Memory CD8+ T cells drive the immortality of hypertension
- Cytokine-mediated macrophage transition promotes early cardiac fibrosis in chronic hypertension
- Kidney Resident Memory CD8+ T cells drive the immortality of hypertension
- Kidney Resident Memory CD8+ T cells drive the immortality of hypertension
- Antigen-independent formation of renal Trm-like CD8 T cells perpetuates hypertension 2259853
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