Visanu Wanchai
Instructor
faculty
Biomedical Informatics, College of Medicine
Research Areas
Biography and Research Information
OverviewAI-generated summary
Visanu Wanchai's research interests include the genomic analysis of various organisms and the study of disease mechanisms. His work has involved investigating the genetic makeup of bacteria, such as Escherichia coli, and identifying distinct phylogroups. Wanchai has also contributed to understanding viral genomes, examining the genetic repertoire of SARS-CoV-2 during different pandemic waves and comparing Monkeypox virus genomes from distinct outbreaks.
Furthermore, his research extends to cancer biology, with studies focusing on multiple myeloma. This includes investigating immune microenvironment alterations in multiple myeloma and its precursor stages, as well as exploring the efficacy of bispecific CAR-T cells in controlling myeloma growth. Wanchai's work also touches upon cellular biology, including the refinement of mesenchymal cell types associated with murine bone structures and transcriptomic analysis using native RNA or cDNA sequencing.
Metrics
- h-index: 15
- Publications: 49
- Citations: 966
Selected Publications
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An Enhancement of Extrachromosomal Circular DNA Enrichment and Amplification to Address the Extremely Low Overlap Between Replicates (2026)
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Elevation of master autophagy regulator Tfeb in osteoblast lineage cells increases bone mass and strength (2025)
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An Enhancement of Extrachromosomal Circular DNA Enrichment and Amplification to Address the Extremely Low Overlap Between Replicates (2025)
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Single Nuclei Multiomic Profiling of Transcriptional and Chromatin Accessibility of Tumor Cells Underlines Extensive Cis-Regulatory Interaction during Multiple Myeloma Progression (2024)
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Multi-Omics Reveal Immune Microenvironment Alterations in Multiple Myeloma and Its Precursor Stages (2024)
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Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages (2024)
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DNA structural features and variability of complete MHC locus sequences (2024)
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A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation (2024)
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Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone (2024)
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Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth (2024)
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A framework for defining mesenchymal cell types associated with murine periosteal and endosteal bone (2023)
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High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma (2023)
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A gene signature can predict risk of MGUS progressing to multiple myeloma (2023)
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A Gene Signature Can Predict Risk of MGUS Progressing to Multiple Myeloma (2023)
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A 12 Gene Signature Accurately Predicts Multiple Myeloma Progression from Monoclonal Gammopathy of Undetermined Significance (2022)
Grants & Funding
- Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator
- Center for Musculoskeletal Disease Research (CMDR) NIH/Nat. Inst. of General Medical Sciences Principal Investigator
- Project 1 – Prevention of MGUS progression to MM by modulating the bone marrow microenvironment NIH/Nat. Cancer Institute - Pass Through: Baylor College of Medicine Principal Investigator
Collaboration Network
Top Collaborators
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Showing 5 of 13 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Showing 5 of 12 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation
Showing 5 of 12 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
- A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation
- The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting CST6 Against Multiple Myeloma and Suppresses Osteolytic Lesions
Showing 5 of 12 shared publications
- CReSIL: accurate identification of extrachromosomal circular DNA from long-read sequences
- Native RNA or cDNA Sequencing for Transcriptomic Analysis: A Case Study on Saccharomyces cerevisiae
- Refining the identity of mesenchymal cell types associated with murine periosteal and endosteal bone
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- Two SARS-CoV-2 Genome Sequences of Isolates from Rural U.S. Patients Harboring the D614G Mutation, Obtained Using Nanopore Sequencing
Showing 5 of 11 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Showing 5 of 11 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Showing 5 of 11 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Showing 5 of 11 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Showing 5 of 11 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
Showing 5 of 11 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
- A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation
- The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting CST6 Against Multiple Myeloma and Suppresses Osteolytic Lesions
Showing 5 of 11 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation
Showing 5 of 10 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- A Risk Stratification System in Myeloma Patients with Autologous Stem Cell Transplantation
Showing 5 of 10 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- Multi-omics reveal immune microenvironment alterations in multiple myeloma and its precursor stages
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- Global Proteomics Identifies CDK11A/B As Integral to Myeloma Proliferation and High-Risk Disease
- Multi-Omics Reveal Immune Microenvironment Alterations in Multiple Myeloma and Its Precursor Stages
Showing 5 of 9 shared publications
- Bispecific BCMA/CD24 CAR-T cells control multiple myeloma growth
- High NEK2 expression in myeloid progenitors suppresses T cell immunity in multiple myeloma
- A gene signature can predict risk of MGUS progressing to multiple myeloma
- BCMA- and CST6-specific CAR T cells lyse multiple myeloma cells and suppress murine osteolytic lesions
- The BCMA-Targeted Fourth-Generation CAR-T Cells Secreting CST6 Against Multiple Myeloma and Suppresses Osteolytic Lesions
Showing 5 of 7 shared publications
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