Philip R. Mayeux
Professor Emeritus
Also affiliated: Tulane University (1985–1989); Medical University of South Carolina (1988–1991); University of Pittsburgh (2016); Baylor College of Medicine (2016); Tulane Medical Center (1985); Nierstichting (2016); AM–Pharma (Netherlands) (2016); Texas Children's Hospital (2016); Baxter (United States) (2016)
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Philip R. Mayeux's research interests include behavioral and psychological studies, with a focus on health sciences research and education. His work has explored various aspects of health disparities and outcomes, as well as behavioral health and interventions. Mayeux has also been involved in studies related to child and adolescent health, investigating factors that influence well-being and development within this population.
Metrics
- h-index: 38
- Publications: 95
- Citations: 6,243
Positions
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Professor Emeritus publications 1991–2020University of Arkansas for Medical Sciences Institution web page
Selected Publications
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Microvascular Dysfunction in the Critically Ill (2020)
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Retraction Note: Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability (2019)
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Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis. (2018)
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Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome (2017)
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Development of Renal Dysfunction in an Infant Model of Polymicrobial Sepsis (2016)
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Preclinical Evaluation of the Phosphodiesterase‐4 Inhibitor, Rolipram, in an Infant Model of Sepsis‐Induced Cardiorenal Syndrome (2016)
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Delayed Mitogen-Activated Protein Kinase/Extracellular Signal–Regulated Kinase Inhibition by Trametinib Attenuates Systemic Inflammatory Responses and Multiple Organ Injury in Murine Sepsis* (2016)
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Could Biomarkers Direct Therapy for the Septic Patient? (2016)
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RETRACTED ARTICLE: Sepsis-induced elevation in plasma serotonin facilitates endothelial hyperpermeability (2016)
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Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria-targeted antioxidant mitigates injury (2014)
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Targeting mitochondrial oxidants may facilitate recovery of renal function during infant sepsis (2014)
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Pharmacologic Targeting of Sphingosine-1-Phosphate Receptor 1 Improves the Renal Microcirculation during Sepsis in the Mouse (2014)
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Rolipram Improves Renal Perfusion and Function during Sepsis in the Mouse (2013)
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Preclinical evaluation of the mitochondria‐targeted antioxidant mitoquinone to treat sepsis‐induced acute kidney injury (2013)
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Sirtuin 1 enzyme activity and autophagy proteins are increased in the kidney during murine sepsis (2012)
Collaboration Network
Top Collaborators
- Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury
- Development of Oxidative Stress in the Peritubular Capillary Microenvironment Mediates Sepsis-Induced Renal Microcirculatory Failure and Acute Kidney Injury
- Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice
- Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite
- Rolipram Improves Renal Perfusion and Function during Sepsis in the Mouse
Showing 5 of 9 shared publications
- Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria-targeted antioxidant mitigates injury
- Pharmacological targets in the renal peritubular microenvironment: Implications for therapy for sepsis-induced acute kidney injury
- Role of Mitochondrial Oxidants in an In Vitro Model of Sepsis-Induced Renal Injury
- Targeting mitochondrial oxidants may facilitate recovery of renal function during infant sepsis
- Female mice exhibit less renal mitochondrial injury but greater mortality using a comorbid model of experimental sepsis.
Showing 5 of 8 shared publications
- Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury
- Development of Oxidative Stress in the Peritubular Capillary Microenvironment Mediates Sepsis-Induced Renal Microcirculatory Failure and Acute Kidney Injury
- Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice
- Evidence for the Role of Reactive Nitrogen Species in Polymicrobial Sepsis-Induced Renal Peritubular Capillary Dysfunction and Tubular Injury
- Actinonin, a Meprin a Inhibitor, Protects the Renal Microcirculation During Sepsis
Showing 5 of 8 shared publications
- Development of Oxidative Stress in the Peritubular Capillary Microenvironment Mediates Sepsis-Induced Renal Microcirculatory Failure and Acute Kidney Injury
- Role of Mitochondrial Oxidants in an In Vitro Model of Sepsis-Induced Renal Injury
- In Vitro Model of Sepsis-Induced Renal Epithelial Reactive Nitrogen Species Generation
- Reactive nitrogen species generation in a new in‐vitro model of sepsis‐induced renal epithelial injury
- A new in vitro model of sepsis‐induced renal epithelial cell injury
Showing 5 of 7 shared publications
- Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria-targeted antioxidant mitigates injury
- Pharmacologic Targeting of Sphingosine-1-Phosphate Receptor 1 Improves the Renal Microcirculation during Sepsis in the Mouse
- Rolipram Improves Renal Perfusion and Function during Sepsis in the Mouse
- Preclinical evaluation of the mitochondria‐targeted antioxidant mitoquinone to treat sepsis‐induced acute kidney injury
- Renal Mitochondrial Dysfunction: Unraveling the Mystery of Sepsis Induced Renal Injury
Showing 5 of 6 shared publications
- Molecular Cloning and Functional Characterization of a Vasotocin Receptor Subtype That Is Expressed in the Shell Gland and Brain of the Domestic Chicken1
- Heterooligomerization between Vasotocin and Corticotropin-Releasing Hormone (CRH) Receptors Augments CRH-Stimulated 3′,5′-Cyclic Adenosine Monophosphate Production
- Molecular cloning and functional characterization of a vasotocin receptor subtype expressed in the pituitary gland of the domestic chicken (Gallus domesticus): avian homolog of the mammalian V1b-vasopressin receptor
- Transmembrane domain IV of the Gallus gallus VT[sub 2] vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor
- Transmembrane Domain IV of the Gallus gallus VT2 Vasotocin Receptor is Essential for Forming a Heterodimer with the Corticotrophin Releasing Hormone Receptor
- Nitrotyrosine−Protein Adducts in Hepatic Centrilobular Areas following Toxic Doses of Acetaminophen in Mice
- Effect of Inhibitors of Nitric Oxide Synthase on Acetaminophen-Induced Hepatotoxicity in Mice
- Resveratrol, a dietary polyphenolic phytoalexin, is a functional scavenger of peroxynitrite
- Acetaminophen-Induced Hepatotoxicity in Mice Lacking Inducible Nitric Oxide Synthase Activity
- The dietary antioxidant resveratrol is a functional scavenger of peroxynitrite in vitro
- Meprin A and meprin α generate biologically functional IL-1β from pro-IL-1β
- Intracellular calcium mediates the cytotoxicity of lipid A in LLC-PK1 cells.
- Receptor-mediated increase in cytosolic calcium in LLC-PK1 cells by platelet activating factor and thromboxane A2
- Lack of a role for inducible nitric oxide synthase in an experimental model of nephrotic syndrome
- Glomerular thromboxane A2/prostaglandin H2 receptors: characterization and effect of adriamycin-induced nephrotic syndrome
- Pharmacologic Targeting of Sphingosine-1-Phosphate Receptor 1 Improves the Renal Microcirculation during Sepsis in the Mouse
- Targeting mitochondrial oxidants may facilitate recovery of renal function during infant sepsis
- Rolipram Improves Outcome in a Rat Model of Infant Sepsis-Induced Cardiorenal Syndrome
- Preclinical Evaluation of the Phosphodiesterase‐4 Inhibitor, Rolipram, in an Infant Model of Sepsis‐Induced Cardiorenal Syndrome
- Development of Renal Dysfunction in an Infant Model of Polymicrobial Sepsis
- Peritubular capillary dysfunction and renal tubular epithelial cell stress following lipopolysaccharide administration in mice
- Evidence for the Role of Reactive Nitrogen Species in Polymicrobial Sepsis-Induced Renal Peritubular Capillary Dysfunction and Tubular Injury
- Renal peritubular capillary dysfunction and tubular injury following polymicrobial sepsis in mice
- Renal tubule reactive nitrogen species generation and peritubular capillary dysfunction in experimental sepsis in mice
- Nitric Oxide Generation Mediates Lipid A-Induced Oxidant Injury in Renal Proximal Tubules
- Nitric oxide generation by renal proximal tubules: role of nitric oxide in the cytotoxicity of lipid A.
- Superoxide Generation by Renal Proximal Tubule Nitric Oxide Synthase
- Effects of lipid A on calcium homeostasis in renal proximal tubules.
- Heterooligomerization between Vasotocin and Corticotropin-Releasing Hormone (CRH) Receptors Augments CRH-Stimulated 3′,5′-Cyclic Adenosine Monophosphate Production
- Transmembrane domain IV of the Gallus gallus VT[sub 2] vasotocin receptor is essential for forming a heterodimer with the corticotrophin releasing hormone receptor
- Transmembrane Domain IV of the Gallus gallus VT2 Vasotocin Receptor is Essential for Forming a Heterodimer with the Corticotrophin Releasing Hormone Receptor
- Development of Oxidative Stress in the Peritubular Capillary Microenvironment Mediates Sepsis-Induced Renal Microcirculatory Failure and Acute Kidney Injury
- Actinonin, a Meprin a Inhibitor, Protects the Renal Microcirculation During Sepsis
- Sphingosine‐1‐phosphate receptor 1 agonist SEW2871 decreases sepsis‐induced renal microvascular permeability but not peritubular capillary hypoperfusion
- Resveratrol improves renal microcirculation, protects the tubular epithelium, and prolongs survival in a mouse model of sepsis-induced acute kidney injury
- Development of Oxidative Stress in the Peritubular Capillary Microenvironment Mediates Sepsis-Induced Renal Microcirculatory Failure and Acute Kidney Injury
- Renal microcirculatory perfusion in a pediatric model of sepsis‐induced acute kidney injury in the rat
- Inactivation of renal mitochondrial respiratory complexes and manganese superoxide dismutase during sepsis: mitochondria-targeted antioxidant mitigates injury
- Renal Mitochondrial Dysfunction: Unraveling the Mystery of Sepsis Induced Renal Injury
- Sepsis Leads to Inhibition of Renal Manganese Superoxide Dismutase Activity and Mitochondrial Respiration in the Kidney
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