Match tier
Likely match
Presence
Current · Arkansas
Last published
2026
Sources
OpenAlex · ORCID
Refreshed
2026-10-06
R
Rebecca A. Wynne
This is a likely match — the affiliation was inferred from OpenAlex, ORCID, and web sources but has not been fully confirmed. Treat with appropriate caution.
Role not yet determined Is this you? Add your title
Also affiliated: Arkansas Children's Hospital (2013–2016); United States Food and Drug Administration (2003–2026); Arkansas Children's Nutrition Center (2010–2014); Arkansas Children's Research Institute (2013–2018); California State University, Long Beach (2012)
19 h-index
31 pubs
1,511 cited
Research Areas
Biomedical Subjects
Links
Biography and Research Information
OverviewAI-generated summary
Rebecca Wynne's research focuses on assessing the genotoxicity and pulmonary toxicity of various chemical agents using human in vitro models. Her work has investigated the potential damage caused by glutaraldehyde and ortho-phthalaldehyde aerosols in human airway tissue models, employing methods like the CometChip assay and Duplex Sequencing to detect DNA damage and mutations. Wynne has also examined the effects of repeat chemical treatments on somatic cell mutations in these airway cultures. Additionally, her research has explored the role of alcohol consumption in promoting diethylnitrosamine-induced hepatocarcinogenesis in male mice, specifically through the activation of the Wnt/β-catenin signaling pathway.
Wynne collaborates with researchers from the National Center for Toxicological Research, including Kelly E. Mercer, Xuefei Cao, and Robert H. Heflich, and also with Thomas M. Badger from the University of Arkansas for Medical Sciences. She has authored 33 publications and has an h-index of 19 with 1,466 citations.
Metrics
- h-index: 19
- Publications: 31
- Citations: 1,511
Selected Publications
-
Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays (2026)
-
Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations (2024)
-
Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model (2022)
-
Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing (2021)
-
Toxicity of Ortho-phthalaldehyde Aerosols in a Human In Vitro Airway Tissue Model (2021)
-
Inheritance of HLA-Cw7 Associated With Autism Spectrum Disorder (ASD) (2019)
-
Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism (2018)
-
Bioenergetic variation is related to autism symptomatology (2017)
-
Oxidative Stress Challenge Uncovers Trichloroacetaldehyde Hydrate-Induced Mitoplasticity in Autistic and Control Lymphoblastoid Cell Lines (2017)
-
Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder (2017)
-
Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study (2016)
-
Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial (2016)
-
Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines (2016)
-
Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups (2016)
-
Increased Susceptibility to Ethylmercury-Induced Mitochondrial Dysfunction in a Subset of Autism Lymphoblastoid Cell Lines (2015)
Collaboration Network
Top Collaborators
Richard E. Frye
Arkansas Children's Hospital (US)
12 shared publications
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study
- Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines
Showing 5 of 12 shared publications
Shannon Rose
Arkansas Children's Hospital
12 shared publications
In database
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study
- Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines
Showing 5 of 12 shared publications
Marie Tippett
Arkansas Children's Hospital
9 shared publications
In database
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
Showing 5 of 9 shared publications
John M. Slattery
Arkansas Children's Hospital (US)
7 shared publications
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
- Bioenergetic variation is related to autism symptomatology
Showing 5 of 7 shared publications
Stepan Melnyk
Arkansas Children's Hospital
7 shared publications
In database
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study
- Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
Showing 5 of 7 shared publications
Leanna Delhey
Arkansas Children's Hospital
7 shared publications
In database
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
Showing 5 of 7 shared publications
Sirish C. Bennuri
Arkansas Children's Hospital (US)
7 shared publications
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
Showing 5 of 7 shared publications
Stephen G. Kahler
Arkansas Children's Hospital (US)
6 shared publications
- Butyrate enhances mitochondrial function during oxidative stress in cell lines from boys with autism
- Modulation of mitochondrial function by the microbiome metabolite propionic acid in autism and control cell lines
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
- Bioenergetic variation is related to autism symptomatology
Showing 5 of 6 shared publications
S. Jill James
Arkansas Children's Hospital
5 shared publications
In database
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Mitochondrial and redox abnormalities in autism lymphoblastoid cells: a sibling control study
- Oxidative stress induces mitochondrial dysfunction in a subset of autistic lymphoblastoid cell lines
- Increased Susceptibility to Ethylmercury-Induced Mitochondrial Dysfunction in a Subset of Autism Lymphoblastoid Cell Lines
- Mitochondrial dysfunction in immune cells derived from children with autism spectrum disorder (ASD): A unique metabolic endophenotype of children with ASD
Levan Muskhelishvili
National Center for Toxicological Research (US)
4 shared publications
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Kelly J. Davis
National Center for Toxicological Research
4 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Xuefei Cao
National Center for Toxicological Research
4 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Edward V. Quadros
State University of New York (US)
3 shared publications
- Folinic acid improves verbal communication in children with autism and language impairment: a randomized double-blind placebo-controlled trial
- Blocking and Binding Folate Receptor Alpha Autoantibodies Identify Novel Autism Spectrum Disorder Subgroups
- Thyroid dysfunction in children with autism spectrum disorder is associated with folate receptor α autoimmune disorder
Yiying Wang
National Center for Toxicological Research (US)
3 shared publications
- Subacute Pulmonary Toxicity of Glutaraldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Toxicity of Ortho-phthalaldehyde Aerosols in a Human In Vitro Airway Tissue Model
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
Robert H. Heflich
National Center for Toxicological Research
3 shared publications
In database
- Genetic toxicity testing using human in vitro organotypic airway cultures: Assessing DNA damage with the CometChip and mutagenesis by Duplex Sequencing
- Repeat treatment of organotypic airway cultures with ethyl methanesulfonate causes accumulation of somatic cell mutations without expansion of bronchial-carcinoma-specific cancer driver mutations
- Comparative genotoxicity assessment of ortho-phthalaldehyde using human in vitro organotypic airway epithelial cultures and standard in vitro genotoxicity assays
Similar Researchers
Based on overlapping research topics
Nyosha Moore
National Center for Toxicological Research
Carcinogens and Genotoxicity Assessment
Pharmacological Effects and Toxicity Studies
Disease Models, Animal
Audrey M Sims
National Center for Toxicological Research
Carcinogens and Genotoxicity Assessment
Pharmacological Effects and Toxicity Studies
Disease Models, Animal
Michelle E. Bishop
National Center for Toxicological Research
Carcinogens and Genotoxicity Assessment
Pharmacological Effects and Toxicity Studies
Disease Models, Animal
Page B. McKinzie
National Center for Toxicological Research
Carcinogens and Genotoxicity Assessment
Pharmacological Effects and Toxicity Studies
Disease Models, Animal
Ji‐Eun Seo
National Center for Toxicological Research
Carcinogens and Genotoxicity Assessment
Pharmacological Effects and Toxicity Studies
Disease Models, Animal
Xuefei Cao
National Center for Toxicological Research
Carcinogens and Genotoxicity Assessment
Pharmacological Effects and Toxicity Studies
Disease Models, Animal