Sayem Miah
Assistant Professor
faculty
Biochemistry & Molecular Biology, College of Medicine
Research Areas
Links
Biography and Research Information
OverviewAI-generated summary
Sayem Miah's research focuses on understanding the molecular mechanisms underlying cancer, particularly breast cancer. His work investigates oncogenic signaling pathways and their role in regulating chromatin structure during tumorigenesis. Miah has explored how perturbations in protein interactions, such as those involving BRMS1, can influence metastatic processes. He has also examined the potential of targeting specific signaling pathways like TGF-β and investigated novel small molecule inhibitors for kinases like BRK/PTK6. His research integrates multi-omics data to identify regulatory features associated with triple-negative breast cancer and explores the function of proteins like FAM60A in RNA splicing, which can be dysregulated in cancer. Miah's publications also touch upon the mechanisms of drug-induced apoptosis in cancer cells.
Metrics
- h-index: 15
- Publications: 34
- Citations: 505
Selected Publications
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Discovery of Novel 1h-Pyrazolo[3,4-D]Pyrimidine Derivatives as Brk/Ptk6 Inhibitors (2025)
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Beyond the Sin3/HDAC Complex: FAM60A emerges as a regulator of RNA Splicing (2024)
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443 Team Science (2023)
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Targeting TGF-β: Triumphs and Challenges (2022)
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Perturbation of BRMS1 interactome reveals pathways that impact metastasis (2021)
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Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer (2021)
Grants & Funding
- Center for Molecular Interactions in Cancer (CMIC) NIH Co-Investigator
- TRI KL2 Scholars award - Miah UAMS Internal Research Awards Principal Investigator
- TRI KL2 Scholars award - Ashby UAMS College of Medicine Principal Investigator
- AWD-037194: 4721 - Non-Receptor Protein Tyrosine Kinases (nRTKs), GR037194 ABI Non-Receptor Protein Tyrosine Kinases (nRTKs) UAMS ACHRI Flow Through Principal Investigator
Collaboration Network
Top Collaborators
- Targeting TGF-β: Triumphs and Challenges
- 443 Team Science
- Discovery of Novel 1h-Pyrazolo[3,4-D]Pyrimidine Derivatives as Brk/Ptk6 Inhibitors
- Discovery of novel 1H-pyrazolo[3,4-d]pyrimidine derivatives as BRK/PTK6 inhibitors
- Targeting TGF-β: Triumphs and Challenges
- 443 Team Science
- Discovery of Novel 1h-Pyrazolo[3,4-D]Pyrimidine Derivatives as Brk/Ptk6 Inhibitors
- Discovery of novel 1H-pyrazolo[3,4-d]pyrimidine derivatives as BRK/PTK6 inhibitors
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Beyond the Sin3/HDAC Complex: FAM60A emerges as a regulator of RNA Splicing
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Beyond the Sin3/HDAC Complex: FAM60A emerges as a regulator of RNA Splicing
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Perturbation of BRMS1 interactome reveals pathways that impact metastasis
- Perturbation of BRMS1 interactome reveals pathways that impact cell migration
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
- Beyond the Sin3/HDAC Complex: FAM60A emerges as a regulator of RNA Splicing
- Multi-omics data integration reveals correlated regulatory features of triple negative breast cancer
- Beyond the Sin3/HDAC Complex: FAM60A emerges as a regulator of RNA Splicing
- Oncogenic signaling-mediated regulation of chromatin during tumorigenesis
- 443 Team Science
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